Results 81 to 90 of about 162,888 (305)

Cutaneous Phosphorylated Alpha‐Synuclein in Lewy Body Dementia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine the test performance of cutaneous phosphorylated alpha‐synuclein (P‐SYN) in dementia with Lewy bodies (DLB), individuals with reduced Montreal Cognitive Assessment (MoCA) and healthy controls. Methods This is the first subgroup analysis of the Synuclein‐One study, a prospective, blinded study evaluating P‐SYN detection ...
Christopher H. Gibbons, Todd Levine, Charles H. Adler, Bailey Bellaire, Ningshan Wang, Pinky Agarwal, Georgina M. Aldridge, Alexandru Barboi, Daniel Claassen, Virgilio G. H. Evidente, Douglas Galasko, Alejandra Gonzalez‐Duarte, Ramon Gil, Mark Gudesblatt, Stuart H. Isaacson, Horacio Kaufmann, Pravin Khemani, Rajeev Kumar, Guillaume Lamotte, Andy J. Liu, Nikolaus R. McFarland, Mitchell G. Miglis, Adam Reynolds, Gregory A. Sahagian, Marie‐Helene Saint‐Hilaire, Julie B. Schwartzbard, Wolfgang Singer, Michael J. Soileau, Steven Vernino, Patricio Millar Vernetti, Oleg Yerstein, Roy Freeman   +31 more
wiley   +1 more source

Implementation of a Large System-Wide Hepatitis C Virus Screening and Linkage to Care Program for Baby Boomers. [PDF]

, 2017
BackgroundWe implemented and evaluated a large health system-wide hepatitis C virus (HCV) screening and linkage to care program for persons born between 1945 and 1965 ("baby boomers").MethodsAn electronic health record (EHR) clinical decision support ...
Castrejón, Mariana, Chew, Kara W, Humphries, Romney, Javanbakht, Marjan, Klausner, Jeffrey D, Saab, Sammy   +5 more
core   +1 more source

Role of biomarkers in predicting disease severity in acute dengue and SARs-CoV-2-Infected patients

BMC Infectious Diseases
Purpose The early stages of both dengue infection and COVID-19 can present similarly with acute febrile illness or influenza-like symptoms, and individuals with initially mild disease may progress to more severe symptoms.
Eakkawit Yamasmith, Jennifer D. Kinslow, Michael G. Berg, Gavin A. Cloherty, James N. Moy, Alan L. Landay, Yupin Suputtamongkol, Wiwit Tantibhedhyangkul   +7 more
doaj   +1 more source

P-899. Strong Hearts Program: Results of a Novel Primary-Care Based Chagas Disease Care Program in East Boston, MA, 2017-2023

Open Forum Infectious Diseases
Background Chagas disease is a neglected parasitic infection that affects ∼300,000 people in the US, with a prevalence of ∼49 per 100,000 in Massachusetts, USA. Untreated Chagas disease leads to irreversible cardiac morbidity and death in 20-30% of cases,
J. J. Huerta, Ashley Maldonado, C. Milliren, Jillian Hertig, Katherine Collins, Jim Gomes, A. Salazar, Daniel Bourque, Natasha S. Hochberg, David H. Hamer, Leonard Levin, Jaime Gallegos Salazar, Elizabeth D. Barnett, Juan Huanuco, Jennifer Manne-Goehler, Julia R Köhler   +15 more
semanticscholar   +1 more source

Patterns of Postictal Abnormalities in Relation to Status Epilepticus in Adults

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Abnormalities on peri‐ictal diffusion‐weighted magnetic resonance imaging (DWI‐PMAs) are well‐established for patients with status epilepticus (SE), but knowledge on patterns of DWI‐PMAs and their prognostic impact is sparse. Methods This systematic review and individual participant data meta‐analysis included observational studies ...
Andrea Enerstad Bolle, Silvana Sarria‐Estrada, Thomas Bonduelle, Bertram Daniel Dynesen, Manuel Toledo, Zhu Chung Che, Kjell Heuser, Anastasios Chatzikonstantinou, Jérôme Aupy, Udaya Seneviratne, Estevo Santamarina Perez, Christoph Patrick Beier   +11 more
wiley   +1 more source

Real‐World Performance of CSF Kappa Free Light Chains in the 2024 McDonald Criteria

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Kappa free light chains (KFLCs) in the cerebrospinal fluid (CSF) have a similar performance to CSF‐restricted oligoclonal bands (OCB) for multiple sclerosis (MS) diagnosis. To help with implementation, we set out to resolve several remaining uncertainties: (1) performance in a real‐world cohort and the 2024 McDonald criteria; (2 ...
Maya M. Leibowitz, Ryan Cooper, Stefania Kaninia, Kathryn I. Challis, Will Greenway, Maria Bonello, Mahmoud Elbahnasawi, Deborah T. Shode, Dominika Gajdasik, Victor Iliev, Alison M. E. Whitelegg, Ian Galea   +11 more
wiley   +1 more source

Co-producing healthcare in a volume vs. value-based healthcare system: perspective of a parent of a patient and a health professions’ educator [PDF]

, 2019
The Institute for Healthcare Improvement’s Triple Aim framework represents an approach to optimizing a health system’s performance by focusing on improving the patient experience of care, improving the health of populations, and reducing healthcare costs.
Caron, Rosemary M.
core   +3 more sources

Applying an Ethical Lens to the Treatment of People With Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The practice of neurology requires an understanding of clinical ethics for decision‐making. In multiple sclerosis (MS) care, there are a wide range of ethical considerations that may arise. These involve shared decision‐making around selection of a disease‐modifying therapy (DMT), risks and benefits of well‐studied medications in comparison to
Methma Udawatta, Farrah J. Mateen
wiley   +1 more source

Recurrence, Readmission, and Key Mortality Predictors in Patients with Carbapenem-Resistant Enterobacterales Infections

Diagnostics
Background: Carbapenem-resistant Enterobacterales (CRE) are designated by the World Health Organization as critical-priority pathogens. While global outcomes are well documented, regional data from the Middle East remain limited.
Bashayer Mohammed Alshehail, Marwan Jabr Alwezzeh, Hussain Humaid Almalki, Amani Alnimr, Haytham Wali, Zainab Al Jamea, Abdullatif S. Al Rashed, Mashael Alhajri, Hawra Abdulwahab Abdulaal, Lujain Ali Alanbari, Yazed S. Alsowaida, Abdullah Alamri, Sharifah Almuthen, Faten Azaiez, Saeed Alzahrani, Nawaf Zakari, Jaber Asiri, Wafa Alanazi, Mohanad Bakkar, Abdulaziz Alfifi, Omar Alzuwayed, Aiman El-Saed, Salma AlBahrani   +22 more
doaj   +1 more source

Precision Medicine: Changing the way we think about healthcare

Clinics, 2018
Health care has changed since the decline in mortality caused by infectious diseases as well as chronic and non-contagious diseases, with a direct impact on the cost of public health and individual health care.
Gustavo Rosa Gameiro, Viktor Sinkunas, Gabriel Romero Liguori, José Otavio Costa Auler-Júnior   +3 more
doaj   +1 more source