Results 71 to 80 of about 10,293 (180)

Agonist‐specific conformational dynamics at the β2‐adrenoceptor dictate allosteric modulation of Gαs signalling and bronchodilation

British Journal of Pharmacology, Volume 183, Issue 17, Page 5315-5335, September 2026.
Abstract Background and Purpose β2‐adrenoceptor (β2AR) agonists are the cornerstone of asthma therapy and promote bronchodilation through Gαs signalling in airway smooth muscle (ASM), but their efficacy is limited by β‐arrestin‐mediated β2AR desensitization.
Sushrut D. Shah, Joshua Richard, Suvankar Ghosh, Jillian Jerwick, Joice T. Gavali, Raymond B. Penn, Alexander D. MacKerell Jr, Deepak A. Deshpande   +7 more
wiley   +1 more source

Successful retrieval of a vena cava filter in a patient with duodenal perforation by open surgery: a case report and literature review

Journal of Cardiothoracic Surgery
Background Vena cava filter placement represents a safe and effective intervention to prevent the potential occurrence of pulmonary embolism caused by the dislodgement of deep vein thrombosis.
Renzhi Chen, Chong Liu, Haizhou Pan, Bing Han, Haidi Hu   +4 more
doaj   +1 more source

Optimizing inferior vena cava filter design: A computational fluid dynamics study on strut configuration for enhanced hemodynamic performance and thrombosis reduction

Heliyon
Background and objective: Inferior vena cava filters have been shown to be effective in preventing deep vein thrombosis and its secondary complication, pulmonary embolism, thereby reducing the high mortality rate. Although inferior vena cava filters have
Byeong-Jun Kim, Chiseung Lee
doaj   +1 more source

Inferior Vena Cava Filter Placement during Pregnancy: An Adjuvant Option When Medical Therapy Fails

Case Reports in Obstetrics and Gynecology, 2013
The authors present a case of a 27-year-old multiparous woman, with multiple thrombophilia, whose pregnancy was complicated with deep venous thrombosis requiring placement of a vena cava filter.
Sara Valadares, Fátima Serrano, Rita Torres, Augusta Borges   +3 more
doaj   +1 more source

Oral PHGG ameliorates atopic dermatitis‐like dermatitis with concurrent modulation of colonic IgA and cecal microbiota: implications for the gut–skin axis

Journal of the Science of Food and Agriculture, Volume 106, Issue 11, Page 6380-6394, 30 August 2026.
Abstract BACKGROUND Atopic dermatitis (AD) is increasingly recognized as a systemic inflammatory disorder linked to intestinal immune and microbiome dysregulation. However, whether dietary galactomannan fibers can mitigate AD through coordinated modulation of the gut–skin axis remains unexplored.
Derrick Kakooza, Hyeonjun Yu, Jonghyun Jeong, Jung Cheul Shin, Woo Jung Kim, Sung‐Kwon Moon, Hoon Kim   +6 more
wiley   +1 more source

Dose‐Dependent Anti‐Obesity and Protective Effects of Chia (Salvia hispanica L.) Seed Oil Against Hematological and Hepatorenal Dysfunction in High‐Fat Diet–Fed Mice

Food Science &Nutrition, Volume 14, Issue 8, August 2026.
Chia seed oil ameliorates obesity, dyslipidemia, and hepatorenal dysfunction in high‐fat diet–fed mice. ABSTRACT Chia seeds (Salvia hispanica L.) are recognized as a functional food with a nutrient‐dense profile and health‐promoting properties. In the present study, hexane‐extracted chia seed oil was investigated for anti‐obesity, hematoprotective, and
Sabbya Sachi, Mst. Prianka Jahan, Sree Alok Kumar, Mahmudul Hasan Sikder, Md. Zahorul Islam   +4 more
wiley   +1 more source

Parasympathetic Tone Selectively Modulates Electrogram Fragmentation and Spectral Properties in Right Atrial Ganglionated Plexi

Journal of Arrhythmia, Volume 42, Issue 4, August 2026.
Electrogram fragmentation and spectral EGMs features in GPs area are selectively modulated by parasympathetic tone, as demonstrated by high‐density right atrial mapping before and after vagal blockade. EGMs, bipolar atrial electrograms; GPs, ganglionated plexi; RA, right atrium.
Andrea Giomi, Andrea Bernardini, Alessandro Paoletti Perini, Margherita Padeletti, Cristiano Salvatore Zaccaria, Federica Michelotti, Umberto Signorini, Rossella Marcucci, Massimo Milli   +8 more
wiley   +1 more source

Deresuscitation Informed by Ultrasound in Patients With Septic Shock Trial

Journal of Ultrasound in Medicine, Volume 45, Issue 8, Page 1685-1693, August 2026.
Objectives The venous excess ultrasound (VExUS) can be used at the point‐of‐care to identify venous overload and end‐organ congestion in an effort to individually tailor resuscitation and deresuscitation in patients with septic shock. Methods We conducted a pilot randomized controlled feasibility trial of VExUS‐guided fluid management in adult patients
Brendan Innes, Christopher Allison, Nicholas Seidler, Burton Shen, Andrew Fried, Gary Phillips, Andrew Levinson, Adeel Abbasi   +7 more
wiley   +1 more source

Aspiration Thrombectomy in a Patient with Suprarenal Inferior Vena Cava Thrombosis

Case Reports in Cardiology, 2015
DVT has rarely been observed in the inferior vena cava (IVC). Pulmonary embolism (PE), which can be life-threatening, often occurred in patients with IVC thrombosis.
Hideyuki Kishima, Masashi Fukunaga, Kunihiko Nishian, Ten Saita, Tetsuo Horimatsu, Masataka Sugahara, Takanao Mine, Tohru Masuyama   +7 more
doaj   +1 more source

Tine after tine: a varied approach to the removal of a long-standing IVC filter

Radiology Case Reports, 2017
Inferior vena cava filters are important tools used to help prevent life-threatening pulmonary embolisms in hospitalized patients with contraindications to pharmacological prophylactic anticoagulation.
Andrew Delozier, Melhem Ghaleb, MD, Alonso Andrade, MD   +2 more
doaj   +1 more source