Results 51 to 60 of about 185 (86)

Modic Change Bone Marrow Neutrophils Are Activated and Degrade Cartilage Endplates

JOR SPINE, Volume 9, Issue 1, March 2026.
Activated neutrophils accumulate in Modic‐change bone marrow and secrete neutrophil elastase, which drives cartilage endplate destruction and releases glycosaminoglycans. This neutrophil–elastase axis links inflammatory marrow lesions to structural endplate breakdown at the disc–vertebra interface.
Irina Heggli, Tamara Mengis, Jan Devan, Nick Herger, Mazda Farshad, Mohamed Habib, Christopher P. Ames, Oliver Distler, Aaron J. Fields, Stefan Dudli   +9 more
wiley   +1 more source

Minimally invasive percutaneous endoscopic discectomy and drainage for infectious spondylodiscitis

Biomedical Journal, 2013
The primary goals for treating infectious spondylodiscitis are to make an accurate diagnosis, isolate the causative organism, and prescribe effective antibiotic therapy based on the culture data.
Tsai-Sheng Fu, Lih-Hui Chen, Wen-Jer Chen   +2 more
doaj   +1 more source

The Need for Comprehensive Medical Management in Pyogenic Spondylodiscitis: A Review Article

Spine Surgery and Related Research
The incidence of spontaneous or primary spondylodiscitis has been increasing over the years, affecting the aging population with multiple comorbidities.
Rina Therese R. Madelar, Manabu Ito
doaj   +1 more source

Mycotic aortic aneurysm secondary to spondylodiscitis: A case report and review

Radiology Case Reports
Mycotic aneurysms are a rare but potentially life-threatening complication of infections, particularly those involving the spine. Spondylodiscitis, a bacterial or fungal infection of the intervertebral disc, is a known risk factor for the development of ...
Hicham Benramdane, Hamid Ziani, Siham Nasri, Imane Kamaoui, Imane Skiker   +4 more
doaj   +1 more source

Cervical Discitis in a 20‐Year‐Old Female: A Case Report

Clinical Case Reports
Spondylodiscitis, particularly cervical discitis, is a rare infectious condition that can result in severe complications if untreated. This report highlights the rarity of this condition in our female patient's age group and its occurrence in the ...
Saja Karaja, Ahed Assaf, Shafiq Alassaf, Elias Tannous, Hazem Arab, Mulham Alkassem, Amer Al Tawekji   +6 more
doaj   +1 more source

A rare and complex case report of superimposed clostridial spondylodiscitis and epidural abscess associated with spinal lymphoma of the thoracic spine

BMC Infectious Diseases
Background Progressive back pain in elderly individuals may be caused by spine infections, metastatic cancers, or hematologic malignancies. Spine infections, such as spondylodiscitis, often result from hematogenous spread by staphylococci, streptococci ...
Anan Vithitsuwannakun, Witchuda Kamolvit, Piriyaporn Chongtrakool, Sanya Sukpanichnant, Chattree Hantaweepant, Artit Jinawath, Anupop Jitmuang   +6 more
doaj   +1 more source

Magnetic resonance imaging of bacterial and tuberculous spondylodiscitis with associated complications and non-infectious spinal pathology mimicking infections: a pictorial review

BMC Musculoskeletal Disorders, 2017
Magnetic resonance (MR) imaging plays an important role in the evaluation of bacterial and tuberculous spondylodiscitis and associated complications. Owing to its high sensitivity and specificity, it is a powerful diagnostic tool in the early diagnosis ...
Yogesh Kumar, Nishant Gupta, Avneesh Chhabra, Takeshi Fukuda, Neetu Soni, Daichi Hayashi   +5 more
doaj   +1 more source

Brucella spondylodiscitis: Multifocal involvement in thoracic and lumbar areas; a rare case

Journal of Microbiology and Infectious Diseases, 2015
Brucellosis is a zoonosis that can affect many organs or systems. Musculoskeletal system is the most commonly affected site in brucellosis and the frequency of musculoskeletal system involvement varies between 2% and 53%.
Pınar Korkmaz, Zeki Serdar Ataizi, Figen Cağlan Cevik, Nevil Aykın, Hakkı Mustafa Gulduren, Yeşim Alpay, Gulay Şimşek   +6 more
doaj   +1 more source

The role of 18F-FDG PET/CT in early infectious discitis: a case report after a negative MRI

Radiology Case Reports, 2019
We present the case of a 70 years old woman with infectious discitis which was detected using Fluorine fluodeoxiglucose positron emission tomography/computed tomography (18F-FDG PET/CT), after a negative magnetic resonance imaging.
Jorge Juan Fragío-Gil, MD, Roxana González-Mazarío, MD, Marta de la Rubia Navarro, MD, José Andrés Román-Ivorra, PhD   +3 more
doaj   +1 more source

Prolonged and high dosage of tigecycline – successful treatment of spondylodiscitis caused by multidrug-resistant Acinetobacter baumannii: a case report

Journal of Medical Case Reports, 2017
Background The incidence of infectious spondylodiscitis has been increasing over the last few years. This reflects the expanding elderly and immunocompromised populations and the rising implementation of invasive spinal procedures.
Olga Tsachouridou, Adamantini Georgiou, Sideris Nanoudis, Theofilos Chrysanthidis, Georgia Loli, Petros Morfesis, Pantelis Zebekakis, Symeon Metallidis   +7 more
doaj   +1 more source