Results 131 to 140 of about 1,837,464 (375)
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
Molecular Oncology, EarlyView.p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
Heparanase promotes tumor infiltration and antitumor activity of CAR-redirected T-lymphocytes
Nature Medicine, 2015 Adoptive transfer of chimeric antigen receptor (CAR)-redirected T lymphocytes (CAR-T cells) has had less striking therapeutic effects in solid tumors than in lymphoid malignancies.
Ignazio Caruana +8 more
semanticscholar +1 more source
Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity
Molecular Oncology, EarlyView.Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek +2 more
wiley +1 more source
, 2013 In this study we show how to use GPR data acquired along the infiltration of water inside a single ring infiltrometer to inverse the saturated hydraulic conductivity. We used Hydrus-1D to simulate the water infiltration.
Coquet, Yves +2 more
core +1 more source
Development and evaluation of hybrid aluminium matrix syntactic foams [PDF]
, 2013 A special class of metallic foams, the so called metal matrix syntactic foams was produced by pressure infiltration technique. Metal matrix syntactic foams consist of a light-weight metal matrix and a set of hollow spheres.
Májlinger, Kornél +1 more
core
Comparison of the Efficacy of Dexamethasone and Methylprednisolone in Infiltration Injection for Postendodontic Pain in Patients with Necrotic Pulp: A Randomized Controlled Clinical Trial [PDF]
, 2022 Sheyda Yeganegi +3 more
openalex +1 more source
Development and analysis of the Soil Water Infiltration Global database
Earth System Science Data, 2018 . In this paper, we present and analyze a novel global database of soil infiltration measurements, the Soil Water Infiltration Global (SWIG) database. In total, 5023 infiltration curves were collected across all continents in the SWIG database.
M. Rahmati +128 more
semanticscholar +1 more source
Protein O‐glycosylation in the Bacteroidota phylum
FEBS Open Bio, EarlyView.Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns +2 more
wiley +1 more source
Porous concrete mixtures for pervious urban pavements
Materiales de Construccion, 2007 The present study aimed to analyze the hydraulic and mechanical behaviour of a series of roller-compacted, laboratory porous concrete mixtures. The mix design variables examined were the actual void ratio in the hardened concrete and the water/cement ...
H. de Solminihac +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee +3 more
wiley +1 more source