Results 91 to 100 of about 1,978,294 (292)

Combined predictors of febrile infectious complications.

, 2022
Combined predictors of febrile infectious complications.
Shu-Cheng Chou (11944443), Cheng-Yuan Hsia (526513), Gar-Yang Chau (425169), Hon-Fan Lai (11944437), Ivy Yenwen Chau (11944440), Hao-Jan Lei (425170), Yi-Chu Kao (11944446)   +6 more
core   +1 more source

LAPTM5 Downregulation‐Driven VAMP8 Phosphorylation Impairs Autophagosome‐Lysosome Fusion and Aggravates Septic Acute Lung Injury

Advanced Science, EarlyView.
LAPTM5 functions as a critical molecular scaffold bridging PGAM5 and VAMP to facilitate PGAM5‐mediated dephosphorylation of VAMP8. This cascade promotes autophagosome‐lysosome fusion, restores impaired autophagic flux, and clears damaged mitochondria, thereby mitigating cellular oxidative stress and systemic inflammation.
Lang Jiang, Qilan Li, Hao Liu, Xuehui Gao, Hongyu Nie, Lang Chen, Mei He, Xuefeng Li, Xiangming Fang, Jiqian Xu, Hao Zhang, Jiahong Xia, You Shang   +12 more
wiley   +1 more source

Challenges of a Pregnancy Gone Wrong: Pregnancy Complications, Illness Perceptions and Distress [PDF]

, 2014
Women with pregnancy complications need to cope with a pregnancy that can have life changing consequences. The objective of this research project was to understand the experience of women who had been diagnosed with a pregnancy complication. The research
Currie, Jane Christina Helen
core  

Hypertensive pregnancy complications and maternal characteristics as predictors of cardiovascular health within ten years after delivery

, 2023
Objective: To identify the combination of maternal characteristics in women with hypertensive disorders of pregnancy (HDP) associated with hypertensive and other cardiovascular diseases (CVDs) within ten years following delivery. The aim is to understand
Laivuori, Hannele, Kivinen, Katja, Laivuori, H, Juha Kere, Heinonen, Seppo, Kajantie, Eero, Kajantie, E, Seppo Heinonen, Kivelä, Anni, Kivela, A, Kivinen, K, Jaaskelainen, T, Eero Kajantie, Anni Kivelä, The FINNPEC Study Group, Hannele Laivuori, Kere, J,, Katja Kivinen, Heinonen, S, Tiina Jääskeläinen, Kere, Juha, Jaaskelainen, Tiina, FINNPEC Study Group, The F. I. N. N. P. E. C. Study   +22 more
core   +1 more source

Lactate Signal: Modulator of Cellular Energy Production and Anabolism

Advanced Science, EarlyView.
Compartmentalized lactate signaling provides a spatial framework for understanding how lactate‐rich states are generated, transported, sensed, and translated into biological outputs. This Review integrates extracellular, cytosolic, mitochondrial‐associated, and nuclear lactate mechanisms to explain how lactate shapes metabolic adaptation, immune ...
Han Wang, Si‐Yuan Yang, Wei Xu
wiley   +1 more source

Unveiling the potential role of the shock index in maternal sepsis: reality or fantasy?

The Journal of Maternal-Fetal & Neonatal Medicine
Objective Maternal sepsis continues to be a maternal health problem associated with 75,000 deaths per year worldwide, representing a greater burden in low- and middle-income countries (LMICs).
María Fernanda Escobar, Isabella Ramos, Ketty Marta Guerra, Natalia Soto Franco, Juan Sebastián Galindo-Sánchez, Laura Libreros-Peña, Evelyn E. Peña-Zárate, Lizbeth A. Guevara-Calderón, Hernán Gómez-Moreno, María Paula Echavarría   +9 more
doaj   +1 more source

BRCA1 Mutation‐Recognizing Tetrahedral Framework Nucleic Acid Nanoplatform Enables Coordinated PARP/WEE1 Inhibition and STING‐Associated Antitumor Immunity in Ovarian Cancer

Advanced Science, EarlyView.
BRCA1 mutation‐responsive FBOA‐tFNA selectively recognizes mutant transcripts and coordinates reduction‐responsive intracellular delivery of olaparib and adavosertib, amplifying DNA damage and weakening G2/M checkpoint protection. These effects are accompanied by STING‐associated immune activation and stronger antitumor immunity, while sequential anti ...
Chenyi Wang, Mengying Yao, Jinhui Xie, Dingjie Wang, Yashi Shi, Xiaodan Mao, Chunhua Lu, Pengming Sun   +7 more
wiley   +1 more source

Guillain-Barré Syndrome after H1N1 Shot in Pregnancy: Maternal and Fetal Care in the Third Trimester—Case Report

Case Reports in Obstetrics and Gynecology, 2012
Guillain-Barré syndrome is a rare neurological disease of progressive installation, usually following a previous acute infectious state, has a rare incidence, especially in pregnancy, and can induce major complications and high mortality risk.
Felipe Favorette Campanharo, Eduardo Felix Martins Santana, Stephanno Gomes Pereira Sarmento, Rosiane Mattar, Sue Yazaki Sun, Antonio Fernandes Moron   +5 more
doaj   +1 more source

Univariable and multivariable analyses of infectious complications.

, 2021
Univariable and multivariable analyses of infectious complications.
Shintaro Mikami (465618), Tatsuya Minami (465617), Masaya Sato (465619), Taijiro Wake (8735415), Mizuki Nishibatake Kinoshita (8735421), Kenichiro Enooku (465621), Koji Uchino (661052), Yoshinari Asaoka (59646), Takuma Nakatsuka (8735424), Ryo Nakagomi (661051), Kazuhiko Koike (135022), Shuichiro Shiina (402272), Ryosuke Tateishi (135017), Hayato Nakagawa (402254)   +13 more
core   +1 more source

Lactate Drives Pathological Browning of White Adipose Tissue to Aggravate Sepsis‐Associated Metabolic Disorders in a GPR81‐Dependent Manner

Advanced Science, EarlyView.
Sepsis‐triggered lactate accumulation induces pathological white adipose tissue browning. Lactate activates adipocyte GPR81 to sequentially upregulate CTRP6‐p38 signalling and UCP1 expression. This cascade exacerbates sepsis‐associated metabolic disorders.
Chunliang Zheng, Xiaohua Li, Shuo Li, Chungen Xing, Chun Cao   +4 more
wiley   +1 more source