Results 261 to 270 of about 1,295,913 (316)
Mechanistic evidence for dibutyl phthalate as an environmental trigger for inflammatory bowel disease. [PDF]
iScienceYuan H, Chen G, Sun X, Yu J.
europepmc +1 more source
Advanced Science, EarlyView.This study shows that Salmonella VNP20009 recruits pro‐tumor neutrophils that reduce its anticancer efficacy. Combining VNP with amodiaquine selectively eliminates these neutrophils by targeting glutathione reductase. A GR‐shRNA‐loaded VNP strain was further developed, demonstrating an innovative strategy integrating drug repurposing with synthetic ...
Wanfa Dong +13 more
wiley +1 more source
Coagulopathy and platelet abnormalities in patients with inflammatory bowel disease. [PDF]
Korean J Intern MedKim DS, Moon W.
europepmc +1 more source
Advanced Science, EarlyView.RvD5 effectively alleviates UC by inhibiting STAT1 signaling to reduce CXCL8 expression in colonic epithelial cells via activation of GPR101, which subsequently decreases the infiltration of neutrophils in the colonic mucosal epithelium. Epimedin A1, a natural allosteric inhibitor of 5‐LOX, demonstrates potential as a therapeutic agent for UC by ...
Pengxiang Guo +9 more
wiley +1 more source
Research progress in molecular targeted therapy for inflammatory bowel disease. [PDF]
J Transl MedLiu N, Pan C, Qu L.
europepmc +1 more source
Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy
Advanced Science, EarlyView.Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong +5 more
wiley +1 more source
Physical Activity Improves Quality of Life in Patients With Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis. [PDF]
J Cachexia Sarcopenia MuscleKasznár E +10 more
europepmc +1 more source