Results 151 to 160 of about 3,979,167 (303)

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

open access: yesFEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

open access: yesFEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen   +8 more
wiley   +1 more source

A Case Report of Unusual Diagnosis of Melioidosis in a Non-Traveler: Implications for Transmission and Diagnosis

open access: yesInfection and Drug Resistance
Chenliang Fan,1 Xiaosi Li,1 Baizhi Pi,2 Jiasheng Wu,3 Heping Shen,3 Yumiao Guo,3 Xiaoyan Wu1 1Department of Laboratory Medicine, the Second Affiliated Hospital of Jiaxing University, Jiaxing, 314001, People’s Republic of China; 2Department of Intensive ...
Fan C   +6 more
doaj  

CDC infectious diseases laboratory test directory, Version 12.8

open access: yes
This document was created under National Center for Emerging and Zoonotic Diseases/ Office of Infectious Diseases (NCEZID/OD). The printed version of CDC's Infectious Diseases Laboratory Test Directory contains information that is current as of April 13,

core  

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

open access: yesAging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho   +4 more
wiley   +1 more source

Phase I, Randomized, Double-Blind, Placebo-Controlled Trial Investigating the Safety, Tolerability, and Pharmacokinetics of BS1801 in Healthy Chinese Adult Subjects

open access: yesDrug Design, Development and Therapy
Guiling Chen,1,* Guoping Sheng,1,* Kaiqi Wu,1 Tinghan Jin,1 Qi Jiang,1 Tong Guo,1 Yifan Chen,2 Hanwei Yin,3 Guozhou Zhang,3 Zhenwei Shen,1 Huihui Zeng3 1Shulan (Hangzhou) Hospital, Shulan International Medical College, Zhejiang Shuren ...
Chen G   +10 more
doaj  

Building National Wastewater Surveillance for Infectious Diseases in the United States. [PDF]

open access: yesEmerg Infect Dis
Yoder JS   +5 more
europepmc   +1 more source

2014 CDC infectious diseases laboratory test directory, version 6.0

open access: yes
This document was created under National Center for Emerging and Zoonotic Diseases/ Office of Infectious Diseases (NCEZID/OD). The printed version of CDC's Infectious Diseases Laboratory Test Directory contains information that is current as of November ...

core  

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