Results 181 to 190 of about 368,931 (281)

P654 Advances in optimalisation of therapeutic drug monitoring using mucosal TNF expression and anti-TNF concentration in patients with inflammatory bowel disease treated with biologicals: Preliminary results from a single-centre study [PDF]

, 2018
Klaudia Farkas, Gréta Elekes, D Kata, Imre Földesi, Steven M. Lada, Tamás Ferenci, Tamara Madácsy, Mariann Rutka, Anita Bálint, Renáta Bor, Anna Fábián, Ágnes Milassin, Zoltán Szepes, Ferenc Nagy, József Maléth, Tamás Molnár   +15 more
openalex   +1 more source

Targeted Inhibition of CD74+ Macrophages by Luteolin via CEBPB/P65 Signaling Ameliorates Osteoarthritis Progression

Advanced Science, EarlyView.
This study identifies CD74⁺ macrophages as key drivers of synovial inflammation in osteoarthritis (OA). The flavonoid luteolin is predicted to inhibit this pathway by blocking Nuclear Factor Kappa‐light‐chain‐enhancer of Activated B cells (NF‐κB) signaling. To enhance delivery, a targeted nanoplatform (MDSPL) is developed.
Rui Peng, Bo Yu, Lei Zhang, Zhaowen Xue, Lutian Yao, Qingjun Yang, Zitao Liu, Sizhi Wu, Yongquan Huang, Xiaofei Zheng, Huiying Guo, Songwei Huan, Tao Jiang, Huajun Wang, Yulong Wei, Tao Gui   +15 more
wiley   +1 more source

Management of Inflammatory Bowel Disease with History of Cancer. [PDF]

Cancers (Basel)
Annese V, Parisi M, Cinque S, Cappellini A, Biamonte P, Dell'Anna G, Testoni SGG, Annunziata ML.   +7 more
europepmc   +1 more source

Performance of Eight Infliximab Population Pharmacokinetic Models in a Cohort of Dutch Children with Inflammatory Bowel Disease [PDF]

Nanja Bevers, Ron J. Keizer, Dennis R. Wong, Arta Aliu, Marieke Pierik, Luc J. J. Derijks, Patrick F. van Rheenen   +6 more
openalex   +1 more source

Taurocholic Acid Is Associated With Disturbed Functional Connectivity in the Hippocampus of Patients With Depression

Advanced Science, EarlyView.
This study identifies elevated taurocholic acid (TCA) in Major Depressive Disorder patients. Gut microbiome‐associated TCA impairs hippocampal neurogenesis, triggers microglia activation, and elicits depression‐like behavior in mice via the S1PR2. In patients, functional neuroimaging reveals that serum TCA levels correlate with altered functional ...
Xiaoying Cai, Taipeng Sun, Mengzhen Feng, Gang Chen, Junchi Zhou, Hong Zhuang, Dan Wang, Ying Chen, Zhen Cheng, Zhi Xu, Xiao Zheng, Xueli Zhang, Yonggui Yuan   +12 more
wiley   +1 more source

Pyoderma Gangrenosum as the First Manifestation of Inflammatory Bowel Disease: A Case Report. [PDF]

Case Rep Gastrointest Med
Nguyen NH, Tran TT, Khuc TT, Lo YT, Doan HT, Nguyen HV, Nguyen LC.   +6 more
europepmc   +1 more source

Exclusive Breastfeeding Drives AMPK‐Dependent Thermogenic Memory in BAT and Promotes Long‐Term Metabolic Benefits in Offspring

Advanced Science, EarlyView.
Exclusive breastfeeding establishes a thermogenic memory in brown adipose tissue by activating the HIF1AN/AMPK/α‐ketoglutarate axis via milk‐derived extracellular vesicles enriched in miR‐125a‐5p. This programming preserves metabolic health, while αKG supplementation restores BAT function under mixed feeding, offering strategies to mitigate the ...
Ningxi Wu, Anwen Yin, Xiang Yu, Mingxin Wang, Jiahui Zhang, Kerong Liu, Yutong Hou, Minkai Cao, Yiting Zhang, Xiaoxiao Zhang, Yao Gao, Xirong Guo, Le Zhang, Yun Li   +13 more
wiley   +1 more source

Vedolizumab in inflammatory bowel disease: pharmacokinetics and the role of immunomodulator co-therapy. [PDF]

Therap Adv Gastroenterol
Pudipeddi A, Chaemsupaphan T, Arzivian A, Kim YS, Paramsothy S, Kariyawasam V, Leong RW.   +6 more
europepmc   +1 more source

Biomarker discovery in inflammatory bowel diseases

, 2018
Rahul Kalla
openalex   +1 more source

Intestinal inflammation markers in inflammatory bowel disease

, 2018
Abdullatif Alomair, Ayman Alswayeh, Abrar Alhazmi, Abdullah A. Al‐Shammari, Salma Alsaffar, Abrar Falamarzi, Moath Mohammad Alothman, Lujain Rayes, Mohammed Alkhathami, Ali Alhamidah   +9 more
openalex   +2 more sources