Results 111 to 120 of about 380,262 (318)
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
On the impossibility of representing infinite utility streams [PDF]
, 2007 We show that, independently of the topology chosen on the set of all infinity utility streams, there is no Social Welfare Function preserving the von Weizsäcker’s overtaking criterion.
Núñez Sanz, Carmelo +5 more
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The development and validation of a tablet-based assessment battery of general cognitive ability
BMC PsychologyBackground Traditional cognitive assessments, often reliant on paper-and-pencil tests and professional evaluators, suffer from subjectivity and limited result discrimination.
Dong-ni Pan +10 more
doaj +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Solving Semi-Infinite Variational Inequalities
, 2006 The variational inequality problem arises in numerous contexts. In this dissertation, we consider solving a semi-infinite variational inequality problem, which is a variational inequality problem defined on a domain described by infinitely many ...
Ozcam, Burcu
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Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
A Short Note on the Infinite Decision Puzzle
This work draws on the Supertask literature1 in order to better understand the conceptual and physical possibility of an infinite decision puzzle presented by Barrett and Arntzenius (1999, 2002).
Garcia-Fronti, Javier
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Combating infinite state using ergo
, 2003 Symbolic transition systems can be used to represent infinite state systems in a finite manner. The modal logic FULL, defined over symbolic transition systems, allows properties over infinite state to be expressed, establishing necessary constraints on ...
Shankland, C +5 more
core +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Numerical experiments in semi-infinite programming [PDF]
, 1993 A quasi-Newton algorithm for semi-infinite programming using an L∞ exact penalty function is described, and numerical results are presented. Comparisons with three Newton algorithms and one other quasi-Newton algorithm show that the algorithm is very
Coope, I. D., Price, Christopher John
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