Unleashing the potential of exercise: conquering cardiovascular disease by targeting inflammasome activation. [PDF]
Xiang L, Su Z.
europepmc +1 more source
Stigmasterol attenuates atherosclerosis by inhibiting inflammatory signaling and foam cell formation
Stigmasterol mitigates atherosclerotic plaque formation by modulating foam cell phenotypic alterations and cholesterol metabolism. Stigmasterol inhibits inflammatory CD86+ macrophage polarization via the NF‐κB/NLRP3 pathway and downregulates CD68 expression in smooth muscle cells (SMCs), contributing to reduced vascular inflammation.
Baiyi Lu +10 more
wiley +1 more source
Editorial: Innate immune dysregulation: a driving force of autoimmunity and chronic inflammation. [PDF]
Akbarzadeh R +3 more
europepmc +1 more source
ABSTRACT Ulcerative colitis (UC) has become a prevalent global health concern. This study scrutinized the influence of Astragaloside IV (ASI) on DSS‐induced UC, with particular emphasis on the role of WDR5 in mediating ENO1 expression. The therapeutic efficacy of ASI was assessed in a mouse model of UC by evaluating disease activity index, pathology ...
Su‐Xiao Wu +3 more
wiley +1 more source
P62 inhibits IL-1β release during <i>Salmonella</i> Typhimurium infection of macrophages. [PDF]
Hos NJ +6 more
europepmc +1 more source
Inflammasomes and Signaling Pathways: Key Mechanisms in the Pathophysiology of Sepsis. [PDF]
Saavedra-Torres JS +10 more
europepmc +1 more source
Role of inflammasomes in acute respiratory distress syndrome. [PDF]
Flower L +3 more
europepmc +1 more source
Effects of exercise on neuroinflammation in age-related neurodegenerative disorders. [PDF]
Su Y, Su Z.
europepmc +1 more source
Cross-talk between NLRP3 and AIM2 inflammasomes in macrophage activation by LPS and titanium ions. [PDF]
Carrillo-Gálvez AB +9 more
europepmc +1 more source

