Results 51 to 60 of about 892 (270)
Nanoscale Spatial Organization of ARC High‐ and Low‐Order Assemblies at Excitatory Synapses
Advanced Science, EarlyView.ARC (Activity‐Regulated Cytoskeleton‐Associated protein) mediates synaptic plasticity by forming nanoscale assemblies in neurons. Using super‐resolution microscopy and time‐resolved anisotropy with targeted tagging, the study reveals low‐order ARC assemblies at synapses colocalizing with AMPARs, semi‐circular structures at endocytic zones, and 60–80 nm
Martina Damenti +13 more
wiley +1 more source
Orbit, 2017 This article asks what kind of relationship critics can posit between, on the one hand, David Foster Wallace’s personal library and marginalia and, on the other hand, his published works of fiction.
John Roache
doaj +2 more sources
Endogenous Engineering Reprograms Extracellular Vesicles for Enhanced Therapeutic Function
Advanced Science, EarlyView.This review explains how Extracellular vesicles‐producing cells can be endogenously engineered to load therapeutic proteins and nucleic acids. We summarize physiological and genetic strategies that harness native sorting pathways for selective cargo loading.
Jinghui Wang +10 more
wiley +1 more source
Ethics, Gesture and the Western
Performance Philosophy, 2017 This paper relates the Western Movie to Agamben’s implied gestural zone between intention and act. Film is important in the realisation of this zone because it was the first means of representation to capture the body in movement.
Michael Minden
doaj +1 more source
David Foster Wallace e Martin Heidegger. A Heideggerian Perspective of Infinite Jest
, 2014 In his celebrated novel Infinite Jest, David Foster Wallace makes some reference to Martin Heidegger and the question concerning technology. The aim of this article is to show the extent to which the novel can be regarded as a literary transposition of ...
Scarlato C
core +1 more source
Advanced Science, EarlyView.(a) The outstanding lubricative properties of natural articular cartilage arise from a composite coating composed of HA, lubricin, and phospholipids at its surface. Notably, lubricin facilitates the enrichment of synovial HA onto cartilage surfaces, and HA complexes with phospholipids, a key component to maintain extremely low friction under high ...
Yongan Lin +12 more
wiley +1 more source
Abjection and Empathy: The Shared Spaces and Blurred Boundaries of Infinite Jest
, 2014 In Infinite Jest, David Foster Wallace positions abjection in opposition to empathy. Both psychological phenomena derive from a relationship between two people, but abjection depends on a pushing away and empathy depends on a pulling toward.
Washburn, Emily
core +3 more sources
Advanced Science, EarlyView.Local stress concentration disrupts metabolic homeostasis and induces inflammation in the nucleus pulposus (NP), thereby accelerating intervertebral disc degeneration (IDD). A biomimetic HA/ChS hydrogel millimeter sphere (ChS@HM) is developed to enable synergistic stress dispersion and sustained hydration lubrication.
Ang Li +4 more
wiley +1 more source
The Inverted Nuke in the Garden: Archival Emergence and Anti-Eschatology in David Foster Wallace’s Infinite Jest [PDF]
, 2012 This essay historically situates David Foster Wallace’s Infinite Jest as a transitional text between the first and second nuclear ages. Written in the immediate wake of the Cold War, Infinite Jest complexly develops the nuclear trope’s fabulously textual
Bradley J. Fest
core +1 more source
Advanced Science, EarlyView.A self‐supervised multi‐view graph fusion framework integrates spatial multi‐omics, excelling in domain identification and denoising. It reconstructs spatial pseudo‐expression, jointly analyzes multi‐omics data, infers RNA velocity, predicts spatial omics features from single‐cell multi‐omics, and detects spatially dark genes and transcription factors,
Yuejing Lu +8 more
wiley +1 more source