British Journal of Clinical Pharmacology, EarlyView.Abstract Aim To evaluate the safety, tolerability and pharmacokinetics in healthy participants of orally administered MMV367 (GSK3772701), a novel antimalarial interfering with Plasmodium falciparum acyl coenzyme A synthetase 10/11 function. Methods This first‐in‐human study enrolled 47 healthy male and female participants.
Andrea Kuemmerle +13 more
wiley +1 more source
Sex as a risk factor for occurrence and severity of infectious and parasitic diseases in dogs: Protocol for a systematic review. [PDF]
PLoS One, 2022 Byaruhanga C, Knobel D.
europepmc +1 more source
Analysis of a malaria model with mosquito host choice and bed-net control [PDF]
arXiv, 2013 A malaria model is formulated which includes the enhanced attractiveness of infectious humans to mosquitoes, as result of host manipulation by malaria parasite, and the human behavior, represented by insecticide-treated bed nets usage. The occurrence of a backward bifurcation at R_0=1 is shown to be possible, which implies that multiple endemic ...
arxiv
Disease monitoring and biosecurity [PDF]
, 2009 Understanding and detecting diseases of amphibians has become vitally important in conservation and ecological studies in the twenty-fi rst century. Disease is defi ned as the deviance from normal conditions in an organism.
Gray, Matthew J. +2 more
core +1 more source
Hospital admissions due to infectious and parasitic diseases in England and Wales between 1999 and 2019: an ecological study. [PDF]
BMC Infect Dis, 2022 Sweiss K +3 more
europepmc +1 more source
A Fourfold Pathogen Reference Ontology Suite [PDF]
arXivInfectious diseases remain a critical global health challenge, and the integration of standardized ontologies plays a vital role in managing related data. The Infectious Disease Ontology (IDO) and its extensions, such as the Coronavirus Infectious Disease Ontology (CIDO), are essential for organizing and disseminating information related to infectious ...
arxiv
EVALUATION OF POPULATION-LEVEL IMMUNITY TO SARS-COV-2 ACROSS BULGARIA (END OF 2023)
Problems of Infectious and Parasitic DiseasesBackground: The COVID-19 pandemic in Bulgaria was characterized by a high mortality rate and vaccination efforts yielded suboptimal results. Understanding population immunity is important as new SARS-CoV-2 variants continue to emerge.
Kim Ngoc +8 more
doaj +1 more source
Three New Manzamine Alkaloids from a Common Indonesian Sponge and Their Activity against Infectious and Tropical Parasitic Diseases [PDF]
, 2004 Karumanchi V. Rao +5 more
openalex +1 more source
Challenges in Modeling Complexity of Neglected Tropical Diseases: Assessment of Visceral Leishmaniasis Dynamics in Resource Limited Settings [PDF]
arXiv, 2016 Neglected tropical diseases (NTD), particularly vector-borne diseases (VBD), account for a large proportion of the global disease burden, and their control faces several challenges including diminishing human and financial resources for those distressed from such diseases.
arxiv
Analyzing the Changes in Certain Infectious and Parasitic Diseases in Urban Population of India By Using Medical Certification of Cause of Death Data. [PDF]
Indian J Community Med, 2021 Gulati BK, Sharma S, Vardhana Rao MV.
europepmc +1 more source