Neuropathology, Volume 45, Issue 6, December 2025.ABSTRACT Herein, we report two autopsy cases of familial ALS with a p. L127S (L126S) SOD1 variant. Case 1 involved a 62‐year‐old woman who presented with lower‐extremity muscle weakness with lower motor neuron signs. The patient developed bulbar palsy and died of respiratory failure 9 years after onset.
Kimiko Inoue +6 more
wiley +1 more source
A retrograde double-labeling technique for light microscopy A combination of axonal transport of cholera toxin B-subunit and a gold-lectin conjugate [PDF]
, 1995 A light microscopical, non-fluorescent, retrograde double-labeling technique is described. Cholera toxin B-subunit (CTb) and a conjugate of wheatgerm agglutinin and bovine serum albumin coupled to 10 nm gold particles (gold-lectin) are both excellent ...
Burg, J. (Hans) van der +3 more
core +1 more source
Atypical Frontotemporal Dementia Associated With SQSTM1 Gene Mutation: A Clinicopathological Case
Neuropathology, Volume 45, Issue 6, December 2025.ABSTRACT A 78‐year‐old man presented with a six‐year history of progressive memory decline, initially manifesting as recent memory impairment and mild anomia, which gradually evolved into motor clumsiness, gait disturbances, language difficulties, behavioral changes, and late‐onset parkinsonism. He had been diagnosed with Paget disease of bone (PDB) at
Christian Espinoza‐Vinces +8 more
wiley +1 more source
Cross-Correlation in the Auditory Coincidence Detectors of Owls [PDF]
, 2008 Interaural time difference (ITD) plays a central role in many auditory functions, most importantly in sound localization. The classic model for how ITD is computed was put forth by Jeffress (1948). One of the predictions of the Jeffress model is that the
Christianson, G. Björn +2 more
core +1 more source
A Computer Modeling Approach to Understanding the Inferior Olive and Its Relationships to the Cerebellar Cortex in Rats [PDF]
, 1990 This paper presents the results of a simulation of the spatial relationship between the inferior olivary nucleus and folium crus IIA of the lateral hemisphere of the rat cerebellum.
Bower, James M., Lee, Maurice
core
A receptor-based analysis of local ecosystems in the human brain. [PDF]
, 2017 BackgroundAs a complex system, the brain is a self-organizing entity that depends on local interactions among cells. Its regions (anatomically defined nuclei and areas) can be conceptualized as cellular ecosystems, but the similarity of their functional ...
Janušonis, Skirmantas
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Frontiers in Neurology, 2017 Wernekink commissure syndrome secondary to caudal paramedian midbrain infarction (CPMI) is a rare midbrain syndrome involving the decussation of the superior cerebellar peduncle in the caudal paramedian midbrain tegmentum. The central characteristics are
Chenguang Zhou +8 more
doaj +1 more source
Zonal organization of the climbing fiber projection to the flocculus and nodulus of the rabbit: A combined axonal tracing and acetylcholinesterase histochemical study [PDF]
, 1995 The localization and termination of olivocerebellar fibers in the flocculus and nodulus of the rabbit were studied with anterograde axonal transport methods [wheatgerm agglutinin-horseradish peroxidase (WGA-HRP) and tritiated leucine] and correlated with
Gerrits, N.M. (N.) +4 more
core +2 more sources
Caveats in transneuronal tracing with unmodified rabies virus: An evaluation of aberrant results using a nearly perfect tracing technique [PDF]
, 2016 Apart from the genetically engineered, modified, strains of rabies virus (RABV), unmodified ‘fixed’ virus strains of RABV, such as the ‘French’ subtype of CVS11, are used to examine synaptically connected networks in the brain.
Coulon, P. (Patrice) +2 more
core +5 more sources
Connections of the Superior Paraolivary Nucleus of the Rat: II. Reciprocal Connections with the Tectal Longitudinal Column [PDF]
, 2011 The superior paraolivary nucleus (SPON), a prominent GABAergic center of the mammalian auditory brainstem, projects to the ipsilateral inferior colliculus (IC) and sends axons through the commissure of the IC (CoIC).
Antonio Viñuela +3 more
core +2 more sources