Results 191 to 200 of about 824,937 (282)

Age‐Associated B Cells Contribute to Inflammation Via Antibody‐Independent Mechanisms in Takayasu Arteritis

open access: yesArthritis &Rheumatology, EarlyView.
Objective Although Takayasu arteritis (TAK) is not a prototypical autoantibody‐mediated disease, accumulating evidence suggests that B cells are involved. This study aimed to investigate the pathway of B cell activation and its contributions to TAK pathogenesis. Methods Histologic analysis of paravascular lymph nodes and affected arteries was conducted
Chenglong Fang   +10 more
wiley   +1 more source

Risk of Cancer according to Duration of Targeted Therapy Exposure in Spondyloarthritis: A Nationwide Cohort Study from the French Health Insurance Database

open access: yesArthritis &Rheumatology, Accepted Article.
Objective To assess the association between duration of targeted therapy exposure and cancer risk in patients with spondyloarthritis (SpA), including those with psoriatic arthritis, axial SpA, and other subtypes. Methods This nationwide cohort study used the French health insurance database to identify adults with SpA initiating a targeted therapy ...
Karine Tankovic   +7 more
wiley   +1 more source

Association Between Chikungunya Infection and Rheumatoid Arthritis in Taiwan-A Cross-Sectional Study. [PDF]

open access: yesInt J Rheum Dis
Yen CY   +12 more
europepmc   +1 more source

Complement activation linked to type II interferon signaling in Still disease

open access: yesArthritis &Rheumatology, Accepted Article.
Objective Still disease (SD) is an autoinflammatory syndrome characterized by innate immune dysregulation. While complement can drive inflammation, its involvement in SD remains to be defined. Thus, we aimed to assess complement activation in SD. Methods Complement was assessed using transcriptomic, proteomic, and in vitro approaches. RNA sequencing of
Freya M.C.H. Huijsmans   +115 more
wiley   +1 more source

Plasma proteome reflects tissue damage and clinical manifestations in patients with inflammatory myopathies

open access: yesArthritis &Rheumatology, Accepted Article.
Objective Tissue‐specific biomarkers that are reliable and associated with clinical manifestations of idiopathic inflammatory myopathy (IIM) are lacking. The blood circulation in individuals serves as a central conduit, allowing communication between tissues and facilitating clearance and recycling of tissue‐derived proteins.
Yue‐Bei Luo   +23 more
wiley   +1 more source

Persistent IL‐18 fuels expansion of CD38+HLA‐DR+CD8+ T cells in Still's disease and macrophage activation syndrome

open access: yesArthritis &Rheumatology, Accepted Article.
Objective Still's disease (SD) is an autoinflammatory disorder characterized by remarkably high IL‐18 levels. Increasing evidence suggests that adaptive immunity also contributes to its pathogenesis, particularly in refractory courses. Macrophage activation syndrome (MAS), one of SD's most severe complications, is associated with further IL‐18 ...
Greta Rogani   +17 more
wiley   +1 more source

Superior Capsular Reconstruction Technique for Massive Rotator Cuff Tear With Arthroscopic Transfer and Augmentation of Long Head of Biceps Brachii Tendon—The Biobridge Technique

open access: yesArthroscopy Techniques, EarlyView.
Abstract Massive irreparable rotator cuff tears remain a major surgical challenge, often leading to pain, functional loss, and superior humeral migration. Superior capsular reconstruction has emerged as a technique to restore superior stability.
Vrgoč Goran   +3 more
wiley   +1 more source

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