Results 71 to 80 of about 7,613,404 (283)
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
Evaluation of infiltration models in clay loam and laterite soils under field conditions
Environment Conservation JournalThe purpose of the investigation is to calculate soil infiltration rates with the help of infiltration models. The infiltration model helps to design and evaluate surface irrigation systems.
Shubham Kindo +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso +5 more
wiley +1 more source
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
Stability analysis of an earth embankment subjected to rainfall infiltration - Analisi di stabilità di un rilevato in terra soggetto ad infiltrazione di acque di pioggia [PDF]
, 2013 In the present thesis, an attempt was made to study, with a numerical software, how the rainfall infiltration influences the stresses and the behavior of a soil embankment according to different hydraulic permeability values and rainfall intensities.
Bertoldo, Daniele
core
Molecular Oncology, EarlyView.LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David +12 more
wiley +1 more source
Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy
Molecular Oncology, EarlyView.LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir +9 more
wiley +1 more source
Improved Interflow and Infiltration Algorithms for Distributed Hydrological Models [PDF]
, 2010 The shallow subsurface controls the partitioning of available energy between sensible and latent heat of the land surface, and the partitioning of available water among evaporation, infiltration, and runoff.
Liu, Guoxiang
core
Review of conceptual and empirical approaches to characterize infiltration
Vadose Zone JournalInfiltration regulates the movement and storage of water at the soil–atmosphere interface and is, therefore, a key component of many related physical and biogeochemical processes.
Christelle Basset +8 more
doaj +1 more source