Another Rare Cause of Hypertrophic Olivary Degeneration Following Cavernous Malformation Hemorrhage: A Case Report [PDF]
DiagnosticsIntroduction: Hypertrophic olivary degeneration (HOD) is a rare form of trans-synaptic degeneration involving the Guillain–Mollaret triangle, characterized by enlargement of the inferior olivary nucleus—unlike the atrophy typical of most ...
Sigita Skrastiņa +5 more
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Hypertrophic olivary degeneration: a 7 Tesla advanced imaging case report [PDF]
Frontiers in NeuroscienceBackground and objectivesA 50-year-old patient developed ataxia, nystagmus, and palatal tremor. Conventional magnetic resonance imaging (MRI) revealed inferior olivary nuclei enlargement and hyperintensity in T2-weighted images, indicating hypertrophic ...
Tommaso Calzoni +9 more
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The inferior olivary nucleus: a postmortem study of essential tremor cases versus controls. [PDF]
Mov Disord, 2013 ABSTRACTThe pathogenesis of essential tremor is poorly understood. Historically, it has been hypothesized that the inferior olivary nucleus plays an important role in the generation of tremor in essential tremor, yet a detailed, controlled, anatomic‐pathological study of that brain region has yet to be conducted.
Louis ED +4 more
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Unusual co-occurrence of hypertrophic inferior olivary degeneration with infratentorial cavernomatosis and orbital cavernous hemangioma [PDF]
Radiology Case ReportsHypertrophic olivary degeneration (HOD) is a rare condition resulting from a lesion in the Guillain-Mollaret triangle (GMT), causing transsynaptic degeneration and hypertrophy of the inferior olivary nucleus (ION).
Jihane EL Houssni +6 more
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Clinical characteristics of hypertrophic olivary degeneration following brainstem or cerebellar hemorrhage [PDF]
Scientific ReportsPatients who have experienced bleeding in the posterior circulation of the brain often develop Hypertrophic Olivary Degeneration (HOD). This condition can lead to new neurological problems several months after the initial hemorrhage, potentially ...
Lin Lin, Xiaofeng Ye, Jianming Zheng
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Bilateral Hypertrophic Olivary Degeneration Following Unilateral Mesencephalic Hemorrhage. [PDF]
Clin Case RepABSTRACT After a unilateral midbrain hemorrhage, clinicians should recognize that bilateral hypertrophic olivary degeneration may occur, presenting as palatal myoclonus, dysarthria, or tinnitus. This highlights the necessity for timely diagnosis and effective symptom management.
Razmeh S, Dashti AM, Habibi AH.
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AAV-PHP.eB Peripheral Delivery and Central Expression in Cre Mice. [PDF]
J Comp NeurolRetro‐orbital injection of AAV‐PHP.eB‐FLEX‐tdTomato into four different strains of Cre mice produced various and distinct patterns of transduction efficiency and tropism across brain regions and cell types. We found many target neurons expressing tdTomato in most but not all strains, along with a low level of nonspecific (Cre‐independent) expression ...
Zhu H, Geerling JC.
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Identification of sensory relay nuclei in brainstem that projecting to the dorsal raphe nucleus
Di-san junyi daxue xuebao, 2021 Objective To explore the distribution and contact pattern of sensory relay nuclei in the brainstem that projecting to the dorsal raphe nucleus (DRN) by using neural circuit tracing technique, so as to investigate the morphological basis of sensory ...
ZHANG Cai +4 more
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Frontiers in Systems Neuroscience, 2023 Recent studies have shown that the cerebellum and the basal ganglia are interconnected at subcortical levels. However, a subcortical basal ganglia connection to the inferior olive (IO), being the source of the olivocerebellar climbing fiber system, is ...
Tom J. H. Ruigrok +4 more
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A Rare Case of Familial Progressive Ataxia with Palatal Tremors [PDF]
Journal of Clinical and Diagnostic Research, 2022 A 25-year-old female patient presented with insidious onset progressive difficulties of gait and balance. Onset of these symptoms first appeared nine years prior and evolved to include changes in speech, increased occurrence of falls and spastic ...
Abhilash Mishra +4 more
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