Results 101 to 110 of about 109,495 (298)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Modified Heisenberg Commutation Relations and the Infinite-Square Well Potential: Some Simple Consequences [PDF]

We explore some consequences of modifying the usual Heisenberg commutation relations of two simple systems: first, the one-dimensional quantum system given by the infinite square-well potential, and second, the case of a gas of N non-interacting ...
José Mauricio Gonzalez, Mauricio Contreras González, Roberto Ortiz Herrera   +2 more
core   +5 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Gravity field due to a homogeneous oblate spheroid: Simple solution form and numerical calculations

Contributions to Geophysics and Geodesy, 2011
We present a simple derivation of the interior and exterior gravitational potentials due to oblate spheroid and also its gravity field components by using the fundamental solution of the Laplace equation in oblate spheroidal coordinates.
Milan HVOŽDARA, Igor KOHÚT
doaj   +1 more source

The Wiener-Hopf-Hilbert technique applied to problems in diffraction [PDF]

, 1999
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.A number of diffraction problems which have practical applications are examined using the Wiener-Hopf-Hilbert technique.
Barton, P.G., Barton, Peter
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Analysis of the infinite potential well models in the modern physics textbooks

European Journal of Physics
Abstract We investigate the infinite potential well model in five modern physics textbooks widely used in undergraduate courses. We find that the textbooks utilize mechanical systems and electrical circuits, incorporating metaphorical terms to introduce the model, but they do not provide a clear explanation of the quantum nature of ...
Joohye Lee, InHo Lee, Sangwoo Ha, Hyojun Seok   +3 more
openaire   +1 more source

Periodic systems in time: double-well potential [PDF]

, 2003
Time analysis of oscillations of a particle between wells in the one-dimensional double-well potential with infinite high outside walls, based on wave packet use and energy spectrum analysis, is presented.
Maydanyuk, Sergei P
core  

Piezoelectric and deformation potential effects of strain-dependent luminescence in semiconductor quantum well structures [PDF]

, 2017
The mechanism of strain-dependent luminescence is important for the rational design of pressure-sensing devices. The interband momentum-matrix element is the key quantity for understanding luminescent phenomena. We analytically solved an infinite quantum
Peng, Mingzeng, Zhai, Junyi, Willatzen, Morten, Wang, Zhong Lin, Zhang, Aihua   +4 more
core   +1 more source