Results 31 to 40 of about 2,133,431 (349)
Hepcidin and Host Defense against Infectious Diseases. [PDF]
Hepcidin is the master regulator of iron homeostasis in vertebrates. The synthesis of hepcidin is induced by systemic iron levels and by inflammatory stimuli.
Ganz, Tomas+3 more
core +1 more source
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali+3 more
wiley +1 more source
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi+3 more
wiley +1 more source
AI-Based Decadal Predictive Analysis of Twenty Infectious Diseases in China with an Improved BSTS-MCMC Model [PDF]
This study embarks on a comprehensive exploration of the decadal trends and future trajectories of twenty distinct infectious diseases in China from 1998 to 2021. A refined Hybrid Bayesian Structural Time Series (BSTS)-Markov Chain Monte Carlo (MCMC) model is employed, intertwining with Long Short-Term Memory (LSTM) networks to dissect intricate ...
arxiv
Climate change and water-related infectious diseases [PDF]
Background: Water-related, including waterborne, diseases remain important sources of morbidity and mortality worldwide, but particularly in developing countries.
Heaviside, Clare+2 more
core +1 more source
Notification of Infectious Diseases [PDF]
n ...
Hy. Tomkins, E.M. Shirtliff
openaire +3 more sources
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Antimicrobial Stewardship in Daily Practice: Managing an Important Resource
Antimicrobial stewardship is a recent concept that embodies the practical, judicious use of antimicrobials to decrease adverse outcomes from antimicrobials while optimizing the treatment of bacterial infections to reduce the emergence of resistant ...
Nicole Le Saux+1 more
doaj +1 more source
A Dynamic Model for Infectious Diseases: The Role of Vaccination and Treatment [PDF]
Understanding dynamics of an infectious disease helps in designing appropriate strategies for containing its spread in a population. Recent mathematical models are aimed at studying dynamics of some specific types of infectious diseases. In this paper we propose a new model for infectious diseases spread having susceptible, infected, and recovered ...
arxiv +1 more source