Results 81 to 90 of about 6,007 (228)

Glaucoma animal models in rabbits: State of the art and perspectives—A review

open access: yesAnimal Models and Experimental Medicine, Volume 8, Issue 3, Page 429-440, March 2025.
Glaucoma, a visual thief, is characterized by elevated intraocular pressure (IOP) and loss of retinal ganglion cells (RGCs). Selecting suitable animals for preclinical models is of great significance in research on the prevention, early screening, and effective treatments of glaucoma.
Rong Hu   +4 more
wiley   +1 more source

Auditory opportunity and visual constraint enabled the evolution of echolocation in bats [PDF]

open access: yes, 2018
Substantial evidence now supports the hypothesis that the common ancestor of bats was nocturnal and capable of both powered flight and laryngeal echolocation.
Thiagavel, Jeneni   +5 more
core   +3 more sources

A Viral Labelling Study of Spinal Trigeminal Nucleus Caudalis Projection Neurons Targeting the Parabrachial Nucleus

open access: yesJournal of Neurochemistry, Volume 169, Issue 3, March 2025.
Using adeno‐associated viral vectors (AAVs) to label projection neurons (PN) that link nervous system regions is a powerful tool in neuroscience for studying circuitry and function. However, AAVs exhibit tropism, which can produce variable expression depending on the viral serotype and the CNS region targeted.
Sophie Maric   +4 more
wiley   +1 more source

Transcortical photothrombotic pyramidotomy model with persistent motor deficits.

open access: yesPLoS ONE, 2018
Traditional pyramidotomy models have a high mortality rate from breathing difficulties and show early recovery from the induced motor deficits. This study establishes a novel pyramidotomy technique in Sprague Dawley rats that generates persistent motor ...
Hanlim Song   +8 more
doaj   +1 more source

Sex-Specific Brain Deficits in Auditory Processing in an Animal Model of Cocaine-Related Schizophrenic Disorders

open access: yesBrain Sciences, 2013
Cocaine is a psychostimulant in the pharmacological class of drugs called Local Anesthetics. Interestingly, cocaine is the only drug in this class that has a chemical formula comprised of a tropane ring and is, moreover, addictive.
Patricia A. Broderick, Taylor Rosenbaum
doaj   +1 more source

Нервова система. Органи чуття [PDF]

open access: yes, 2010
Посібник побудовано з урахуванням Міжнародної анатомічної номенклатури(San Paulo, 1997) та у відповідності до викладання дисципліни в умовах кредитно – модульної системи.
Bolotna, Iryna Vasylivna   +28 more
core  

GABAergic neurons regulate lateral ventricular development via transcription factor Pax5 [PDF]

open access: yes, 2013
Postmortem studies have revealed a downregulation of the transcription factor Pax5 in GABAergic neurons in bipolar disorder, a neurodevelopmental disorder, raising the question whether Pax5 in GABAergic neurons has a role in normal brain development.
Asada   +34 more
core   +2 more sources

Locus Coeruleus Degeneration in Essential Tremor With Mild Cognitive Impairment: A Neuromelanin MRI Study

open access: yesCNS Neuroscience &Therapeutics, Volume 31, Issue 1, January 2025.
Using neuromelanin‐sensitive‐MRI (NM‐MRI) analysis, we found the integrity of locus coeruleus (LC) was decreased in ET patients and be more pronounced in ET‐MCI patients. The decreased integrity of LC was correlated with the severity of cognitive functions, suggesting some pathological changes of LC contribute to the cognitive impairment in ET ...
Yuelin Fang   +13 more
wiley   +1 more source

Editorial: The Jilted Brain: Neglected Structures and Functions

open access: yesFrontiers in Systems Neuroscience, 2021
Regina A. Mangieri   +2 more
doaj   +1 more source

Early detection of neurodegeneration in brain ischemia by manganese-enhanced MRI [PDF]

open access: yes, 2008
This study aims to employ in vivo manganese-enhanced MRI (MEMRI) to detect neurodegenerative changes in two models of brain ischemia, photothrombotic cortical injury (PCI) and transient middle cerebral artery occlusion (MCAO) in rodents.
Cai, KX   +10 more
core   +1 more source

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