Results 91 to 100 of about 6,892,369 (255)

The genetics of infectious disease susceptibility: has the evidence for epistasis been overestimated? [PDF]

, 2013
Interactions amongst genes, known as epistasis, are assumed to make a substantial contribution to the genetic variation in infectious disease susceptibility, but this claim is controversial.
Ebert, Dieter, Dieter Ebert, Hall, Matthew, Matthew D Hall, Hall, Matthew D.   +4 more
core   +1 more source

Optical Detection of Cellular Signals at Material Interfaces

Advanced Healthcare Materials, EarlyView.
Emerging functional materials are transforming optical detection of cellular signals. This review highlights optical techniques that exploit the unique optical properties of diverse materials to detect and quantify cellular electrical, chemical, and mechanical signals, and discusses key opportunities and challenges.
Xuchen Ren, Jitong Ren, Zixin Zhang, Koney Eungkon Kim, Francis L. Hong, Yuecheng Peter Zhou   +5 more
wiley   +1 more source

Infectious disease outbreak and trade policy formulation [PDF]

This paper provides a framework to understand why a country might resort to a policy like an import ban when at risk from infectious disease outbreak overseas.
Sheikh Shahnawaz
core  

Tuberculosis transmission attributable to close contacts and HIV status, Malawi. [PDF]

, 2006
We conducted the first molecular study of tuberculosis (TB) to estimate the role of household contact and transmission from HIV-positive putative source contacts (PSCs) in a high HIV-prevalence area.
Yates, Malcolm D, Traore, Hamidou, Judith R. Glynn, Hamidou Traore, Michael Mwenebabu, Fine, Paul E.M., Glynn, Judith R., Mwenebabu, M, Glynn, Judith R, Crampin, Amelia C, Mwenebabu, Michael, Mwaungulu, Lorren, Drobniewski, FD, Amelia C. Crampin, Mwaungulu, L, Sian Floyd, Fine, Paul EM, Traoré, H, Paul E.M. Fine, Crampin, Amelia C., Chaguluka, SD, Floyd, Sian, Yates, Malcolm D., Chaguluka, Steven D, Lorren Mwaungulu, Steven D. Chaguluka, Malcolm D. Yates, Drobniewski, Francis, Glynn, JR, Yates, MD, Crampin, AC, Chaguluka, Steven D., Francis Drobniewski, Fine, PEM, Floyd, S   +34 more
core   +1 more source

PLL‐g‐HPA Hydrogel Microneedles Loaded With Rhoifolin Target Macrophages to Alleviate Fibroblast Senescence for Diabetic Wound Healing

Advanced Healthcare Materials, EarlyView.
Diabetic wound healing is hindered by a pathological crosstalk wherein elevated IL‐11 induces M1 macrophage polarization, leading to IL‐1β/IL‐6 release and subsequent fibroblast senescence via RAS/p38MAPK/p53/E2F1 signaling. Here, we develop a Gel@M‐Rho microneedle patch that delivers rhoifolin‐loaded, macrophage membrane‐coated nanoparticles to target
Jiewen Liao, Lin Gan, Li Lu, Lizhi Ouyang, Yuan Xiong, Fawwaz Al‐Smadi, Guandong Dai, Mohammad‐Ali Shahbazi, Bobin Mi, Mengfei Liu, Guohui Liu   +10 more
wiley   +1 more source

Risk of foot-and-mouth disease spread due to sole occupancy authorities and linked cattle holdings [PDF]

, 2012
Livestock movements in Great Britain are well recorded, have been extensively analysed with respect to their role in disease spread, and have been used in real time to advise governments on the control of infectious diseases.
O'Hare, Anthony, Orton, R., Kao Rowland R., Colin P D Birch, Kao, Rowland R, Orton, Richard, Bessell, Paul R, Birch, Colin P. D., O'Hare, A., Colin P. D. Birch (126488), Richard J Orton, Orton Richard J., Orton, Richard J., Anthony O'Hare (116908), O'Hare Anthony, Paul R Bessell, Kao, R., Bessell, Paul R., Kao, Rowland R., Rowland R Kao, Bessell Paul R., Bessell, P., Rowland R. Kao (116940), Richard J. Orton (116918), Paul R. Bessell (169949), Birch Colin P. D., Anthony O'Hare, Birch, Colin P D   +27 more
core   +1 more source

Climate Change and Infections on the Move in North America

Infection and Drug Resistance, 2021
Naomi Hauser,1,2 Kathryn C Conlon,2– 4 Angel Desai,1 Leda N Kobziar5 1Department of Medicine, Division of Infectious Disease, University of California Davis Health, Sacramento, CA, USA; 2Climate Adaptation Research Center, University of California, Davis,
Hauser N, Conlon KC, Desai A, Kobziar LN
doaj  

Chemical Strategies for Multistimuli Responsive Dynamic Covalent Materials in Regenerative Medicine

Advanced Healthcare Materials, EarlyView.
Multistimuli responsive dynamic covalent materials integrate reversible chemistry with the complex chemical, mechanical, and biochemical cues of regenerative environments. This review highlights chemical strategies based on orthogonal dynamic bonds, multicomponent networks, and hierarchical architectures to regulate mechanics, degradation, and ...
Saurabh Joshi, Matthew B. Baker, Dominik Schauenburg   +2 more
wiley   +1 more source

Experimental medicine study with stabilised native-like HIV-1 Env immunogens drives long-term antibody responses, but lacks neutralising breadthResearch in context

EBioMedicine
Summary: Background: We report findings from an experimental medicine study of rationally designed prefusion stabilised native-like HIV envelope glycoprotein (Env) immunogens, representative of global circulating strains, delivered by sequential ...
Katrina M. Pollock, Hannah M. Cheeseman, Leon R. McFarlane, Suzanne Day, Monica Tolazzi, Hannah L. Turner, Jennifer Joypooranachandran, Katsiaryna Shramko, Stefania Dispinseri, Philipp Mundsperger, Ilja Bontjer, Nana-Marie Lemm, Sofia Coelho, Maniola Tanaka, Tom Cole, Bette Korber, Dietmar Katinger, Quentin J. Sattentau, Andrew B. Ward, Gabriella Scarlatti, Rogier W. Sanders, Robin J. Shattock   +21 more
doaj   +1 more source

ACUTE TOXOPLASMOSIS IN A BREASTFED INFANT WITH POSSIBLE TRANSMISSION BY WATER

Revista do Instituto de Medicina Tropical de São Paulo, 2015
Toxoplasma gondii transmission via breastfeeding has been discussed; however, no cases have been confirmed to date. This article describes a case of acute toxoplasmosis diagnosed in a mother and her six-month-old breastfed infant.
Jaqueline Dario CAPOBIANGO, Regina MITSUKA-BREGANÓ, Thais Cabral MONICA, Fernanda Pinto FERREIRA, Edna Maria Vissoci REICHE   +4 more
doaj   +1 more source