Results 111 to 120 of about 310,033 (365)

Multi-parallel qPCR provides increased sensitivity and diagnostic breadth for gastrointestinal parasites of humans: field-based inferences on the impact of mass deworming [PDF]

, 2016
BACKGROUND: Although chronic morbidity in humans from soil transmitted helminth (STH) infections can be reduced by anthelmintic treatment, inconsistent diagnostic tools make it difficult to reliably measure the impact of deworming programs and often miss
A Ebrahim, A Jeandron, AC Clements, AJ Branscum, Alice V. Easton, B Levecke, B Nikolay, BA Boatin, Cassian Mwatele, Charles S. Mwandawiro, CR Stensvold, CV Holland, D Croce, D Engels, D Glinz, D Mupfasoni, DA Bundy, DA Bundy, DB Elkins, DJ Lunn, DM Deer, Elise M. O’Connell, FA Jonker, FL Santos, HL Guyatt, J Martin, JE Forrester, Jimmy H. Kihara, JJ Verweij, JJ Verweij, Joanne P. Webster, JP Webster, JS McCarthy, KE Hoagland, LM Assefa, LS Diamond, M Albonico, M Basuni, M Booth, M Taniuchi, Maurice R. Odiere, MO Harhay, N Katz, N Katz, NA Croll, P Hotez, PH Lamberton, R Anderson, R Bergquist, R Mejia, RD Pearson, Rita G. Oliveira, RJ Hove ten, RK Prichard, RL Pullan, RL Pullan, RM Anderson, RM Anderson, RO Cimino, Roy M. Anderson, S Brooker, S Brooker, S Knopp, S Knopp, S Knopp, S Lustigman, S Williams-Blangero, Sammy M. Njenga, SC Knowles, Simon J. Brooker, SJ Krauth, Stella Kepha, Thomas B. Nutman, TW Jia, WHO, XP Ye   +75 more
core   +3 more sources

Principles for Rigorous Design and Application of Synthetic Microbial Communities

Advanced Science, EarlyView.
SynComs are artificially designed to enable inter‐species metabolic interactions, metabolic division of labor, and ecological interactions that can elicit phenotypes like colonization stability and environmental adaptation. This systematic review explores the processes used to construct SynComs, the assessment of the mechanisms of metabolic interaction
Yuxiao Zhang, Minyu Jing, Lihui Lyu, Li Nie, Xihui Xu, Ru Sun, Xiyuan Xu, Siyu Chen, Shuobing He, Yumeng Zhang, Ping Huang, Weijie Luo, Jiaojiao Liang, Guifeng Gao, Kunkun Fan, Teng Yang, Liyan Zhang, Xiao Fu, Sarah M. Allard, Jack A. Gilbert, Jiabao Zhang, Haiyan Chu   +21 more
wiley   +1 more source

T CELL EFFECTOR AND REGULATORY SUBSETS, DIFFERENTIATING BETWEEN ACTIVE AND LATENT MTB INFECTION

Problems of Infectious and Parasitic Diseases, 2019
Last generation IFN gamma – based assays (IGRAs) evaluate bulk CD4 and CD8 T cell responses, and do not discriminate between latent and active Micobacterium tuberculosis (MTB) infection.
Yana Todorova , Radoslava Emilova, Vladimir Milanov , Lilia Eneva, Elizabeta Bachiyska, Yuliana Atanasova, Ana Baykova, Maria Nikolova   +7 more
doaj   +1 more source

Stromal Cell‐Mast Cell Communication Orchestrates Anti‐Viral Immunity in the Meninges

Advanced Science, EarlyView.
This study delineates the spatial distribution and postnatal maturation of meningeal mast cells and uncovers their essential role in antiviral immunity. Using genetic models, mast cells are shown to promote CD8⁺ T cell infiltration and viral clearance via IL‐33 receptor signaling and synergistic activation by IL‐33 and ATP from infected stromal cells ...
Qingqing Li, Weijia Chen, Mengxue Sun, Xinbo Ni, Qishan Ran, Xiaoyu Hu, Fang Cao, Wenwen Zeng   +7 more
wiley   +1 more source

Global trends in infectious diseases at the wildlife–livestock interface [PDF]

, 2015
The role and significance of wildlife–livestock interfaces in disease ecology has largely been neglected, despite recent interest in animals as origins of emerging diseases in humans. Scoping review methods were applied to objectively assess the relative
Anke K. Wiethoelter, Bengis, Bengis, Chardonnet, Daniel Beltrán-Alcrudo, Dehove, Kock, Muggeo, Richard Kock, Siobhan M. Mor, Song, Williams   +11 more
core   +2 more sources

Aptamer Engineering: Strategies for Discovering Functional Nucleic Acids for Next‐Generation Diagnostics and Biosensing

Advanced Science, EarlyView.
The advent of aptamers has highlighted their potential as alternatives to antibodies, overcoming limitations of structural instability and production cost. However, conventional approaches such as SELEX remain slow and labor‐intensive. This review examines recent advances in aptamer engineering, emphasizing in vitro and AI‐driven in silico strategies ...
John V. L. Nguyen, Ahlem Meziadi, Cyrill Brunner, Maureen McKeague, Lidija Malic, Maryam Tabrizian   +5 more
wiley   +1 more source

Clinical presentations of viral and parasitic diseases in HIV infection [PDF]

, 2012
Представлений аналіз залежності клінічних проявів інфекцій вірусної і паразитарної етіології на тлі ВІЛ-інфекції від рівня CD4-лімфоцитів. При цитуванні документа, використовуйте посилання http://essuir.sumdu.edu.ua/handle/123456789/26618Представлен ...
Magufwa, Alex, Piddubna, Anna Ivanivna, Магуфва, Алекс, Магуфва, Алекс, Поддубная, Анна Ивановна, Піддубна, Анна Іванівна   +5 more
core  

Nanozymes Integrated Biochips Toward Smart Detection System

Advanced Science, EarlyView.
This review systematically outlines the integration of nanozymes, biochips, and artificial intelligence (AI) for intelligent biosensing. It details how their convergence enhances signal amplification, enables portable detection, and improves data interpretation.
Dongyu Chen, Wang Zheng, Zhihui Zhang, Shenping Yu, Xinxin Hang, Han Wu, Xiao‐Wei Xiang, Wei Mu, Yanli Jiao, Zaizai Dong, Lingqian Chang   +10 more
wiley   +1 more source

Global estimates and projections of mortality by cause, 1970-2015 [PDF]

The authors report estimates and projections of deaths by cause for major world regions, based on data from country reports to the World Health Organization and regression models.
Bulatao, Rodolfo A., Stephens, Patience W.   +1 more
core  

Climate‐Smart Dairy Practices: The Role of Practice Clusters in Enhancing the Performance of Dairy Farms in Kenya

Agribusiness, EarlyView.
ABSTRACT Climate variability is affecting the productivity, profitability, and resilience of smallholder dairy producers in developing countries. The adoption of climate‐smart (CS) dairy practices has been promoted to mitigate these negative effects. However, while interest in dairy CS practices is growing, empirical evidence on their adoption patterns
Mercy Mburu, Amin Mugera, John Mburu, Rose Nyikal, Oghaiki Asaah Ndambi   +4 more
wiley   +1 more source