Results 31 to 40 of about 10,181,115 (247)

Infinitely Many Solutions for a Class of Fractional Boundary Value Problems with Nonsmooth Potential [PDF]

open access: yes, 2013
We establish the existence of infinitely many solutions for a class of fractional boundary value problems with nonsmooth potential. The technical approach is mainly based on a result of infinitely many critical points for locally Lipschitz ...
Kaimin Teng
core   +1 more source

Infinitely many positive solutions for a double phase problem

open access: yesBoundary Value Problems, 2020
This paper is concerned with the existence of infinitely many positive solutions to a class of double phase problem. By variational methods and the theory of the Musielak–Orlicz–Sobolev space, we establish the existence of infinitely many positive ...
Bei-Lei Zhang, Bin Ge, Gang-Ling Hou
doaj   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Infinitely many periodic solutions for a second-order nonautonomous system

open access: yes, 2003
The existence of infinitely many solutions for a second-order nonautonoumous system was investigated. Some multiplicity results for problem (P) under very different assumptions on the potential G were established.
livrea, Roberto   +2 more
core   +1 more source

Ground state solutions and infinitely many solutions for a nonlinear Choquard equation

open access: yesBoundary Value Problems, 2021
In this paper we study the existence and multiplicity of solutions for the following nonlinear Choquard equation: − Δ u + V ( x ) u = [ | x | − μ ∗ | u | p ] | u | p − 2 u , x ∈ R N , $$\begin{aligned} -\Delta u+V(x)u=\bigl[ \vert x \vert ^{-\mu }\ast ...
Tianfang Wang, Wen Zhang
doaj   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

open access: yesFEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez   +6 more
wiley   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

open access: yesFEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen   +5 more
wiley   +1 more source

Infinitely many radial solutions for Kirchhoff-type problems in RN

open access: yes, 2010
In this paper, we concern with a class of Kirchhoff-type problems in RN. By using the Fountain Theorem we obtain three existence results of infinitely many radial solutions for the ...
Wu, Xian, Jin, Jiahua
core   +1 more source

Superlinear nonlocal fractional problems with infinitely many solutions [PDF]

open access: yes, 2015
In this paper we study the existence of infinitely many weak solutions for equations driven by nonlocal integrodifferential operators with homogeneous Dirichlet boundary conditions. We consider different superlinear growth assumptions on the nonlinearity,
MOLICA BISCI G   +2 more
core   +1 more source

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