Results 111 to 120 of about 118,982 (297)

Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy

Advanced Healthcare Materials, EarlyView.
The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq, Punnya Anil Kumar Jeeja, Sudip Kumar Dam, Sabya Sachi Das, Juan L. Vivero‐Escoto   +4 more
wiley   +1 more source

Systematic Comparison of Commercial Uranyl‐Alternative Stains for Negative‐ and Positive‐Staining Transmission Electron Microscopy of Organic Specimens

Advanced Healthcare Materials, EarlyView.
Negative‐ and positive‐staining TEM is essential for rapid nanometer‐resolution characterization of organic specimens ranging from nanoparticles to cells. Uranyl salts are widely used negative‐/positive‐stains but are radioactive and highly toxic to users and the environment.
Vera M. Kissling, Stephanie Eitner, Davide Bottone, Gea Cereghetti, Peter Wick   +4 more
wiley   +1 more source

Evidence-based decision support for pediatric rheumatology reduces diagnostic errors. [PDF]

, 2016
BACKGROUND: The number of trained specialists world-wide is insufficient to serve all children with pediatric rheumatologic disorders, even in the countries with robust medical resources. We evaluated the potential of diagnostic decision support software
Balu Athreya, CD Newgard, CK Correll, CL Deal, David Zurakowski, E Vittinghoff, Elizabeth Y. N. Ang, ES Berner, GD Schiff, Irit Tirosh, JE Allanson, JL McGhee, Jonathan S. Hausmann, JP Marcin, L Feldman, LL Minich, Lynn K. Feldman, M Al Maini, M Henrickson, M Henrickson, Mary Beth F. Son, Michael M. Segal, ML Mayer, MM Segal, MM Segal, O Wegwarth, P Ramnarayan, P Woo, R Tozzoli, Robert P. Sundel, SB Hanauef, WF Bond   +31 more
core   +2 more sources

Advanced Materials for Biological Field‐Effect Transistors (Bio‐FETs) in Precision Healthcare and Biosensing

Advanced Healthcare Materials, EarlyView.
This review explores how advanced materials enhance Bio‐FETs for precision healthcare and biosensing. It covers their working principles, surface functionalization, and ultra‐sensitive detection capabilities. The integration of flexible designs, AI, and IoT for real‐time monitoring is discussed, along with challenges like material reproducibility and ...
Minal Pandey, Manish Bhaiyya, Prakash Rewatkar, Jitendra B. Zalke, Nitin P. Narkhede, Hossam Haick   +5 more
wiley   +1 more source

Enhancing Ultrasound Power Transfer: Efficiency, Acoustics, and Future Directions

Advanced Materials, EarlyView.
Implantable devices significantly enhance healthcare but are limited by battery life. Ultrasound power transfer technology offers a promising solution for sustainable operation. This review addresses gaps in current research, particularly in sound field analysis and energy efficiency optimization.
Yi Zheng, Zhuomin Zhang, Yanhu Zhang, Qiqi Pan, Xiaodong Yan, Xuemu Li, Zhengbao Yang   +6 more
wiley   +1 more source

High‐Resolution Patterned Delivery of Chemical Signals From 3D‐Printed Picoliter Droplet Networks

Advanced Materials, EarlyView.
3D‐printed picoliter droplet networks have been fabricated that control gene expression in bacterial populations by releasing chemical signals with precise spatial definition and high temporal resolution. This system of effector release is widely applicable, offering diverse applications in biology and medicine.
Jorin Riexinger, Thomas Caganek, Xingzao Wang, Yutong Yin, Khoa Chung, Linna Zhou, Hagan Bayley, Ravinash Krishna Kumar   +7 more
wiley   +1 more source

Engineering CAR‐T Therapeutics for Enhanced Solid Tumor Targeting

Advanced Materials, EarlyView.
CART cell therapy has proven effective for blood cancers but struggles with solid tumors due to diverse antigens and complex environments. Recent efforts focus on improving CAR design and validation platforms. Advances in protein engineering, machine learning, and organoid systems aim to enhance CAR‐T therapy against solid tumors.
Danqing Zhu, Won Joon Kim, Hyunjin Lee, Xiaoping Bao, Pilnam Kim   +4 more
wiley   +1 more source

BUSM News and Notes [PDF]

, 1992
Monthly newsletter providing updates of interest to the Boston University School of Medicine ...
Boston University School of Medicine Office of Informational Services
core  

Engineering Magnetotactic Bacteria as Medical Microrobots

Advanced Materials, EarlyView.
Magnetotactic bacteria (MTB) are living microorganisms that produce magnetosomes for navigation using the Earth's geomagnetic field. Their built‐in magnetic components, along with their intrinsic and/or modified biological functions, make them one of the most promising platforms for making future living and programmable microrobots.
Jiaqi Wang, Yi Xing, Michael Ngatio, Paulina Bies, Lu Lucy Xu, Liuxi Xing, Ahmed Zarea, Ashley V. Makela, Christopher H. Contag, Jinxing Li   +9 more
wiley   +1 more source

Challenges in the diagnostics of mantle cell lymphoma in an elderly comorbid patient

Alʹmanah Kliničeskoj Mediciny
We present a case of a rare lymphoproliferative disease diagnosed while differentiating between the causes of exudative-constrictive pericarditis.
Rostislav V. Binyakovskiy, Svetlana V. Borisovskaya, Oleg D. Zaharov, Dmitry G. Kiselev, Sergey V. Lepkov, Alexander V. Melekhov, Igor G. Nikitin, Alexander V. Salikov   +7 more
doaj   +1 more source