Results 141 to 150 of about 254,442 (298)

Proteoforms in Disease: Biomedical Applications of Top‐Down Proteomics

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT The proteome is a dynamic landscape of proteoforms arising from genetic mutations, alternative splicing, and post‐translational modifications (PTMs), which collectively drive biological function and disease phenotypes. Mass spectrometry (MS)‐based proteomics has emerged as an essential technique for elucidating this molecular complexity ...
Holden T. Rogers   +5 more
wiley   +1 more source

Repurposing antimicrobial agents for neuroprotection: Mechanisms, clinical potential, and challenges

open access: yesNeuroprotection, EarlyView.
Antimicrobial agents exert neuroprotective effects through modulation of interconnected pathways. Tetracyclines, macrolides, antimalarial agents, sulfones, and antiparasitic agents suppress neuroinflammation, oxidative stress, and apoptosis while preserving mitochondrial function and neurotransmission.
Mohammad Amin Manavi   +5 more
wiley   +1 more source

Applications of nanocarrier‐delivered RNA interference in agricultural biological control (2009–2025)

open access: yesNew Plant Protection, EarlyView.
Despite 17 years of development, the effectiveness of nanocarrier‐delivered RNAi pesticide (NDRP) for agricultural biological control remains limited. The successful development of effective NDRP development requires the coordinated optimization of target gene selection and nanocarrier properties, including RNA dosage, multi‐gene targeting, protection ...
Shi Dong Wang   +4 more
wiley   +1 more source

Toxoplasma gondii Infection After Kidney Transplantation: A Case Report and Literature Review

open access: yesOrgan Medicine, EarlyView.
Toxoplasma gondii infection after kidney transplantation is rare and presents with nonspecific clinical manifestations; however, the associated mortality rate is high. We discuss the relevant literature, clinical manifestations, therapeutic regimens, and prognoses of post‐transplantation toxoplasmosis.
Peng Zhang   +8 more
wiley   +1 more source

Prevention of zoonotic transmission of ascarids and hookworms. of dogs and cats

open access: yes
"Ascarids ( Toxocara canis, T. cati) and hookworms (Ancylostoma spp.) are common intestinal parasites of dogs and cats (referred to here as pets). Not only can ascarids and hookworms cause disease in their respective hosts, they are also well-known ...

core  

From settler gardens to digital naturalists: human aesthetic preferences and land use changes facilitate the biogeographical expansion of a wild plant–virus interaction

open access: yesPLANTS, PEOPLE, PLANET, EarlyView.
Anthropogenic facilitation of wild plants based on aesthetic preferences for particular traits can change the biogeography and ecology of natural communities. We use a mixed‐methods socioecological approach to characterize the ways in which humans interact with a common, widely distributed plant and a generalist viral symbiont that induces an ...
Elizabeth M. Lombardi   +3 more
wiley   +1 more source

Artificial intelligence at the frontlines: Emerging infectious and parasitic diseases in the digital era. [PDF]

open access: yesNew Microbes New Infect
Nasr DS   +6 more
europepmc   +1 more source

Identification of Novel CD52+ Fibroblasts in Nodular Prostatic Hyperplasia

open access: yesThe Prostate, EarlyView.
ABSTRACT Background Benign prostatic hyperplasia (BPH) and lower urinary tract symptoms are strongly associated with chronic prostate inflammation and stromal remodeling, yet the stromal cell programs that emerge during inflammatory, nodular remodeling remain incompletely defined. A Toxoplasma gondii infection model produces persistent inflammation and
Oliver R. Strobel   +5 more
wiley   +1 more source

Stray Dogs as Reservoirs and Sources of Infectious and Parasitic Diseases in the Environment of the City of Uralsk in Western Kazakhstan. [PDF]

open access: yesBiology (Basel)
Nametov A   +9 more
europepmc   +1 more source

Soil‐dependent variation in strigolactone signaling distance revealed by a parasitic seed germination bioassay

open access: yesPest Management Science, EarlyView.
A parasitic seed germination bioassay reveals strong soil‐dependent variation in strigolactone signaling distance, controlled by physical and biological soil properties, which shapes signaling range and parasitic weed infection risk. Abstract BACKGROUND Strigolactones are root‐exuded plant metabolites acting as germination stimulants for several ...
Hammam Ziadne   +2 more
wiley   +1 more source

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