Results 21 to 30 of about 4,487,147 (242)

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

A Provable Semi-Infinite Programming Approach for Solving Constrained Dynamic Games

open access: yesGames
Many engineering problems must account for the non-cooperative decisions and actions of multiple players. These problems can be modeled within a game-theoretic framework.
Tyler C. Gardner   +2 more
semanticscholar   +1 more source

Bandgap optimization of two-dimensional photonic crystals using semidefinite programming and subspace methods [PDF]

open access: yesJournal of Computational Physics, 2009
In this paper, we consider the optimal design of photonic crystal structures for two-dimensional square lattices. The mathematical formulation of the bandgap optimization problem leads to an infinite-dimensional Hermitian eigenvalue optimization problem ...
H. Men   +4 more
semanticscholar   +1 more source

Algorithmic principles of mathematical programming

open access: yes, 2002
Algorithmic Principles of Mathematical Programming investigates the mathematical structures and principles underlying the design of efficient algorithms for optimization problems.
Kern, Walter   +2 more
core   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

INCOMPLETE MARKETS IN INFINITE HORIZON: DEBT CONSTRAINTS VERSUS NODE PRICES [PDF]

open access: yes, 1995
The general equilibrium model with incomplete markets is here extended to infinite horizon economies populated by a finite number of infinitely lived agents.
Monique Florenzano   +3 more
core   +2 more sources

Air‐Pressure–Actuated Vibroacoustic Metamaterial With Tunable Bandgap: Design, Modeling, and Characterization

open access: yesAdvanced Engineering Materials, EarlyView.
This article presents the design, modeling, and characterization of air‐pressure–actuated programmable vibroacoustic metamaterials (PVAMM). The study focuses on leveraging air pressure to dynamically tune resonance frequencies for effective noise attenuation.
William Kaal   +2 more
wiley   +1 more source

APL programming without tears: it is time for a change [PDF]

open access: yes, 1993
Naeve P, Strohmeier B, Wolf P. APL programming without tears: it is time for a change. APL Quote Quad. 1993;24(1):185-189.To overcome the unreadability of traditional APL-code Knuth's idea of literate programming is adapted to APL.
Naeve, Peter   +5 more
core   +1 more source

Towards Defect Phase Diagrams: From Research Data Management to Automated Workflows

open access: yesAdvanced Engineering Materials, EarlyView.
A research data management infrastructure is presented for the systematic integration of heterogeneous experimental and simulation data required for defect phase diagrams. The approach combines openBIS with a companion application for large‐object storage, automated metadata extraction, provenance tracking and federated data access, thereby supporting ...
Khalil Rejiba   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy