Results 61 to 70 of about 27,870 (242)

Aptamer‐Based Delivery Systems for VEGF and NGF Modulation in Ocular Therapies

Advanced Healthcare Materials, EarlyView.
Aptamer‐based delivery systems targeting NGF and VEGF hold significant potential for precise and sustained treatment of complex diseases affecting both the anterior and posterior segments of the eye. This review critically summarizes current strategies for NGF and VEGF delivery as well as VEGF sequestration, providing a clinical perspective on how ...
Nadine Best, Gizem Karabiyik, Gerd Geerling, Sarah Barbara Zwingelberg, Gregor Lang, Martin Humenik   +5 more
wiley   +1 more source

Isolation of Acanthamoeba isolates belonging to T2, T3, T4 and T7 genotypes from environmental samples in Ankara, Turkey [PDF]

, 2004
Acanthamoeba keratitis is a blinding infection that is becoming increasingly important in human health. Early diagnosis is a prerequisite for successful treatment and requires identification of Acanthamoeba at the genotypic level.
Jayasekera, S., Khan, Naveed Ahmed, Kiliç, A., Sissons, J., Tanyuksel, M.   +4 more
core  

Distribution of infectious keratitis in a tertiary hospital in Brazil [PDF]

, 2013
PURPOSE: To investigate the seasonality of infectious keratitis in a tertiary hospital in Brazil. METHODS: Charts from the Ocular Microbiology Laboratory of the Department of Ophthalmology of the Federal University of São Paulo were reviewed from 2005 to
Freitas, Denise de, Hirai, Flávio Eduardo, Hofling-Lima, Ana Luisa, Marujo, Fábio Iglesias, Sato, Elcio Hideo, Yu, Maria Cecília Zorat   +5 more
core   +3 more sources

Microbiological Profile of Infectious Keratitis in a Tertiary Care Hospital

Journal of Marine Medical Society
Background: Microbial keratitis is a major preventable cause of visual impairment. In developed countries viral infections are the leading cause of corneal ulcer whereas bacteria and fungi attributes to maximum number of cases in the developing countries.
Alisha Sharma, Alok Sati, Puneet Bhatt, Sandeep Ninawe, Pooja Mahajan, Ankita Patel, Ashish Bahal   +6 more
doaj   +1 more source

N, S Co‐Doped Carbon Quantum Dots‐Riboflavin Composite Photosensitizers for Enhanced Iontophoresis‐Assisted Corneal Cross‐Linking

Advanced Science, EarlyView.
This study explores the use of N, S co‐doped carbon quantum dots (NS‐CQDs) as carriers for riboflavin, creating NS‐CQDs‐RF composite photosensitizers. These composites improve riboflavin absorption, enhance ROS generation efficiency, and preserve corneal epithelium integrity.
Tinghong Xu, Yong Liu, Wenjing Zhang, Qiuruo Jiang, Yi Jin, Liangzheng Lin, Lumeng Wang, Zhanhao Gu, Mimi Lin, Shihao Chen   +9 more
wiley   +1 more source

Ceratites microbianas relacionadas a lente de contato [PDF]

, 2008
PURPOSE: Contact lens-associated microbial keratitis is a severe condition with sight-threatening potential and increasing incidence. Information regarding the etiological agents is essential in guiding management and may vary geographically.
Hofling-Lima, Ana Luisa, Moriyama, Aline Silveira   +1 more
core   +3 more sources

Case of isolated Rhizobium radiobacter contact lens-related infectious keratitis: A plant microbe now emerging as a human pathogen

American Journal of Ophthalmology Case Reports, 2019
Purpose: To report a case of contact lens-related infectious keratitis caused by the Gram-negative plant pathogen Rhizobium radiobacter. Observations: A 26-year old lady with history of contact lens use presented with three weeks history of right eye ...
Beau J. Fenner, Ashish Kumar, Nicholas Y.Q. Tan, Marcus Ang   +3 more
doaj   +1 more source

MG53 Coordinates Macrophage Polarization and Neuroimmune Coupling to Promote Corneal Nerve Regeneration via the MPEG1–MVP–STAT6 Axis

Advanced Science, EarlyView.
Corneal nerve regeneration is critical to corneal wound healing processes. The current study reveals a novel role of MG53 in promoting corneal nerve regeneration after alkali induced injury. Mechanistically, MG53 enters macrophages via its receptor, MPEG1, promotes MVP K63 ubiquitination, and triggers STAT6 induced repair‐related genes expression ...
Peng Chen, Zhentao Zhang, Lilian Sakai, Yanping Xu, Luxi Zhang, Han Ye, William Sollenberger, Takahide Ikeda, Zhiyu Yan, Keerthika Sathish, Usman Alizai, Haitao Wen, Timothy M. Pawlik, Heather L. Chandler, Hua Zhu   +14 more
wiley   +1 more source

Fungal keratitis among inpatients with corneal ulcers in Thai Binh, Vietnam: A retrospective observational study

Asian Journal of Medical Sciences
Background: Infectious keratitis can be caused by bacteria, fungi, and viruses. Fungi are a common pathogen, especially in developing countries like India, Nepal, and Bangladesh where the prevalence ranges from 20% to 60%.
Nguyen Thi Anh Van , Pham Ngoc Bich , Bui Thi Ngoc Ha , Nguyen Thu Huong   +3 more
doaj   +1 more source

Deep Sequential Feature Learning in Clinical Image Classification of Infectious Keratitis

Engineering, 2021
Infectious keratitis is the most common condition of corneal diseases in which a pathogen grows in the cornea leading to inflammation and destruction of the corneal tissues.
Yesheng Xu, Ming Kong, Wenjia Xie, Runping Duan, Zhengqing Fang, Yuxiao Lin, Qiang Zhu, Siliang Tang, Fei Wu, Yu-Feng Yao   +9 more
doaj   +1 more source