Results 271 to 280 of about 90,432 (374)

NETosis and pyroptosis of immune cells in sepsis. [PDF]

open access: yesJ Transl Int Med
Kashif AM, Ouyang Y, Li Y, Pan B.
europepmc   +1 more source

Oxidative Stress Modulation and Antileishmanial Activity of Salvinia auriculata

open access: yesChemistry &Biodiversity, EarlyView.
Ethanolic extract of Salvinia auriculata showed significant antioxidant and antileishmanial activities. Salviniside II, the major metabolite, was isolated, structurally characterized, and evaluated, but exhibited weaker antiparasitic effects when compared to the whole extract.
Augusto César Rodrigues   +6 more
wiley   +1 more source

Comparative Analysis of Septin Modifiers, Forchlorfenuron and UR214‐9, on Mitochondrial Fragmentation and Lytic Cell Death

open access: yesCytoskeleton, EarlyView.
ABSTRACT Septins are conserved GTP‐binding proteins that play key roles in cell division, mitochondrial dynamics and immune responses. Despite their importance to human health, pharmacological compounds to modify septins remain limited. Forchlorfenuron (FCF) was the first small molecule identified to modify septins, disrupting their organisation and ...
Dominik Brokatzky   +4 more
wiley   +1 more source

Endotoxin tolerance inhibits NLRP3 inflammasome activation in macrophages of septic mice by restoring autophagic flux through TRIM26. [PDF]

open access: yesOpen Med (Wars)
Yang Y   +11 more
europepmc   +1 more source

The NLRP3 Inflammasome Mediates In Vivo Innate Immunity to Influenza A Virus through Recognition of Viral RNA

open access: green, 2009
Irving C. Allen   +8 more
openalex   +2 more sources

The Role of the Inflammasome in Nonmyeloid Cells [PDF]

open access: green, 2010
Amir S. Yazdi   +2 more
openalex   +1 more source

Nonsteroidal Anti‐Inflammatory Drugs as Modulators of Cation Channels: Fenamates Repurposing in Channelopathies

open access: yesChemMedChem, EarlyView.
Beyond their established role as nonsteroidal anti‐inflammatory drugs (NSAIDs), fenamates (niflumic, flufenamic, mefenamic, meclofenamic, and tolfenamic acids) have recently been identified as modulators of cationic ion channels. This review highlights their differential effects on ion channel activity and explores their potential for repurposing in ...
Paola Laghetti   +4 more
wiley   +1 more source

Diverse functions of NLRP3 inflammasome in PANoptosis and diseases. [PDF]

open access: yesCell Death Discov
Jiang Y   +7 more
europepmc   +1 more source

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