Results 131 to 140 of about 109,495 (298)

Relativistic Corrections to the 1D Schrodinger Equation for the Infinite Potential Well

, 2019
In a previous note (1), we tried to develop an approach for dealing with relativistic corrections to the Schrodinger equation by considering the relativistic bound state wavefunction: Wrel(x) = Integral dprel f(prel) exp(i prel x) ((1)) with prel = p/sqrt(1-p*p/(m*m) where p is the nonrelativistic momentum.
openaire   +2 more sources

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Modern Physics Problem: Finite Well [PDF]

, 2002
In exercise is designed to study the finite square well and to show the shooting method works. Although the finite square-well potential problem is more realistic then the infinite well, it is difficult to solve because it yields transcendental equations.
Christian, Wolfgang; Belloni, Mario
core   +2 more sources

Axial gravitational normal modes of uniform density star in Anti-de Sitter spacetime

Nuclear Physics B
The article studies the dynamical behavior of axial gravitational perturbations of homogeneous stars in Anti-de Sitter spacetime. Because the radial coordinate r transforms into the tortoise coordinate y=y(r), obeying y(r=0)=0 and y(r ...
Kai Lin, Alan B. Pavan, Amilcar Rabelo De Queiroz, Elcio Abdalla   +3 more
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Astrocyte heterogeneity in brain metastases

Molecular Oncology, EarlyView.
Astrocytes emerge as pivotal regulators of metastatic colonization, survival, immune remodeling, and therapy response associated with an increasing heterogeneity that requires spatially and longitudinally resolved approaches to uncover regulatory programs and guide context‐specific therapies.
Carolina Hernández‐Oliver, Neibla Priego, Manuel Valiente   +2 more
wiley   +1 more source

Matrix Mechanics of a Particle in a One-Dimensional Infinite Square Well [PDF]

We solve the infinite potential well problem using the methods of Heisenberg's matrix mechanics. In addition to being of educational value, the matrix mechanics allows us to deal with various unphysical issues caused by this potential in a seemingly ...
Vedral, Vlatko
core   +1 more source

From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care

Molecular Oncology, EarlyView.
Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard, Flavie Bénard, Eva Billat, Margaux Le Guyon, Victoria Maltret, Laura Merlet, Chloé Astrid Walter, Tony Avril, Eric Chevet   +8 more
wiley   +1 more source

Continuous Variable Measurement-Device-Independent Quantum Certification

Physical Review X
Secure and reliable certification of quantum resources is a fundamental challenge in the advancement of next-generation quantum technologies, particularly as devices become more complex and integrated into practical applications, where parts of the ...
B. L. Larsen, A. A. E. Hajomer, P. Abiuso, S. Izumi, T. Gehring, J. S. Neergaard-Nielsen, A. Acín, U. L. Andersen   +7 more
doaj   +1 more source