Results 121 to 130 of about 1,837,464 (375)

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Influência da aplicação de águas residuárias de suinocultura na capacidade de infiltração de um solo Podzólico Vermelho-Amarelo Influence of swine wastewater application on the infiltration capacity of a Yellow-Red Podzol

open access: yesRevista Brasileira de Engenharia Agrícola e Ambiental, 2000
Este trabalho foi conduzido na Área Experimental de Hidráulica, Irrigação e Drenagem do Departamento de Engenharia Agrícola da Universidade Federal de Viçosa, em Viçosa, MG, com o objetivo de se avaliar a influência de aplicações sucessivas de águas ...
Rubens Alves Oliveira   +4 more
doaj   +1 more source

Intraocular Infiltration [PDF]

open access: yesThe American Journal of Tropical Medicine and Hygiene, 2020
Kamoi, Koju, Ohno-Matsui, Kyoko
openaire   +2 more sources

Targeting autophagy inhibits melanoma growth by enhancing NK cells infiltration in a CCL5-dependent manner

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2017
Significance The failure in achieving a durable clinical immune response against cancer cells depends on the ability of cancer cells to establish a microenvironment that prevent cytotoxic immune cells to infiltrate tumors and kill cancer cells. Therefore,
T. Mgrditchian   +15 more
semanticscholar   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

Effect of temporal averaging of meteorological data on predictions of groundwater recharge

open access: yesJournal of Hydrology and Hydromechanics, 2018
Accurate estimates of infiltration and groundwater recharge are critical for many hydrologic, agricultural and environmental applications. Anticipated climate change in many regions of the world, especially in tropical areas, is expected to increase the ...
Batalha Marcia S.   +3 more
doaj   +1 more source

Infiltration

open access: yesGrounded Theory Review: An International Journal, 2023
This is a grounded theory of the basic social process of infiltration. Novice researchers, infants, foreigners and new recruits all face conceptually similar problems of being able to successfully infiltrate into an array of alien situations. The grounded theory emerged from data from the context of a novice researcher gaining and sustaining access for
Wendy Guthrie, Andy Lowe
openaire   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

A Comparative Analysis of WinSRFR and SIRMOD Software for Simulating Surge and Alternate Furrow Irrigation Performance in Maize Fields [PDF]

open access: yesعلوم و مهندسی آبیاری
In order to compare of WinSRFR and SIRMOD software in simulating furrow irrigation performance, a field experiment was carried out in the Jayedar Plain.
Akbar Mehri   +3 more
doaj   +1 more source

On the simulation of infiltration- and saturation-excess runoff using radar-based rainfall estimates: Effects of algorithm uncertainty and pixel aggregation [PDF]

open access: yes, 1998
The effects of uncertainty in radar-estimated precipitation input on simulated runoff generation from a medium-sized (100-km2) basin in northern Texas are investigated.
Gupta, HV, Sorooshian, S, Winchell, M
core   +1 more source

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