Results 241 to 250 of about 216,697 (310)

Optically Switchable Fluorescence Enhancement at Critical Interparticle Distances

open access: yesAdvanced Theory and Simulations, EarlyView.
In this work, we present the results of a complete FDTD (Finite Difference Time Domain) model specifically tailored for the precise determination of critical interparticle distances yielding observable fluorescence enhancement. We further report an optical switch applied on a metal nanoparticle to actively control the radiative decay rate of a closely ...
Arda Gulucu, Emre Ozan Polat
wiley   +1 more source

Analysis of multi-wave solitary solutions of (2+1)-dimensional coupled system of Boiti-Leon-Pempinelli. [PDF]

open access: yesSci Rep
Ghazanfar S   +7 more
europepmc   +1 more source

NAD+‐Boosters Improve Mitochondria Quality Control In Parkinson's Disease Models Via Mitochondrial UPR

open access: yesAdvanced Science, EarlyView.
Treatment of MPTP‐incubated cells with NAD+‐boosters increase the UPRmt/mitophagy‐related mitochondria quality control (MQC). Disturbed plasma UPRmt‐mitophagy‐mediated MQC profiles in PD patient samples. NMN inhibits motor deficit and forestalls neuropathology phenotypes of PD mice, which is required the atf4‐medicated UPRmt pathway.
Shuoting Zhou   +16 more
wiley   +1 more source

Tryptophan Metabolite Indole‐3‐Aldehyde Induces AhR and c‐MYC Degradation to Promote Tumor Immunogenicity

open access: yesAdvanced Science, EarlyView.
Tryptophan metabolite Indole‐3‐aldehyde (I3A) downregulates cytosolic AhR and p‐ERK/c‐MYC proteins, together enhancing STAT3 phosphorylation and tumor immunogenicity. Overexpression of the Trp metabolic enzyme interleukin‐4‐induced gene‐1 (IL4I1) in tumor cells increases intracellular levels of I3A and enhances tumor immunogenicity.
Lei Cui   +19 more
wiley   +1 more source

Succinate Dehydrogenase Subunit A (SDHA) Mediated Microglia Extracellular Traps Formation Participating in Cerebral Ischemic Reperfusion Injury

open access: yesAdvanced Science, EarlyView.
This study investigates the mechanism of succinate dehydrogenase (SDH)‐mediated succinate oxidation in microglia extracellular traps (MiETs) formation and neuronal injury after cerebra I/R injury. Dimethyl malonate (DMM), a competitive SDH inhibitor, could reduce MiETosis by inhibiting succinate oxidation and mtROS production during reperfusion ...
Lili Zhao   +21 more
wiley   +1 more source

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