Results 61 to 70 of about 15,291,451 (253)
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
A Physically Based Two-Dimensional Infiltration Model for Furrow Irrigation [PDF]
, 2002 A two-dimensional physically based infiltration model was developed for furrowirrigation. Infiltration was simulated using the Green-Ampt infiltration method.
Skonard, Christopher J. +1 more
core
Molecular Oncology, EarlyView.Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso +5 more
wiley +1 more source
Modeling of infiltration from an artificial recharge basin with a decreasing ponded depth
, 1991 The first important physical process in basin recharge is the infiltration of water from the basin's bed to the water table below. The Green and Ampt approach was applied to model infiltration from an artificial recharge basin with a decreasing ponded ...
AI-Muttair, Fouad F. +1 more
core
CFD-DEM simulation of slurry particle infiltration in granular soils [PDF]
Over recent decades, the slurry pressure balance (SPB) method has gained popularity due to its safety, efficiency, and environmental advantages, especially in undersea and river-crossing tunnels with high groundwater pressures. By employing a pressurised
Liu, Jiayuan
core +1 more source
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
Instrumented soil column model for rainfall infiltration study
, 2008 Infiltration and changes on pore-water pressure in soil must be taken into account in most slope stability and seepage problems. Laboratory experiments were performed to examine one-dimensional rainfall infiltration behavior of unsaturated soil.
Gofar, Nurly +2 more
core
Simulating infiltration into stony soils with a dual-porosity model
, 2008 Soils containing rock fragments are widely distributed in the world. However, literature on the dynamic simulation of water movement in stony soils is scarce.
Shao, MG +2 more
core +1 more source
Molecular Oncology, EarlyView.LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David +12 more
wiley +1 more source
Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy
Molecular Oncology, EarlyView.LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir +9 more
wiley +1 more source