Results 171 to 180 of about 488,838 (371)

Advances in Microfluidic Cochlea‐On‐A‐Chip

Advanced Science, EarlyView.
This review systematically examines diverse cell sources for inner ear organoids and outlines stepwise induction protocols. Furthermore, it discusses current applications and prospective developments of cochlea‐on‐a‐chip technologies in areas such as deafness modeling, mechanistic studies, and drug evaluation, with particular focus on gene‐therapy drug
Tian Shen, Shanying Han, Weiwei He, Wen Yang, Xinghua Tang, Xiaolong Zhao, Xinghong Liu, Zhenhua Shao, Lin Cheng, Yu Zhao, Jiangang Fan   +10 more
wiley   +1 more source

Deep Learning for Classification of Inflammatory Bowel Disease Activity in Whole Slide Images of Colonic Histopathology [PDF]

arXiv
Grading inflammatory bowel disease (IBD) activity using standardized histopathological scoring systems remains challenging due to resource constraints and inter-observer variability. In this study, we developed a deep learning model to classify activity grades in hematoxylin and eosin-stained whole slide images (WSIs) from patients with IBD, offering a
arxiv  

Mitigation of Experimental Inflammatory Bowel Disease in Guinea Pigs by Selective Elimination of the Aerobic Gram-Negative Intestinal Microflora

, 1974
D. van der Waaij, Bennett J. Cohen, Miriam R. Anver   +2 more
openalex   +1 more source

Urinary crystalloid excretion in patients with inflammatory bowel disease [PDF]

, 1970
Richard I. Breuer, E. A. Gelzayd, J. K. Kirsner   +2 more
openalex   +1 more source

FGF2 Mediated USP42‐PPARγ Axis Activation Ameliorates Liver Oxidative Damage and Promotes Regeneration

Advanced Science, EarlyView.
USP42 is identified as a novel DUB of PPARγ in hepatocytes. USP42 mediated PPARγ deubiquitylation determines its transcriptional preference on proliferative and redox balance genes. USP42 knockdown exacerbates liver damage and delays regeneration. FGF2 is the upstream signal that initiates and activates the USP42‐PPARγ axis.
Nanfei Yang, Qiang Tian, Zhenli Lei, Shuxin Wang, Nan Cheng, Zhen Wang, Xianqin Jiang, Xuqun Zheng, Wenjing Xu, Minyan Ye, Longwei Zhao, Meiyun Wen, Jianlou Niu, Weijian Sun, Pingping Shen, Zhifeng Huang, Xiaokun Li   +16 more
wiley   +1 more source

The role of mutants in the spatio-temporal progression of inflammatory bowel disease: three classes of permanent form travelling waves [PDF]

arXiv
Despite its high prevalence and impact on the lives of those affected, a complete understanding of the cause of inflammatory bowel disease (IBD) is lacking. In this paper, we investigate a novel mechanism which proposes that mutant epithelial cells are significant to the progression of IBD since they promote inflammation and are resistant to death.
arxiv  

Usefulness of Rectal Biopsy in Inflammatory Bowel Disease

, 1977
Michael J. Goodman, Joseph B. Kirsner, Robert H. Riddell   +2 more
openalex   +1 more source

Serum lysozyme in inflammatory bowel and coeliac disease. [PDF]

, 1976
Elias Mallas, J M Terry, P Asquith, W. T. Cooke   +3 more
openalex   +1 more source

Artesunate Inhibits Neointimal Hyperplasia by Promoting IRF4 Associated Macrophage Polarization

Advanced Science, EarlyView.
This study shows that macrophage interferon regulatory factor 4 (IRF4) improved arterial injury‐induced neointimal hyperplasia by promoting of M2 polarization via up‐regulating krüppel‐like factor 4 (KLF4) in rodent and nonhuman primate models. Notably, artesunate is identified as a potent inducer of IRF4 in macrophages, and proposed as a promising ...
Jinlin Miao, Yule Yong, Zhaohui Zheng, Kui Zhang, Wei Li, Jiayi Liu, Siyi Zhou, Juan‐juan Qin, Haoyang Sun, Yatao Wang, Xianghui Fu, Xing Luo, Siyu Chen, Zhi‐Gang She, Jingjing Cai, Ping Zhu   +15 more
wiley   +1 more source

Fecal Radioiodide Excretion Following Intravenous Injection of 131I-Albumin and 125I-Immunoglobulin G in Chronic Inflammatory Bowel Disease.

, 1975
S. Jarnum, Kurt Birger Jensen
openalex   +1 more source