Results 21 to 30 of about 2,285,862 (398)

High burden of untreated syphilis, drug resistant Neisseria gonorrhoeae, and other sexually transmitted infections in men with urethral discharge syndrome in Kampala, Uganda

BMC Infectious Diseases, 2022
Objectives Prompt diagnosis and treatment of sexually transmitted infections (STIs) are essential to combat the STI epidemic in resource-limited settings.
Matthew M. Hamill, Annet Onzia, Tza-Huei Wang, Agnes N. Kiragga, Yu-Hsiang Hsieh, Rosalind Parkes-Ratanshi, Ethan Gough, Peter Kyambadde, Johan H. Melendez, Yukari C. Manabe   +9 more
doaj   +1 more source

Is neglect of self-clearance biasing TB vaccine impact estimates?

BMJ Global Health, 2023
Background Mathematical modelling has been used extensively to estimate the potential impact of new tuberculosis vaccines, with the majority of existing models assuming that individuals with Mycobacterium tuberculosis (Mtb) infection remain at lifelong ...
Richard White, Jon Emery, Rebecca A Clark, Nicky McCreesh, Rein M G J Houben, Danny Scarponi, Chathika Krishan Weerasuriya   +6 more
doaj   +1 more source

Plasmodium falciparum genotypes in matched peripheral, placental and umbilical cord blood in an area characterised by unstable malaria transmission in eastern Sudan

Heliyon, 2017
Background: There are few published studies on Plasmodium falciparum genotypes in peripheral, placental and umbilical cord blood in areas characterised by unstable malaria transmission.
Omar E. Fadlelseed, Maha E. Osman, Nahla M. Shamseldin, Amar B. Elhussein, Ishag Adam   +4 more
doaj   +1 more source

Human organs-on-chips for disease modelling, drug development and personalized medicine

Nature reviews genetics, 2022
The failure of animal models to predict therapeutic responses in humans is a major problem that also brings into question their use for basic research.
D. Ingber
semanticscholar   +1 more source

Risk-Taking Behavior and Its Impact on Treatment, Vaccination and Diagnosing [PDF]

, 2015
We present results from two recent mathematical biology studies that address the effect of risk-taking behavior on epidemic models. We show that when risk-taking prevails over riskavoidance, it is possible to show a detrimental and counterintuitive ...
Maxin, Daniel
core   +4 more sources

What are the pathways between poverty and malaria in sub-Saharan Africa? A systematic review of mediation studies

Infectious Diseases of Poverty, 2023
Background Malaria remains a major burden in sub-Saharan Africa (SSA). While an association between poverty and malaria has been demonstrated, a clearer understanding of explicit mechanisms through which socioeconomic position (SEP) influences malaria ...
Solomon T. Wafula, Theresa Habermann, Mara Anna Franke, Jürgen May, Dewi Ismajani Puradiredja, Eva Lorenz, Johanna Brinkel   +6 more
doaj   +1 more source

Biological Significance of Dual Mutations A494D and E495K of the Genotype III Newcastle Disease Virus Hemagglutinin-Neuraminidase In Vitro and In Vivo

Viruses, 2022
As a multifunctional protein, the hemagglutinin-neuraminidase (HN) protein of Newcastle disease virus (NDV) is involved in various biological functions.
Xiaolong Lu, Tiansong Zhan, Kaituo Liu, Yu Chen, Zenglei Hu, Jiao Hu, Min Gu, Shunlin Hu, Xiaoquan Wang, Xiaowen Liu, Xiufan Liu   +10 more
doaj   +1 more source

Infectious disease pandemic planning and response: Incorporating decision analysis

PLoS Medicine, 2020
Freya Shearer and co-authors discuss the use of decision analysis in planning for infectious disease pandemics.
F. Shearer, Rob Moss, J. McVernon, J. Ross, J. McCaw   +4 more
semanticscholar   +1 more source

Tuberculosis diagnostics and biomarkers: needs, challenges, recent advances, and opportunities [PDF]

, 2012
Tuberculosis is unique among the major infectious diseases in that it lacks accurate rapid point-of-care diagnostic tests. Failure to control the spread of tuberculosis is largely due to our inability to detect and treat all infectious cases of pulmonary
Alexandre Harari, Alimuddin Zumla, Armand, Axelsson-Robertson, Banada, Ben Marais, Betsou, Blakemore, Boehme, Boehme, Cattamanchi, Chow, Cuevas, Cuevas, Cuevas, Cuevas, Diel, Dowdy, Dye, European Centre for Disease Prevention and Control, Ferrara, Giovanni-Batista Migliori, Giuseppe Pantaleo, Green, Harari, Helb, Helen Cox, Hillemann, Hohn, Ibrahim Abubakar, Jeremiah Chakaya, John, Justin O’Grady, Karin Weyer, Keeler, Kemp, Kunnath-Velayudhan, Lawn, Lawn, Lawn, Lawn, Lawn, Lemaire, Lin, Ling, Liu, Long, Lucica Ditui, Lynn Zijenah, Mann, Marais, Marais, Marais, Marais, Marco Schito, Markus Maeurer, Marlowe, Martin P. Grobusch, Martina Casenghi, Matthew Bates, McNerney, Michael Hoelscher, Michel Pletschette, Minion, Moore, Morris, Mwaba, Nathan Ford, Nathanson, National Institute for Health and Clinical Excellence, Nicol, Nicol, Oberhelman, O’Grady, Peter, Peter Mwaba, Peter S. Kim, Rifat Atun, Rose, Ruth McNerney, S. Bertel Squire, Samana Schwank, Sester, Shah, Soumya Swaminathan, Squire, Squire, Steingart, Steingart, Steingart, Steve Lawn, Storla, Temple, Theron, Timothy D. Mchugh, Treatment Action Group, Tully, Vadwai, Van Rie, van Wyk, Wallis, Walzl, Weyer, Wilson, World Health Organization, World Health Organization, World Health Organization, World Health Organization, World Health Organization, World Health Organization, World Health Organization, World Health Organization, World Health Organization, Wright, Wright, Zar, Ziad Memish, Zumla, Zumla   +118 more
core   +2 more sources

Travel restrictions and infectious disease outbreaks

Journal of Travel Medicine, 2020
Background A key purpose of the IHR is to prevent unwarranted interruptions to trade and travel during large and/or transnational infectious disease outbreaks. Nevertheless, such outbreaks continue to disrupt the travel industry.
R. Vaidya, A. Herten-Crabb, J. Spencer, S. Moon, L. Lillywhite   +4 more
semanticscholar   +1 more source