Results 261 to 270 of about 154,289 (311)

HIV Infrastructure Study Birmingham, Alabama [PDF]

, 2015
Berger, Miriam, McAllaster, Carolyn, Reif, Susan S., Sullivan, Kristen   +3 more
core   +1 more source

Mapping Satellite Glial Cell Heterogeneity Reveals Distinct Spatial Organization and Implies Functional Diversity in the Dorsal Root Ganglion

Advanced Science, EarlyView.
Four distinct satellite glial cell subtypes are identified in mouse dorsal root ganglia using single‐cell RNA sequencing and spatial validation. These subtypes show unique marker profiles and anatomical distributions. Human dorsal root ganglia display layered perisomatic organization with differential marker expression.
Ole Andreas Ahlgreen, Mads Würgler Hansen, Jonas Baake, Thomas Engelbrecht Hybel, Rachele Rossi, Xin Lai, Ishwarya Sankaranarayanan, Johanne Amalie Pold, Lin Lin, Line Reinert, Søren Riis Paludan, Theodore John Price, Lone Tjener Pallesen, Christian Bjerggaard Vægter   +13 more
wiley   +1 more source

Reply to Datta, "Is static or cidal antibiotic falsifiable?" [PDF]

Antimicrob Agents Chemother
Spellberg B, Wald-Dickler N, Holtom P, Meyer-Sautter P, Camp A, Diaz AD, Buhamad R, Vazquez ASM, Aguirre-Garcia GM, Stanton M, Butler-Wu SM, Chiu I, Ergenc Z, Bhoojhawon G, Murri R, Maraolo AE, Cabanilla G, Riccardi N, Tshisevhe V, Behenna C, Williams KS, Kufel WD, Wojciaczyk N, Pimentel BV, Muyidi A, Costa RPL, Motta F, Bortolussi-Courval É, Lee TC, McDonald EG, Ghanem B, Nelson Z.   +31 more
europepmc   +1 more source

Tubule‐Derived IFN‐α Promotes GSDMD‐Mediated Macrophage Pyroptosis to Drive Renal Inflammation and Fibrosis Through JAK2/STAT2 Activation

Advanced Science, EarlyView.
Mao and colleagues uncover a STAT2/IRF9‐dependent signaling axis through which tubular epithelial cell (TEC)‐derived IFN‐α induces gasdermin D (GSDMD)‐mediated pyroptosis in macrophages. This TEC‐macrophage feedback loop amplifies renal inflammation and fibrosis, providing mechanistic insight into the progression of chronic kidney disease and revealing
Yiping Xu, Yating Wang, Siming Jiang, Yi Li, Guanglan Li, Yuchu Liu, Siyuan Li, Yiming Zhou, Qinghua Liu, Yi Zhou, Wei Chen, Hongyu Li, Haiping Mao   +12 more
wiley   +1 more source

"Electronic Pediatrician", a non-machine learning prototype artificial intelligence software for pediatric computer-assisted pathophysiologic diagnosis - general presentation. [PDF]

World J Methodol
Drăgoi AL, Nemeș RM.
europepmc   +1 more source

Structure‐Based Development of Ultra‐Broad‐Spectrum 3C‐Like Protease Inhibitors

Advanced Science, EarlyView.
This study provides an in‐depth analysis of the substrate binding pocket of 3CLpros across all coronavirus species using bioinformatics and structural insights, revealing the critical impact of S2/S4 subsite diversity on the broad‐spectrum activity of approved therapeutics.
Haixia Su, Tianqing Nie, Guofeng Chen, Muya Xiong, Yumin Zhang, Guoqing Wu, Mengyuan You, Hang Xie, Jian He, Yanchao Xiong, Hangchen Hu, Wenfeng Zhao, Minjun Li, Gengfu Xiao, Leike Zhang, Yechun Xu   +15 more
wiley   +1 more source

Determinants of hepatitis C virus treatment completion among Los Angeles County residents. [PDF]

BMC Infect Dis
Hernandez-Tamayo C, Stafylis C, Bhardwaj L, Shah RK, Becerra T, Bruce D, Saini R, Saremi N, Thomas I, Manansala-Tan K, Vij AP, Li A, Sudeep N, Gizamba J, Hosseini B, Navarro S, Ufret-Rivera S, Farias AJ, Klausner JD.   +18 more
europepmc   +1 more source

Aceso: Journal of the Boston University School of Medicine Historical Society [PDF]

, 2015
Beazley, Robert M., Brust, James S., Ettien, A'Llyn, Eversole, Theodore W., O'Brien, Michael J., Peng, Teng J.   +5 more
core   +1 more source

The Analysis of Medical Malpractice Litigation Related to Diagnosis of Headache in Japan: Mitigating Medicolegal Risks for Primary Care Physicians. [PDF]

Cureus
Ohira M, Sumioka R, Takao M.
europepmc   +1 more source