Results 61 to 70 of about 953,209 (297)

Unraveling genetic causality between metformin and myocardial infarction on the basis of Mendelian randomization

Frontiers in Endocrinology
BackgroundIn recent years, several studies have explored the effect of metformin on myocardial infarction (MI), but whether metformin has an improvement effect in patients with MI is controversial.
Yongru Zhuang, Yongru Zhuang, Xiaojun Pan, Ya Chen, Jinfang Song, Jinfang Song   +5 more
doaj   +1 more source

Mechanisms and predictors of ischemic mitral regurgitation at rest and on exertion in patients at early stage of myocardial infarction

Российский кардиологический журнал, 2020
Aim. Determination of the mechanisms and predictors of ischemic mitral regurgitation (IMR) at rest and on exertion in patients at early stage of myocardial infarction (MI).Material and methods.
K. G. Adamyan, A. L. Chilingaryan, N. G. Mkrtchyan, L. G. Tunyan   +3 more
doaj   +1 more source

La investigación nacional en informática [PDF]

, 1976
Todo sector tiene sus peculiaridades. El de la informática, cuyos gastos totales en España para este año de 1976 fueron estimados modestamente en cifras del orden de 40.000 millones de pesetas, de las que alrededor de un 40 al 45% irán a compra o ...
Sáez Vacas, Fernando
core   +1 more source

Rationale and design of the Clinical Evaluation of Magnetic Resonance Imaging in Coronary heart disease 2 trial (CE-MARC 2): a prospective, multicenter, randomized trial of diagnostic strategies in suspected coronary heart disease [PDF]

, 2015
Background: A number of investigative strategies exist for the diagnosis of coronary heart disease (CHD). Despite the widespread availability of noninvasive imaging, invasive angiography is commonly used early in the diagnostic pathway.
Berry, Colin, Bijsterveld, Petra, Brown, Julia, Everett, Colin C., Greenwood, John P., McCann, Gerry P., Plein, Sven, Ripley, David P., Sculpher, Mark, Walker, Simon   +9 more
core   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Comparing angiography features of inferior versus anterior myocardial infarction regarding severity and extension in a cohort of Iranian patients

Journal of Research in Medical Sciences, 2011
Background: The location of acute myocardial infarction (MI) is an important prognostic factor for risk stratification of patients with first ST-segment elevation MI (STEMI).
Elham Hakki Kazazi, Mehrdad Sheikhvatan, Mehran Mahmoodian, Mahmood Sheikh Fathollahi, Hakimeh Sadeghian   +4 more
doaj  

Detection of Inferior Myocardial Infarction using Shallow Convolutional Neural Networks

, 2018
Myocardial Infarction is one of the leading causes of death worldwide. This paper presents a Convolutional Neural Network (CNN) architecture which takes raw Electrocardiography (ECG) signal from lead II, III and AVF and differentiates between inferior ...
Reasat, Tahsin, Shahnaz, Celia
core   +1 more source

Brain MR Spectroscopy Changes Precede Frontotemporal Lobar Degeneration Phenoconversion in Mapt Mutation Carriers. [PDF]

, 2019
Background and purposeThe objective of this study was to longitudinally investigate the trajectory of change in 1 H MRS measurements in asymptomatic MAPT mutation carriers who became symptomatic during follow-up, and to determine the time at which the ...
Boeve, Bradley F, Boxer, Adam L, Brushaber, Danielle, Chen, Qin, Dheel, Christina, Fields, Julie, Forsberg, Leah, Gavrilova, Ralitza, Gearhart, Debra, Graff-Radford, Jonathan, Graff-Radford, Neill, Gunter, Jeffrey L, Haley, Dana, Jones, David, Kantarci, Kejal, Knopman, David, Kraft, Ruth, Lapid, Maria, Lesnick, Timothy, Rademakers, Rosa, Rosen, Howie, Tosakulwong, Nirubol, Wszolek, Zbigniew K   +22 more
core   +3 more sources

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

Mendelian randomization study of the effect of coronary artery calcification on atherosclerotic cardiovascular diseases

Scientific Reports, 2022
Calcium calcification in the wall of arteries (CAC) leads to a higher risk of atherosclerosis related outcomes, especially myocardial infarction (MI). Nevertheless, the causal role of CAC on other related outcomes is unclear.
Wichanon Sae-jie, Tarinee Tangcharoen, Prin Vathesatogkit, Wichai Aekplakorn, Pimphen Charoen   +4 more
doaj   +1 more source