Results 111 to 120 of about 297,316 (346)

The rule of five should not impede anti-parasitic drug development. [PDF]

open access: yes, 2017
The "rule of 5" has become a mainstay of decision-making in the pharmaceutical industry as well as in nonindustrial (academic and institutional) drug development.
Lipinski, Christopher A   +1 more
core   +1 more source

Genome‐Wide Protein Interaction Analysis in Parasitic Gyrodactylus Flatworms–Fish Hosts System and Drug Target Identification

open access: yesAdvanced Science, EarlyView.
Genomic data offer a powerful tool for studying the molecular interactions between parasites and their hosts, but they remain scarce for parasitic monogenean flatworms. This study presents the first high‐quality phased genome assembly for monogeneans (Gyrodactylus kobayashii), and uses it to predict key interacting proteins between monogenean parasite ‐
Dong Zhang   +17 more
wiley   +1 more source

Climate‐Smart Dairy Practices: The Role of Practice Clusters in Enhancing the Performance of Dairy Farms in Kenya

open access: yesAgribusiness, EarlyView.
ABSTRACT Climate variability is affecting the productivity, profitability, and resilience of smallholder dairy producers in developing countries. The adoption of climate‐smart (CS) dairy practices has been promoted to mitigate these negative effects. However, while interest in dairy CS practices is growing, empirical evidence on their adoption patterns
Mercy Mburu   +4 more
wiley   +1 more source

Global trends in infectious diseases at the wildlife–livestock interface [PDF]

open access: yes, 2015
The role and significance of wildlife–livestock interfaces in disease ecology has largely been neglected, despite recent interest in animals as origins of emerging diseases in humans. Scoping review methods were applied to objectively assess the relative
Anke K. Wiethoelter   +11 more
core   +2 more sources

Intelligent Theranostic Systems Enabled by Aggregation‐Induced Emission in Precision Medicine

open access: yesAggregate, EarlyView.
Aggregation‐induced emission (AIE) luminogens are driving a new generation of intelligent theranostic systems that integrate high‐fidelity imaging and multifunctional therapy. This review highlights how AIEgens, through restriction of intramolecular motion (RIM), enable deep‐tissue NIR‐II imaging, ultrasensitive biosensing, CRISPR‐assisted gene ...
Qinqin Huang   +7 more
wiley   +1 more source

Challenges and Opportunities in Combining Ultrasound and Inductive Coupling for Energy Supply and Bidirectional Data Exchange in Bioelectronics Medicine Implant Networks

open access: yesAdvanced Intelligent Systems, EarlyView.
In this contribution, it is shown that miniaturized nerve stimulation implants can be used in collaborative networks. Inductive links and ultrasound are combined to supply these implants with energy and data; the advantages and disadvantages of each method, as well as safety risks and possibilities for improvement are discussed and the best ...
Benedikt Szabo   +5 more
wiley   +1 more source

Three New Manzamine Alkaloids from a Common Indonesian Sponge and Their Activity against Infectious and Tropical Parasitic Diseases [PDF]

open access: green, 2004
Karumanchi V. Rao   +5 more
openalex   +1 more source

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