Results 1 to 10 of about 3,159,980 (263)

Letrozole for Female Infertility [PDF]

Frontiers in Endocrinology, 2021
Letrozole, an aromatase inhibitor that blocks estrogen synthesis by inhibiting the final step of the estrogen biosynthetic pathway, has been used in the applications of a wide range of infertility settings. It has been more than 20 years since the initial clinical trial of letrozole for ovulation induction.
Guimin Hao, Aimin Yang, Yi-Fei Sun, Na Cui   +3 more
openaire   +5 more sources

Genome-wide analyses identify 25 infertility loci and relationships with reproductive traits across the allele frequency spectrum. [PDF]

Nat Genet
Genome-wide association studies (GWASs) may help inform the etiology of infertility. Here, we perform GWAS meta-analyses across seven cohorts in up to 42,629 cases and 740,619 controls and identify 25 genetic risk loci for male and female infertility. We
Venkatesh SS, Wittemans LBL, Palmer DS, Baya NA, Ferreira T, Hill B, Lassen FH, Parker MJ, Reibe S, Elhakeem A, Banasik K, Bruun MT, Erikstrup C, Aagard Jensen B, Juul A, Mikkelsen C, Nielsen HS, Ostrowski SR, Pedersen OB, Rohde PD, Sørensen E, Ullum H, Westergaard D, Haraldsson A, Holm H, Jonsdottir I, Olafsson I, Steingrimsdottir T, Steinthorsdottir V, Thorleifsson G, Figueredo J, Karjalainen MK, Pasanen A, Jacobs BM, Kalantzis G, Hubers N, Genes & Health Research Team, Estonian Biobank Research Team, Estonian Health Informatics Research Team, DBDS Genomic Consortium, FinnGen, Lippincott M, Fraser A, Lawlor DA, Timpson NJ, Nyegaard M, Stefansson K, Magi R, Laivuori H, van Heel DA, Boomsma DI, Balasubramanian R, Seminara SB, Chan YM, Laisk T, Lindgren CM.   +55 more
europepmc   +3 more sources

Spontaneous pregnancies and determinant factors in infertility: A cross-sectional study [PDF]

, 2020
Background: The phenomenon of infertility may be derived from different factors - either in males or females or both genders, including few unexplained factors. It is generally managed by medical and surgical treatments.
Amininezhad, Fatemeh Sadat, Nikbakht, Roshan, Saadati, Nasrin, Sattari, Alireza   +3 more
core   +3 more sources

The Sexual Impact of Infertility Among Women Seeking Fertility Care. [PDF]

, 2016
IntroductionInfertility affects approximately 6.7 million women in the United States. Couples with infertility have significantly more anxiety, depression, and stress.
Infertility Outcomes Program Project Group, Katz, Patricia P, Rowen, Tami S, Smith, James F, Winkelman, William D   +4 more
core   +2 more sources

Methylation Status of Imprinted Genes and Repetitive Elements in Sperm DNA from Infertile Males [PDF]

, 2011
Stochastic, environmentally and/or genetically induced disturbances in the genome-wide epigenetic reprogramming processes during male germ-cell development may contribute to male infertility.
El Hajj, N., Gromoll, J., Haaf, T., Hahn, T., Schneider, E., Schorsch, M., Tresch, A., Zechner, Ulrich   +7 more
core   +1 more source

Application of ultrasonography in female infertility: a comprehensive review [PDF]

, 2017
The quest for detailed evaluation of the uterus, fallopian tubes, and ovaries that is radiation free, inexpensive, readily available, non-invasive, relatively less time consuming and easily repeatable in female infertility has resulted in further studies.
Agwuna, Kennedy K., Ezenyeaku, Cyril C., Ikeako, Lawrence C., Okeke, Tochukwu C.   +3 more
core   +2 more sources

Factors associated with failed treatment : an analysis of 121,744 women embarking on their first IVF cycles [PDF]

, 2013
Peer reviewedPublisher ...
A Strandell, A Templeton, Abha Maheshwari, AM Stolwijk, AP Ferraretti, B Maugey-Laulom, CC Hunault, CH Syrop, DA Lawlor, E Hauzman, G Zou, Guy Brock, Jill Mollison, JK Min, K Ferlitsch, L Sabatini, LA McNutt, LD Ottosen, LF Bancsi, LL van Loendersloot, LL Van Loendersloot, MH van der Gaast, N Johnson, R Hart, S Greenland, Siladitya Bhattacharya, SK Sunkara, SM Ebbesen, SM Nelson, V Sharma, YA Wang   +30 more
core   +3 more sources

From laboratory bench to benchmark: technology transfer in laboratory medicine [PDF]

, 2020
Background: Life Sciences research, enhancing the occurrence of innovation, is able to impact clinical decision-making, both at diagnosis and therapy. Indeed, starting from the knowledge of specific needs and of technical-scientific demands, researchers ...
Cariati, Federica, D’Argenio, Valeria, Izquierdo, Raul, Tomaiuolo, Rossella   +3 more
core   +1 more source

A hidden cause of infertility in hypothyroid patients [PDF]

, 2020
Methylene tetrahydrofolate reductase (MTHFR) gene mutations could be the cause of infertility in hypothyroid patients. Hence, it is worthy to screen for MTHFR gene mutations in infertile hypothyroid females and their partners if infertility persists ...
Ahmed, Soha Magdy, Allam, Magdy Mohamed, Barakat, Sherine Samir, El-Zawawy, Hanaa Tarek, Saleh, Rasha Noureldin M.   +4 more
core   +1 more source

Women with infertility complying with and resisting polygyny : an explorative qualitative study in urban Gambia [PDF]

, 2019
Background. In many low-and middle-income countries women with infertility are often in polygynous marriages. From a human and women's rights perspective, the practice of polygyny is commonly understood as harmful.
Coene, Gily, Dierickx, Susan, Jarju, Bintou, Longman, Chia   +3 more
core   +1 more source