Results 241 to 250 of about 142,605 (310)

The growing impact of human papilloma virus (HPV)-associated cancers in men in Costa Rica: epidemiological and economic burden. [PDF]

Front Public Health
Ospina-Henao S, Brenes-Castillo F, Marcano-Lozada M, Betancur-Díaz MA, Medina S, Brenes-Chacon H, Avila-Aguero ML.   +6 more
europepmc   +1 more source

The Immune Microenvironment: New Therapeutic Implications in Organ Fibrosis

Advanced Science, EarlyView.
This review summarizes recent advances in understanding the immune microenvironment's role in fibrosis, focusing on phenotypic/functional alterations of immune cells and their dynamic interactions with other cellular constituents within tissues. The authors further explore therapeutic opportunities and challenges in targeting immune microenvironment ...
Xiangqi Chen, Chuan Wu, Fei Tang, Jingyue Zhou, Li Mo, Yanping Li, Jinhan He   +6 more
wiley   +1 more source

Palau: Non-Communicable Disease Off-Island Treatment Referrals 2020-2022. [PDF]

Int J Environ Res Public Health
Lac Q, Na Y, Tamashiro KK, Withy K, Adelbai-Fraser M, Decherong C, Dever G.   +6 more
europepmc   +1 more source

The Neglected Role of GSDMD C‐Terminal in Counteracting Type I Interferon Signaling

Advanced Science, EarlyView.
The C‐terminal domain of Gasdermin D (GSDMD‐CT) shows functions beyond pyroptosis. GSDMD‐CT negatively regulates IFN‐I signaling during viral infection by triggering autophagic degradation of RIG‐I and TBK1. GSDMD‐CT interacts with retinoic acid‐inducible gene‐I (RIG‐I) and tank‐binding kinase 1 (TBK1), leading to TRIM28‐mediated ubiquitination and ...
Weilv Xu, Suhui He, Wen Shi, Jinxia Xu, Shiyang Liu, Zexu Yu, Danyue Li, Qiao Jin, Yumeng Wang, Zian Zhang, Qian Lv, Yuanxiang Ge, Yunjie Li, Xinyue Li, Nan Chen, Xinyu Fu, Yang Yang, Fushan Shi   +17 more
wiley   +1 more source

Practicing What They Preach: Do Medical Specialty and Subspecialty Conferences Incorporate Physician Wellness Into Their Programs? [PDF]

Cureus
Mahr NM, Thorne DH, Thagard AS.
europepmc   +1 more source

Volumetric Engineered 3D Drug Reservoir Against Diabetic Implant Infection via Cuproptosis‐Like Bacterial Death and Hunger‐Triggered Maintenance of Mitochondrial Integrity

Advanced Science, EarlyView.
This study provides a volumetric engineered 3D drug reservoir to combat diabetic implant infection. Cu‐doped quantum dots induce cuproptosis‐like bacterial death via metabolic collapse, while glucose oxidase triggers hunger‐triggered mitochondrial protection in host cells.
Dize Li, Hongrui Qin, Min Jiang, Hongjiang Wei, Hongyong Zhao, Ping Tang, Guangyu Jian, Henny C van der Mei, Tao Chen   +8 more
wiley   +1 more source

A Phase Separation‐Assisted Pre‐Enrichment Method for Ultrasensitive Respiratory Virus Detection

Advanced Science, EarlyView.
Conventional biomarker enrichment lacks versatility and specificity. Phase separation‐assisted pre‐enrichment (PSAP) is introduced for concurrent antigen (47×) and RNA (44×) enrichment. Tenfold and fivefold lower detection limits for SARS‐CoV‐2 and Influenza, respectively, were achieved.
Yang Cao, Pui Ngan Lau, Alex W.H. Chin, Zhuolin He, Christina C. K. Au Yeung, Kehao Zeng, Haisong Lin, Leo L. M. Poon, Ho Cheung Shum   +8 more
wiley   +1 more source

Anthocyanins Prevent Mastitis Exacerbation by Inhibiting PANoptosis Activation

Advanced Science, EarlyView.
PANoptosis activation is an effective therapeutic target during mastitis progression, and Gasdermin D activation is key factor contributing to blood milk barrier damage during mastitis, while cyanidin 3‐O‐galactoside can inhibit these targets to exert a protective effect. Therefore, the extraction of key active ingredients from plants for the treatment
Rui Feng, Lin Guo, Fan Wang, Qian Zhang, Guoyan Wang, Hefei Huang, Wei Du, Hong An, Yue Yang, Henghui Miao, Peng Zheng, Tingting Chu, Dengke Zhang, Xiaoxue Yan, Xiaoyu Mi, Qian Ma, Weilin Gao, Yushan Li, Song Li, Yong Zhang, Zhenliang Zhu, Yu Wang, Jun Liu, Xu Liu   +23 more
wiley   +1 more source

Engineered Anti‐Senescence Trachea With Post‐Transplanted Regenerative Homeostasis

Advanced Science, EarlyView.
Bioengineered trachea undergoes post‐transplanted senescence, which is found in this study for the first time. Hebe‐ET is designed with dual anti‐senescence strategies: fiber‐film scaffold in cartilage rings for close‐packed cell interaction, and quercetin‐loaded fibrous rings for immune modulation.
Ziyin Pan, Hai Tang, Lanlan Wang, Qingfeng Bai, Yi Chen, Runfeng Cao, Weikang Lin, Lei Wang, Yulong Hu, Guofang Zhao, Minglei Yang, Weiyan Sun, Kun Zhang, Dawei Li, Chang Chen   +14 more
wiley   +1 more source

Pyogenic Granuloma of the Larynx: A Case Report. [PDF]

Int Med Case Rep J
Moallim Hussein AA, Sheikh OA, Mukhtar AA, Abdi IA, Ahmed NM, Mohamed SS, Kahiye MA, Nur MA, Asseyr AF.   +8 more
europepmc   +1 more source