Results 61 to 70 of about 7,768,428 (303)
Evaluating the efficiency of permeable pavement: Grass-filled pavers in the Netherlands
Nature-Based SolutionsPermeable pavements are implemented at more than thousand locations enabling rainfall infiltration and evapotranspiration of stormwater in The Netherlands. However, the efficiency has not been extensively tested.
Floris Boogaard +2 more
doaj +1 more source
Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy
Molecular Oncology, EarlyView.LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir +9 more
wiley +1 more source
USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival
Molecular Oncology, EarlyView.CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna +8 more
wiley +1 more source
Urban, Planning and Transport Research, 2014 Permeable pavements are specifically designed to promote the infiltration of stormwater through the paving surface in order to reduce run-off volumes and to improve water quality by removing sediment and other pollutants. However, research has shown that
Terry Lucke +2 more
doaj +1 more source
Seepage and water retention characteristics of fill in a construction site in Yan'an
Yantu gongcheng xuebao, 2018 With the urbanization in China, there are more and more projects involved with miscellaneous fill. In order to study the seepage and water retention characteristics of unsaturated soils, two kinds of tests are made.
ZHANG Long 1, CHEN Zheng-han 2, HU Sheng-xia 3, LIU Zheng-hong 1, YU Yong-tong 1, ZHENG Jian-guo 1
doaj +1 more source
Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
FEBS Open Bio, EarlyView.Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
John Cahoon Conducting an Infiltration Test on Bill Byars Land
, 1955 Photograph of John Cahoon conducting an Infiltration test on Bill Byars land south of water plant. The back of the photograph proclaims, "Infiltration test on Bill Byars land south of water plant. Joe Cahoon making test.
Hindman, F. G.
core
Cement-rock interaction : infiltration of a high-pH solution into a fractured granite core [PDF]
, 2010 Within the framework of the HPF project (Hyperalkaline Plume in Fractured Rock) at the Grimsel Test Site (Switzerland), a small scale core infiltration experiment was performed at the University of Bern.
Mäder, Urs K. +3 more
core +1 more source