Results 301 to 310 of about 90,432 (374)

Immune dysregulation as a key driver of peripartum cardiomyopathy – an exploratory advanced imaging and biomarker study

European Journal of Heart Failure, EarlyView.
Physiological postpartum remodelling and the pathological processes involved in peripartum cardiomyopathy (PPCM). 18FDG‐PET‐CT, 18F‐fluorodeoxyglucose positron emission tomography‐computed tomography; CCL3, chemokine (C‐C motif) ligand 3; CMR, cardiovascular magnetic resonance; CRP, C‐reactive protein; CSF‐1, colony‐stimulating factor 1; CXCL10 ...
Julian Hoevelmann, Charle Viljoen, Tessa Kotze, Carlos Libhaber, Stephen Jermy, Morné Kahts, Fareda Jakoet‐Bassier, Petronella Samuels, Olivia Briton, Lynette Cilliers, Denise Hilfiker‐Kleiner, Peter van der Meer, Michael Böhm, Ntobeko A.B. Ntusi, Karen Sliwa   +14 more
wiley   +1 more source

Is pyroptosis a brake or an accelerator in the fate of the tumor? [PDF]

Cell Death Dis
Hou Y, Li W, Yang J, Yu H, Wang C, Li Y, Lv S, Zhang L.   +7 more
europepmc   +1 more source

Atrial cardiomyopathy: From healthy atria to atrial failure. A clinical consensus statement of the Heart Failure Association of the ESC

European Journal of Heart Failure, EarlyView.
The diagnosis of atrial cardiomyopathy (AtCM) requires electrical atrial dysfunction, with evidence of either mechanical atrial dysfunction, atrial enlargement, or excessive atrial fibrosis. The diagnostic cut‐points presented are for standard electrocardiogram and echocardiogram studies (see Figure 1 for further detail).
Jerremy Weerts, Otilia Țica, Julia Aranyo, Christian Basile, Angelina Borizanova‐Petkova, Josip Andjelo Borovac, Massimiliano Camilli, Martin Eichenlaub, Emiliano Fiori, Tim Van Loon, Coenraad Withaar, Diana Zakarkaitė, Matthias D. Zink, Marianna Adamo, Alberto Aimo, Elena Arbelo, Felipe Bisbal Van Bylen, Dimitrios T. Farmakis, Dobromir Dobrev, Jelena Čelutkienė, Michael Böhm, Andrew Coats, Marco Metra, Giuseppe Rosano, Frank Ruschitzka, Antoni Bayes‐Genis, Dipak Kotecha   +26 more
wiley   +1 more source

Role of inflammasomes in cancer immunity: mechanisms and therapeutic potential. [PDF]

J Exp Clin Cancer Res
Singh V, Ubaid S, Kashif M, Singh T, Singh G, Pahwa R, Singh A.   +6 more
europepmc   +1 more source

Modulating Lysine Crotonylation in Ulcerative Colitis Maintains Mitochondrial Homeostasis

Exploration, EarlyView.
NaCr promotes KCr to impede the inflammatory progression of ulcerative colitis. KCr induces mitophagy by activating the PINK1/PARKIN pathway to restrict NLRP3 inflammasome activation, thereby decreasing the production and release of various inflammatory cytokines, such as IL‐1β and TNF‐α. KCr induces mitophagy and inhibits NLRP3 inflammasome activation
Tongtong Liu, Binyan Lin, Ying Zhang, Jiayu Su, Xiaochao Hu, Xuan Wang, E‐Hu Liu, Shijia Liu   +7 more
wiley   +1 more source

Communication initiated by hepatocytes: The driver of HSC activation and liver fibrosis. [PDF]

Hepatol Commun
Lan R, Lin J, Chen S, Lu Z, Gong Y, Tan S, Liu X, He W.   +7 more
europepmc   +1 more source

Immunomodulatory Nanozymes Eradicate Intracellular Infections and Rescue Immunoparalysis for Treating Multidrug‐Resistant Bacterial Sepsis

Exploration, EarlyView.
Immunomodulatory nanozymes enable in situ macrophages engineering and orchestrate systemic innate‐adaptive immune response to eradicate intracellular bacteria and rescue immunoparalysis for treating multidrug‐resistant bacterial sepsis. ABSTRACT Sepsis and their sequelae are the leading causes of death in intensive care units, with limited therapeutic ...
Xuancheng Du, Zhenzhen Dong, Yan Yan, Yuan Gong, Meili Yuan, Chengtai Ma, Lingqi Xu, Yuanyuan Qu, Minhan Qu, Peng Pan, Weifeng Li, Wenyan Hao, Yingyi Yang, Xiangdong Liu, Mingwen Zhao, Zhenjiang Bai, Jiang Huai Wang, Jian Wang, Yong‐Qiang Li, Huiting Zhou   +19 more
wiley   +1 more source

Neutrophilic asthma may not be a distinct endotype. [PDF]

ERJ Open Res
Bhalla A, Sehmi R, Nair P, Mukherjee M.
europepmc   +1 more source

The Inflammasome Component Nlrp3 Impairs Antitumor Vaccine by Enhancing the Accumulation of Tumor-Associated Myeloid-Derived Suppressor Cells

, 2010
Hendrik W. van Deventer, Joseph E. Burgents, Qing Wu, Rita-Marie T. Woodford, W. June Brickey, Irving C. Allen, Erin McElvania, Jonathan S. Serody, Jenny P.‐Y. Ting   +8 more
openalex   +1 more source

Kaempferol Alleviates Acrolein‐Induced Lung Injury In Vitro and In Vivo by Binding to Peli2 and Disrupting the Peli2‐NLRP3 Interaction

Food Frontiers, EarlyView.
Abstract Acrolein (ACR) is a highly toxic agent that induces lung inflammation and causes acute lung injury (ALI). However, effective treatments for ACR‐induced ALI are currently lacking. We investigated the protective effects of kaempferol (Kae) against ACR‐induced ALI using in vitro (HBE and BEAS‐2B cells) and in vivo murine models (male C57BL/6 mice)
Juanjuan Ma, Zhao Yin, Jie Zheng, Xingyou Mo, Shaoji Li, Hua Liu, Shiyi Ou   +6 more
wiley   +1 more source