Results 91 to 100 of about 1,250,507 (353)

Diagnosis and Treatment of Infectious Enteritis in Adult Ruminants. [PDF]

, 2018
Infectious enteritis in adult ruminants is often a result of 1 or more viral, bacterial, or parasitic pathogens. Diagnosis of etiologic agents causing enteritis is important when considering herd implications and zoonotic potential of some etiologies ...
Chigerwe, Munashe, Heller, Meera C
core   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

Risk factors for recurrence in patients with Clostridium difficile infection due to 027 and non-027 ribotypes [PDF]

, 2018
Objectives: Our objective was to evaluate factors associated with recurrence in patients with 027+ and 027– Clostridium difficile infection (CDI). Methods: Patients with CDI observed between January and December 2014 in six hospitals were consecutively ...
Aceti, A., Andreoni, M., Antonelli, G., Carfagna, P., Cauda, R., Delle Rose, D., Falcone, M., Fantoni, M., Farcomeni, A., Fontana, C., Goldoni, P., Iraci, F., Mastroianni, C., Murri, R., Petrosillo, N., Raponi, G., Sanguinetti, M., Santino, I., Tiseo, G., Venditti, M.   +19 more
core   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

Practical Recommendations in the Treatment of Acute and Chronic Life-Threatening Infectious Diseases in Patients with Acute Hepatic Porphyria

Metabolites
Background: Acute hepatic porphyrias (AHPs) represent inherited metabolic disorders of the heme biosynthesis pathway, leading to neurological and systemic impairment. Despite the presence of well-recognized chronic symptoms and signs, acute neurological,
Bruno de Mattos Lombardi Badia, Paulo de Lima Serrano, João Paulo Barile, Daniel Delgado Seneor, Patrícia Marques Mendes, Renan Brandão Rambaldi Cavalheiro, Kaliny Oliveira Peixoto, Igor Braga Farias, Roberta Ismael Lacerda Machado, Wladimir Bocca Vieira de Rezende Pinto, Acary Souza Bulle Oliveira, Paulo Sgobbi   +11 more
doaj   +1 more source

Mycobacterium tuberculosis Bacteremia in HIV-negative Patients

Journal of the Formosan Medical Association, 2007
Limited information exists about the epidemiologic characteristics of HIV-negative patients with Mycobacterium tuberculosis bacteremia (MTB). Methods: We retrospectively surveyed tuberculosis (TB) cases reported at National Taiwan University Hospital ...
Yu-Shin Chiu, Jann-Tay Wang, Shan-Chwen Chang, Jih-Luh Tang, Shih-Chi Ku, Chien-Ching Hung, Po-Ren Hsueh, Yee-Chun Chen   +7 more
doaj   +1 more source

The potential role of pneumococcal conjugate vaccine in reducing acute respiratory inflammation in community-acquired pneumococcal pneumonia

Journal of Biomedical Science, 2020
Background Pneumococcal conjugate vaccine (PCV) reduces both invasive pneumococcal disease (IPD) and other pneumococcal infections worldwide. We investigated the impact of stepwise implementation of childhood PCV programs on the prevalence of ...
Ching-Fen Shen, Shih-Min Wang, Hsin Chi, Yi-Chuan Huang, Li-Min Huang, Yhu-Chering Huang, Hsiao-Chuan Lin, Yu-Huai Ho, Chao A. Hsiung, Ching-Chuan Liu, Taiwan Pediatric Infectious Disease Alliance   +10 more
doaj   +1 more source

Housing, management and health in Swedish dairy calves [PDF]

, 2004
This thesis discusses the results of an observational study conducted in dairy herds in the south-western Sweden and a questionnaire survey of dairy herds done throughout Sweden.
Lundborg, Karin
core  

Does Porphyromonas gingivalis truly inhibit the oral carcinogenesis?

Molecular Oncology, EarlyView.
 
Chen‐xi Li, Zhong‐cheng Gong
wiley   +1 more source

Ruxolitinib plus standard of care in severe hospitalized adults with severe fever with thrombocytopenia syndrome (SFTS): an exploratory, single-arm trial

BMC Medicine
Background Severe fever with thrombocytopenia syndrome (SFTS) is an emerging tick-borne infectious disease, and its morbidity and mortality are increasing. At present, there is no specific therapy available.
Sai Wen, Nannan Xu, Lianhui Zhao, Lulu Yang, Hui Yang, Caiyun Chang, Shanshan Wang, Chunmei Qu, Li Song, Wenlu Zou, Yishan He, Gang Wang   +11 more
doaj   +1 more source