Results 101 to 110 of about 518,510 (312)

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang, Huiying Wang, Zhizheng Zhuo, Ai Guo, Ke Lv, Decai Tian, Chao Chai, Yunyun Duan, Shuang Xia   +8 more
wiley   +1 more source

Exploring the Latent Information in Spatial Transcriptomics Data via Multi‐View Graph Convolutional Network Based on Implicit Contrastive Learning

Advanced Science
Latest developments in spatial transcriptomics enable thoroughly profiling of gene expression while preserving tissue microenvironment. Connecting gene expression with spatial arrangement is key for precise spatial domain identification, enhancing the ...
Sheng Ren, Xingyu Liao, Farong Liu, Jie Li, Xin Gao, Bin Yu   +5 more
doaj   +1 more source

Single-cell and spatial transcriptome assays reveal heterogeneity in gliomas through stress responses and pathway alterations

Frontiers in Immunology
BackgroundGlioma is a highly heterogeneous malignancy of the central nervous system. This heterogeneity is driven by various molecular processes, including neoplastic transformation, cell cycle dysregulation, and angiogenesis.
Zongze He, Zheng Liu, Qi Wang, Xingjian Sima, Wei Zhao, Chunmei He, Wenjie Yang, Han Chen, Bo Gong, Bo Gong, Siyuan Song, Yi Wang, Yi Wang   +12 more
doaj   +1 more source

CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao, Rong Li, Yu‐Xiang Jiao, Kai Ma, Hong‐Qi Yang, Zheng‐Yu Sun, Jie‐Wen Zhang, Shuai Chen   +7 more
wiley   +1 more source

Integrating optogenetic fMRI and spatial transcriptomics to reveal circuit-specific gene signatures in fronto- and hippo-thalamic networks

Nature Communications
Elucidating how microscale molecular architecture shapes macroscale brain network organization requires integrative frameworks that link transcriptional profiles, structural connectivity, and functional dynamics across scales.
Changjiang Zhang, Yijuan Zou, Liangchen Zhuo, Xiya Liu, Suijuan Zhong, Chonghai Yin, Mayuqing Li, Mengdi Wang, Wei Wang, Xin Zhou, Bo Zeng, Changsheng Dong, Le Sun, Zheng Wang, Ang Li, Qian Wu, Xiaoqun Wang   +16 more
doaj   +1 more source

An Intelligent Ship Detection Algorithm Based on Visual Sensor Signal Processing for AIoT-Enabled Maritime Surveillance Automation

Sensors
Oriented object detection constitutes a fundamental yet challenging task in Artificial Intelligence of Things (AIoT)-enabled maritime surveillance, where real-time processing of dense visual streams is imperative.
Liang Zhang, Yueqiu Jiang, Wei Yang, Bo Liu   +3 more
doaj   +1 more source

MAPS OF CONTINUOUS SPATIAL DEPENDENCE [PDF]

Heterogeneity is one of the distinguishing features in spatial econometric models. It is a frequent problem in applied work and can be very damaging for statistical inference.
Jesús MUR, Ana ANGULO, Fernando LOPEZ
core  

Enhancing hyperspectral image unmixing with spatial correlations [PDF]

, 2010
This paper describes a new algorithm for hyperspectral image unmixing. Most unmixing algorithms proposed in the literature do not take into account the possible spatial correlations between the pixels.
Jean-Yves Tourneret, Eches, Olivier, Olivier Eches, Nicolas Dobigeon, Dobigeon, Nicolas, Tourneret, Jean-Yves   +5 more
core   +1 more source

Effectiveness of rTMS on Working Memory and Inhibitory Impairments in Patients With Post‐Stroke Executive Deficits

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Considerable efforts have been dedicated to developing effective treatments for post‐stroke executive impairment (PSEI), among which repetitive transcranial magnetic stimulation (rTMS) has shown great potential. This study aimed to investigate the therapeutic effects of high‐frequency rTMS on working memory (WM) and response ...
Mengting Lao, Rongwei Du, Zhujun Wang, Yang Gao, Meiling Cheng, Xianglong Wang, Wen Wu   +6 more
wiley   +1 more source

The Spatial Analysis of Time Series [PDF]

In this paper, we propose a method of analyzing time series, called the spatial analysis. The analysis consists mainly of the statistical inference on the distribution given by the expected local time, which we define to be the spatial distribution, of a
Park, Joon Y.
core