Abstract In today's digital age, misinformation propagates rapidly through digital channels, blurring the lines between truth and fiction, and challenging the foundations of trust in information sources. Although affecting all spheres of life, misinformation poses a significant threat to workers highlighting a critical intersection between ...
Ashwani Malhotra+4 more
wiley +1 more source
Gametocytes infectiousness to mosquitoes: variable selection using random forests, and zero inflated models [PDF]
Malaria control strategies aiming at reducing disease transmission intensity may impact both oocyst intensity and infection prevalence in the mosquito vector. Thus far, mathematical models failed to identify a clear relationship between Plasmodium falciparum gametocytes and their infectiousness to mosquitoes.
arxiv
ABSTRACT Macrocyclic calix[n]arenes have many applications, with diverse structures that can easily be functionalized either on upper or lower rims, mostly to impart solubility and improve biological activities. In this study, triazole‐based p‐tert‐butylcalix[4]arene conjugates (AT10a and AT10b) and their p‐tert‐butylphenol analogs (AT10b and AT11b ...
Alfred Ngenge Tamfu+2 more
wiley +1 more source
Global estimates and projections of mortality by cause, 1970-2015 [PDF]
The authors report estimates and projections of deaths by cause for major world regions, based on data from country reports to the World Health Organization and regression models.
Bulatao, Rodolfo A.+1 more
core
Laboratory surveillance of communicable diseases : enteric pathogens [PDF]
Laboratories represent a crucial link in the surveillance chain. Since only a small proportion of cases of enteric infections are asked to submit a stool sample, one needs to assess the practices for testing for enteric pathogens and their notification ...
Gauci, Charmaine+3 more
core
Multi-parallel qPCR provides increased sensitivity and diagnostic breadth for gastrointestinal parasites of humans: field-based inferences on the impact of mass deworming [PDF]
BACKGROUND: Although chronic morbidity in humans from soil transmitted helminth (STH) infections can be reduced by anthelmintic treatment, inconsistent diagnostic tools make it difficult to reliably measure the impact of deworming programs and often miss
A Ebrahim+75 more
core +3 more sources
Influenza-associated mortality for different causes of death during the 2010-2011 through the 2014-2015 influenza seasons in Russia [PDF]
Background: There is limited information on the volume of influenza-associated mortality in Russia. Methods: Using previously developed methodology (Goldstein et al., Epidemiology 2012), we regressed the monthly rates of mortality for respiratory causes, circulatory causes, and for certain infectious and parasitic diseases (available from the Russian
arxiv
Abstract Aim To evaluate the safety, tolerability and pharmacokinetics in healthy participants of orally administered MMV367 (GSK3772701), a novel antimalarial interfering with Plasmodium falciparum acyl coenzyme A synthetase 10/11 function. Methods This first‐in‐human study enrolled 47 healthy male and female participants.
Andrea Kuemmerle+13 more
wiley +1 more source
Implications From the Analogous Relationship Between Evolutionary and Learning Processes
Organismal evolution resembles learning processes in many aspects, but the analogy has not been widely recognized. We discuss new opportunities inspired by this analogy to enhance predictive capabilities and theoretical developments in both research fields, especially using white‐box modeling for expanding predictive theory in evolutionary biology ...
Jason Cheok Kuan Leong+3 more
wiley +1 more source
Towards life cycle identification of malaria parasites using machine learning and Riemannian geometry [PDF]
Malaria is a serious infectious disease that is responsible for over half million deaths yearly worldwide. The major cause of these mortalities is late or inaccurate diagnosis. Manual microscopy is currently considered as the dominant diagnostic method for malaria. However, it is time consuming and prone to human errors.
arxiv