npj Vaccines, 2021 Highly pathogenic emm1 Streptococcus pyogenes strains secrete the multidomain Streptococcal inhibitor of complement (SIC) that binds and inactivates components of the innate immune response. We aimed to determine if naturally occurring or vaccine-induced
Lionel K. K. Tan +10 more
doaj +1 more source
The Dynamics of Real-Time Online Information and Disease Progression: Understanding Spatial Heterogeneity in the Relationship [PDF]
, 2019 The re-emergence of infectious diseases such as measles and polio is creating logistics challenges for the state authorities to curb their spread and contain them.
Chen, Kuanchin +2 more
core +1 more source
The role of fibroblast growth factors in cell and cancer metabolism
FEBS Letters, EarlyView.Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley +1 more source
Development of the gut microbiota during early life in premature and term infants
Gut Pathogens, 2023 Background The gastrointestinal (GI) microbiota has been linked to health consequences throughout life, from early life illnesses (e.g. sepsis and necrotising enterocolitis) to lifelong chronic conditions such as obesity and inflammatory bowel disease ...
Kathleen Sim +4 more
doaj +1 more source
Tissue Tropism in Host Transcriptional Response to Members of the Bovine Respiratory Disease Complex. [PDF]
, 2017 Bovine respiratory disease (BRD) is the most common infectious disease of beef and dairy cattle and is characterized by a complex infectious etiology that includes a variety of viral and bacterial pathogens.
Behura, Susanta K +11 more
core +3 more sources
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Wellcome Open Research, 2021 Background: As of August 2021, every region of the world has been affected by the COVID-19 pandemic, with more than 196,000,000 cases worldwide. Methods: We analysed COVID-19 cases among travellers from mainland China to different regions and countries ...
Sangeeta Bhatia +26 more
doaj +1 more source
Semiparametric Relative-risk Regression for Infectious Disease Data
, 2012 This paper introduces semiparametric relative-risk regression models for infectious disease data based on contact intervals, where the contact interval from person i to person j is the time between the onset of infectiousness in i and infectious contact ...
Kenah, Eben
core +1 more source
A Role for the Intestinal Microbiota and Virome in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)? [PDF]
, 2016 Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a heterogeneous disorder of significant societal impact that is proposed to involve both host and environmentally derived aetiologies that may be autoimmune in nature. Immune-related symptoms
Acheson +22 more
core +2 more sources
Diagnostic accuracy of metagenomic next-generation sequencing in diagnosing infectious diseases: a meta-analysis [PDF]
, 2022 Jian Liu +4 more
openalex +1 more source