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The incidence of infective endocarditis (IE) is rising with the increased availability of prosthetic valves and intracardiac devices. In this review, we describe the epidemiologic trends, microbiology, and clinical manifestations of IE. The 2023 Duke-International Society for Cardiovascular Infectious Disease criteria are summarized, as are other ...
Yallowitz AW, Nguyen AD.
europepmc +5 more sources
Challenges in Infective Endocarditis
Infective endocarditis is defined by a focus of infection within the heart and is a feared disease across the field of cardiology. It is frequently acquired in the health care setting, and more than one-half of cases now occur in patients without known heart disease. Despite optimal care, mortality approaches 30% at 1 year.
, Bernard Prendergast, Gilbert Habib
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Association of recurrent fever and anemia with infective endocarditis in a 13-year-old girl with bicuspid aortic valve [PDF]
Introduction. Infective endocarditis is relatively rare in pediatric population, but can result in significant morbidity and mortality. Children with bicuspid aortic valve are at higher risk of developing infective endocarditis as compared to the general
Petrović Vesna +2 more
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Infective endocarditis occurs worldwide, and is defined by infection of a native or prosthetic heart valve, the endocardial surface, or an indwelling cardiac device. The causes and epidemiology of the disease have evolved in recent decades with a doubling of the average patient age and an increased prevalence in patients with indwelling cardiac devices.
Thomas J, Cahill, Bernard D, Prendergast
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Introduction: Infective endocarditis presents a high rate of morbidity and mortality. Population-based studies addressing mortality caused by infective endocarditis in Portugal are scarce.
Catarina de Sousa +2 more
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Novel Tissue Level Effects of the Staphylococcus aureus Enterotoxin Gene Cluster Are Essential for Infective Endocarditis. [PDF]
Superantigens are indispensable virulence factors for Staphylococcus aureus in disease causation. Superantigens stimulate massive immune cell activation, leading to toxic shock syndrome (TSS) and contributing to other illnesses.
Christopher S Stach +6 more
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Infective endocarditis is a severe disease with a high mortality and morbidity, and its clinical heterogeneity is a challenging barrier to rapid diagnosis and treatment.
Yavuzer Koza +2 more
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Diagnosis of infective endocarditis with cardiac CT in an adult
The diagnosis of infective endocarditis is based on modified Duke's criteria, which includes clinical, biological, and echocardiographic findings. However, computed tomography (CT) has not been mentioned as a diagnostic tool in the criteria.
Kotaro Ouchi, MD, PhD +6 more
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BACKGROUND The term “predisposition” is used as an indication of antimicrobial prophylaxis to prevent infective endocarditis and as a criterion for diagnosing infective endocarditis according to the modified Duke criteria.
Annina E. Buechi +4 more
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Infective endocarditis following invasive dental procedures: IDEA case-crossover study
Background: Infective endocarditis is a heart infection with a first-year mortality rate of ≈ 30%. It has long been thought that infective endocarditis is causally associated with bloodstream seeding with oral bacteria in ≈ 40–45% of cases.
Martin H Thornhill +11 more
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