Results 331 to 340 of about 90,432 (374)

Stigmasterol attenuates atherosclerosis by inhibiting inflammatory signaling and foam cell formation

open access: yesiMetaOmics, EarlyView.
Stigmasterol mitigates atherosclerotic plaque formation by modulating foam cell phenotypic alterations and cholesterol metabolism. Stigmasterol inhibits inflammatory CD86+ macrophage polarization via the NF‐κB/NLRP3 pathway and downregulates CD68 expression in smooth muscle cells (SMCs), contributing to reduced vascular inflammation.
Baiyi Lu   +10 more
wiley   +1 more source

Astragaloside IV Alleviates Ulcerative Colitis Progression by Inhibiting WDR5‐Mediated ENO1 H3K4me3 Modification

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Ulcerative colitis (UC) has become a prevalent global health concern. This study scrutinized the influence of Astragaloside IV (ASI) on DSS‐induced UC, with particular emphasis on the role of WDR5 in mediating ENO1 expression. The therapeutic efficacy of ASI was assessed in a mouse model of UC by evaluating disease activity index, pathology ...
Su‐Xiao Wu   +3 more
wiley   +1 more source

P62 inhibits IL-1β release during <i>Salmonella</i> Typhimurium infection of macrophages. [PDF]

open access: yesFront Cell Infect Microbiol
Hos NJ   +6 more
europepmc   +1 more source

Inflammasomes and Signaling Pathways: Key Mechanisms in the Pathophysiology of Sepsis. [PDF]

open access: yesCells
Saavedra-Torres JS   +10 more
europepmc   +1 more source

Cross-talk between NLRP3 and AIM2 inflammasomes in macrophage activation by LPS and titanium ions. [PDF]

open access: yesMol Med
Carrillo-Gálvez AB   +9 more
europepmc   +1 more source

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