Results 91 to 100 of about 253,008 (288)

Pharmacoeconomic assessment of urinary tract infections in infants born to mather with pathological pregnancy

Кубанский научный медицинский вестник, 2016
The main problems of neonatal period is infectious pathology. A special place among which is an infection of the urinary system, the incidence of 23%. The main source for infectious pathologies of newborn is the mother.
O. A. Shulakova, K. G. Gurevitch, S. K. Zyryanov   +2 more
doaj  

Pregnant individuals perspectives towards receiving COVID-19 vaccination during their pregnancy: an in-depth qualitative study

Frontiers in Public Health
Introduction Pregnant individuals have an increased risk of severe illness from coronavirus disease 2019 (COVID-19) infection. Vaccination is an effective strategy to prevent severe illness and complications for pregnant individuals. Pregnant individuals
Sanne J. M. Zilver, A. Rietveld, N. Schonewille, P. Bakker, Birit F. P. Broekman, Elisabeth van Leeuwen, C. D. de Groot   +6 more
semanticscholar   +1 more source

TP53BP2 Promotes Placental Autophagy and Preeclampsia via G9a and DNMT1 Cooperatively Modulating E2F1

Advanced Science, EarlyView.
G9a, and DNA Methyltransferase1 (DNMT1) cooperatively modulates E2F1 on the promoter of tumor suppressor p53‐binding protein 2 (TP53BP2) increased autophagy in preeclampsia. TP53BP2 promotes autophagy in trophoblasts through DNA methylation and H3K9me2‐mediated transcriptional regulation.
Nan Jiang, Shaoju Jin, Shaoying Wen, Wen Zeng, Chen Wang, Jingyu Wang, Qingyun Song, Guizhong Li, Pengzhi Yin, Yuhui Liao, Yuee Chai, Huiping Zhang, Shengchao Ma   +12 more
wiley   +1 more source

Caspase‐3/GSDME‐Mediated Trophoblast Pyroptosis and Reciprocal Macrophage Polarization Contribute to Inflammation in Early‐Onset Preeclampsia

Advanced Science, EarlyView.
In trophoblast cells, T/S (TNFα + SM164) activated caspase‐3, which cleaved GSDME to switch apoptosis to pyroptosis, causing cell swelling, membrane rupture, and release of LDH, HMGB1, IL‐1β and IL‐18. These cytokines induced pro‐inflammatory macrophage polarization, which in turn reinforced pyroptotic signaling in trophoblasts, amplifying systemic ...
Baoying Huang, Weinan Deng, Shilei Bi, Yifan Wang, Zhaowei Tu, Lijun Huang, Lili Du, Lizi Zhang, Zhoushan Feng, Wei Sun, Tengfei Liu, Julia Kzhyshkowska, Haibin Wang, Jingsi Chen, Dunjin Chen, Shuang Zhang   +15 more
wiley   +1 more source

Promoting Vaccinations in Pregnancy: Results of a Systematic Literature Review of Italian Initiatives

Vaccines
Pregnant women and infants inherently face heightened susceptibility to complications resulting from infectious diseases. Within these populations, vaccinations offer numerous advantages.
S. Properzi, Maria Stella Sepioni, R. Carestia, Giulia Cervelli, Chiara de Waure   +4 more
semanticscholar   +1 more source

Cell‐Free DNA‐Based Theranostics for Inflammatory Disorders

Advanced Science, EarlyView.
Summary on the dual potential of cfDNA as biomarkers and therapeutic targets for inflammatory disorders. Figure was created with BioRender.com. ABSTRACT Inflammatory disorders are characterized by immune‐mediated inflammatory cascades that can affect multiple organs.
Jiatong Li, Yumei Wang, Xiaoxi Fan, Miao Xu, Jiawen Li, Wenfei Tan, Jianxiang Zhang, Heran Li   +7 more
wiley   +1 more source

[Obstetric care and severe pregnancy complications in Latin America and the Caribbean: an analysis of information from demographic health surveys].

Revista Panamericana De Salud Publica-pan American Journal of Public Health, 2007
OBJECTIVE To compile, consolidate, and analyze information obtained in surveys conducted by the MEASURE DHS [Demographic and Health Surveys] program, concerning obstetric care and pregnancy complications for women in Latin America and the Caribbean, in ...
J. Souza, M. Parpinelli, E. Amaral, J. Cecatti   +3 more
semanticscholar   +1 more source

Migrasomes in Ischemic Stroke: Molecular Landscape and Pathophysiological Impact

Advanced Science, EarlyView.
Multi‐omics profiling of stroke patients exposes systemic molecular fingerprints of immune activation, oxidative stress and metabolic collapse. Complement and coagulation cascade, and cholesterol metabolism emerge as shared functional hallmarks of plasma migrasomes in stroke patients and migrasomes isolated from experimental stroke mice.
Huifen Zhou, Yingying Zhang, Peng Zhou, Haofang Wan, Lingling Li, Bin Xu, Yuping Wan, Yingming Song, Yi Kang, Hongbo Zhang, Min Shi, Qun Hou, Jiehong Yang, Chen Ding, Wei Fu, Buchang Zhao, Haitong Wan   +16 more
wiley   +1 more source

Pregnancy Associated with Systemic Lupus Erythematosus: Immune Tolerance in Pregnancy and Its Deficiency in Systemic Lupus Erythematosus—An Immunological Dilemma

Journal of Immunology Research, 2015
Pregnancy is a physiological condition that requires immune tolerance to the product of conception. Systemic lupus erythematosus (SLE) is a disease with well-represented immune mechanisms that disturb immune tolerance.
Cristina Gluhovschi, Gheorghe Gluhovschi, Ligia Petrica, Silvia Velciov, Adrian Gluhovschi   +4 more
doaj   +1 more source

Modern approaches to improving the eff ectiveness of antibiotic therapy in perinatology: local experience

Качественная клиническая практика, 2019
Premature newborns are group of high risk on development of infectious complications therefore the choice of effective and safe antibacterial therapy is relevant for them.
A. M. Kazanova, S. K. Zyryanov, M. A. Ivzhits, A. N. Kruglov, K. O. Kutsaia, M. S. Chenkurov   +5 more
doaj   +1 more source