Results 201 to 210 of about 771,612 (309)

Quantifying transmission and immunity dynamics of multiple SARS-CoV-2 variants using models and epidemic data from a highly populated area. [PDF]

PLoS One
Shah MS, Lee J, Pomeroy LW.
europepmc   +1 more source

Biofilm Control by Active Topography with Mucin Coating

Advanced Functional Materials, EarlyView.
This study reports a new antifouling strategy based on a bioinspired design. Mucin coating enhances biofilm control by active topography with beating micron‐sized pillars. Besides the mechanical force of beating pillars, the antibiofilm activities also involve biological factors since mucin coating inhibits swarming motility and c‐di‐GMP synthesis in ...
Zehui Han, Yikang Xu, Huan Gu, Teng Zhang, Dacheng Ren   +4 more
wiley   +1 more source

Complicated enteroenteric intestinal fistula due to Crohn's disease: a rare case report. [PDF]

J Surg Case Rep
Alkhatıb M, Bozkurt H, Ozcan C, Yüksek HH, Reyhan E.   +4 more
europepmc   +1 more source

Photothermal Hydrogel with Mn3O4 Nanoparticles Alleviates Intervertebral Disc Degeneration by Scavenging ROS and Regulating Extracellular Matrix Metabolism

Advanced Functional Materials, EarlyView.
The MPTT‐nanozyme‐hydrogel system (Mn3O4@ChS‐HA) provides a multifunctional therapeutic strategy for intervertebral disc degeneration (IVDD), effectively targeting oxidative stress and enhancing AF repair by restoring extracellular matrix (ECM) and redox homeostasis.
Yangyang Chen, Chan Xue, Feifei Ni, Binwu Hu, Miaoheng Yan, He Zhang, Yuxiang Hu, Xiaoyao Peng, Guangfang Li, Yu Han, Hongjian Liu, Zengwu Shao, Qin Wang, Yulong Wei   +13 more
wiley   +1 more source

Adrenomedullin Therapy for Moderate-to-Severe COVID-19 Pneumonia: Double-Blind Placebo-Controlled Phase 2a Trial. [PDF]

Viruses
Kita T, Ohmagari N, Saito S, Mukae H, Takazono T, Nakada TA, Shimada T, Hirai Y, Shindo Y, Komiya K, Saito A, Yamato M, Homma K, Okamoto M, Yamamoto Y, Mutoh Y, Hasegawa C, Mori N, Nakamura-Uchiyama F, Honda M, Tomii K, Ishii H, Takajo I, Watanabe K, Kitamura K.   +24 more
europepmc   +1 more source

Imaging of Lipid Droplets in Living Cells and Mice with Metabolic Dysfunction‐Associated Steatotic Liver Disease via a Galactose‐Modified Supramolecular Near‐Infrared Fluorescent Glycoprobe

Advanced Functional Materials, EarlyView.
A galactose‐modified supramolecular near‐infrared (NIR) glycoprobe, TCF‐FBN@Gal‐BSA, enables targeted delivery to the liver through the asialoglycoprotein receptor (ASGPR) and facilitates liver‐targeting fluorescence visualization of lipid droplets (LDs) in metabolic dysfunction‐associated steatotic liver disease (MASLD) mice.
Han‐Min Wang, Lei Dong, Qiu‐Lian Hao, Lu‐Lu Sun, Xin‐Rong Li, Yu‐Wei Yuan, Ming‐Ye Tang, Jin Gong, Yi Zang, Jia Li, Tony D. James, Xiao‐Peng He, Hai‐Hao Han   +12 more
wiley   +1 more source

Intraoral Drug Delivery: Bridging the Gap Between Academic Research and Industrial Innovations

Advanced Functional Materials, EarlyView.
Intraoral drug delivery offers a promising route for systemic and localized therapies, yet challenges such as enzymatic degradation, limited permeability, and microbial interactions hinder efficacy. This figure highlights innovative strategies—mucoadhesive materials, enzyme inhibitors, and permeation enhancers—to overcome these barriers.
Soheil Haddadzadegan, Simona Summonte, Fabrizio Ricci, Matthias Sandmeier, Andreas Bernkop‐Schnürch   +4 more
wiley   +1 more source

Incorporating Ethics in Clinical Guidelines in Infectious Diseases: A Scoping Review.

JAMA Netw Open
Yahav D, Nasim A, Shirin N, Armellini M, Zanchi C, Tunali V, Mirandola M, Barac A, Scudeller L, Nagavci B, Paño-Pardo JR, Rodríguez-Baño J, Jamrozik E, Akova M, Righi E.   +14 more
europepmc   +1 more source

Development of a Clostridium Perfringens Challenge Model in Broiler Chickens to Evaluate the Effects of Feed Additives. [PDF]

Pathogens
Kollár A, Selymes K, Tóth G, Szekeres S, Dobra PF, Bárdos K, Ózsvári L, Bata Z, Molnár-Nagy V, Tenk M.   +9 more
europepmc   +1 more source

Bacteria‐Derived Extracellular Vesicle as A “Trojan Horse” for Selective M1 Macrophage‐Targeting in A Multi‐Cellular Entanglement Environment

Advanced Functional Materials, EarlyView.
The temporary transition of macrophages from a pro‐inflammatory phenotype of macrophages (M1) to an anti‐inflammatory phenotype of macrophages (M2) is crucial for tissue repair and regeneration processes. Bacterial outer membrane vesicles (OMVs) are utilized as a “trojan horse” for specific M1 macrophage‐targeting and anti‐inflammatory drug delivery ...
Donglin Cai, Zhelun Li, Wendong Gao, Yuqing Mu, Jiaying Liu, Yufeng Zhang, Xiaohan Mei, Jingjing Quan, Lan Xiao, Yin Xiao   +9 more
wiley   +1 more source