Results 261 to 270 of about 1,221,083 (383)

Drug Discovery Applications of Nitroso (Hetero)Arene Derivatives

ChemPlusChem, EarlyView.
Nitroso (hetero)aromatic compounds are bioactive molecules with antiviral, anticancer, neuroprotective, and antimicrobial properties. This review highlights their mechanisms of action—oxidative stress, DNA damage, and enzyme inhibition—alongside synthesis, structure–activity relationships, and toxicity challenges, offering insight into their ...
Silvia Roscales, Aurelio G. Csáky
wiley   +1 more source

A Rare Presentation of Invasive Nontypeable <i>Haemophilus influenzae</i> With Systemic Involvement: A Case Report. [PDF]

Case Rep Infect Dis
Nosheen H, Bellamkonda L, Youssef JG, Ghatol A, Ali SN.   +4 more
europepmc   +1 more source

Seronegative Rheumatoid Arthritis in State Phase Manifesting as Rheumatoid Lung Associated with Co-Infection SARS-Cov-2 and Klebsiella Pneumoniae, In a Context of Probable Variable Expression Hypogammaglobulinemia. At the Intersection of Immunology and Infectious Diseases: Case Report and Literature Review

Ibrahima Amadou Dembélé, Stéphane Loïque Djeugoue, Kaly Keïta, Mamadou Cissoko, Adama Sinayoko, P. Ibrahim, S Diallo, Sidi Touré, Dongue Tsanou Léa Danielle, Korotoumou Traoré, Mamadou Bakary Kone, Aly Timbiné, Trésor Fotouo Metoudou, Ange-Larissa T Medjonye, A. Sangaré, L Koné, Soumare Assitan, Achta Ahmat A Hassane, Jules Verlaine N Tchoundjeu, Tientcheu Toko Dorette, Landouré Sekou, Aoua Diarra, Yacouba Koné, O Dembélé, Nouhoum Koné, Moussa Sangaré, Romuald N Nyanké, Mamadou Mallé, Sy Djibril, D Traoré, Issa Konaté, Didier Mukéba Tshialala, Abrar‐Ahmad Zulfiqar, Soukho Assétou Kaya, Hamar Alassane Traoré   +34 more
openalex   +1 more source

Rules of Thumb for Estimating Drug Levels in Breast Milk: How Well Do They Work?

Clinical Pharmacology &Therapeutics, EarlyView.
The American Academy of Pediatrics and the World Health Organization recommend exclusive breastfeeding for the first 6 months of life due to extensive benefits for the maternal–infant dyad. While over 90% of mothers initiate breastfeeding, continuation drops to 35% by 6 months, often due to concerns about medication safety.
Juliya Gasparyan, Philip O. Anderson, Tamorah Lewis, Cindy H. T. Yeung   +3 more
wiley   +1 more source

Extraintestinal Manifestations of <i>Clostridioides difficile</i> Infections: An Overview. [PDF]

Antibiotics (Basel)
Mpakogiannis K, Fousekis FS, Elemes S, Mantellos E, Christaki E, Katsanos KH.   +5 more
europepmc   +1 more source

Epidemiology of Staphylococcus aureus infections in patients admitted to freestanding pediatric hospitals, 2009-2016 [PDF]

, 2018
Banerjee, Ritu, Brogan, Thomas V, Courter, Joshua D, Gerber, Jeffrey S, Hersh, Adam L, Kronman, Matthew P, Lee, Brian R, Newland, Jason G, Parker, Sarah K, Patel, Sameer J, Shah, Samir S, Smith, Michael J, Spaulding, Alicen B, Thurm, Cary   +13 more
core   +1 more source

Nonsteroidal Anti‐Inflammatory Drugs and Risk of Gastrointestinal Bleeding: A Systematic Review and Meta‐Analysis

Clinical Pharmacology &Therapeutics, EarlyView.
Nonsteroidal anti‐inflammatory drugs (NSAIDs) are widely used for pain and inflammation but are associated with gastrointestinal (GI) bleeding. While this risk is well established, most studies evaluate NSAIDs as a homogenous class, limiting clinical decision‐making based on individual agent safety.
Abdelrahman G. Tawfik, Ainhoa Gomez‐Lumbreras, Guilherme Del Fiol, Kensaku Kawamoto, Katy E. Trinkley, Thomas Reese, Aubrey Jones, Daniel C. Malone   +7 more
wiley   +1 more source

Undifferentiated inflammatory arthritis in a tuberculosis-positive patient: a diagnostic and therapeutic challenge - a case report. [PDF]

Ann Med Surg (Lond)
Gupta P, Katwal P, Adhikari P, Katwal S, Thapa R, Regmi N, Kurmi RN, Gurung S.   +7 more
europepmc   +1 more source

Pharmacomicrobiomics

Clinical Pharmacology &Therapeutics, EarlyView.
Oral medications encounter gut commensal microbes that participate directly and indirectly in drug effects through metabolism, interactions with drug metabolites, or production of substrates that compete with drugs for drug‐metabolizing enzymes, consequently influencing drug pharmacokinetics.
Naomi Gronich, Naama Geva‐Zatorsky, Rachel Herren, Libusha Kelly, Ziv Cohen, Haiying Zhou, Yi‐Ching Chen, Khalid Shah, Talin A. Robinson‐Catala, Grecia Frisby, Jason H. Karnes, Lisl Shoda   +11 more
wiley   +1 more source

Epidemiology and outcomes of Candida-associated osteoarticular infections: A multicentre retrospective study from Turkey. [PDF]

Med Mycol
Güler Ö, Üzel M, Tepe D, Aksoy F, Çınar G, Memikoğlu KO, Durdu B, Ünver Ulusoy T, Benli̇ A, Karakaşoğlu Z, Saltoğlu N, Seyman D, Alıravcı ID, Yaqoobi H, Aydın A, Öztürk Çerik H, Özdemir S, Sümer B, Yetişgen A, Batırel A, Özel AS, Şenbayrak S, Tezer Tekçe Y, Karakoç ZÇ.   +23 more
europepmc   +1 more source