Results 271 to 280 of about 1,107,019 (331)

Optimising Monoclonal Antibody Drug Development for Inflammatory Bowel Disease. [PDF]

Clin Exp Gastroenterol
Colwill M, Honap S, Danese S, Peyrin-Biroulet L.   +3 more
europepmc   +1 more source

Marital Idiopathic Inflammatory Bowel Disease Crohnʼs Disease in a Husband and Wife

, 1988
C. J. W. Murray, A. B. R. Thomson
openalex   +1 more source

KLK1 as an Epithelial‐Specific Brake Inhibits Colorectal Tumorigenesis by Suppressing B1R‐Mediated Fibroblast Phenotypic Transition

Advanced Science, EarlyView.
KLK1 downregulation disrupts the intestinal mucosal barrier and impairs kallikrein‐kinin signaling, thereby reducing Lys‐des‐Arg9‐BK production. This enhances B1R activation on ADAMDEC1⁺ fibroblasts, promoting inflammation and extracellular matrix (ECM) remodeling. The resulting iCAFs promote colorectal cancer progression, highlighting a novel KLK1‐B1R
Lisha Zhou, Meijing Wang, Shunji Liu, Limei Gu, Shijia Liu, Qianming Du, Tianyi Zhang, Yinuo Ma, Lixin Zhao, Jiaming Wang, Qiang Xu, Tingsheng Ling, Haibo Cheng, Hongqi Chen, Yang Sun   +14 more
wiley   +1 more source

Pain experience of people with inflammatory bowel disease: a qualitative study. [PDF]

BMJ Open Gastroenterol
Beames C, Azadi A, Williams ACC, ADVANTAGE Consortium.   +3 more
europepmc   +1 more source

Cell Fate Determination and Lineage Tracing: Technological Evolution and Multidimensional Applications

Advanced Science, EarlyView.
This figure is a candidate for the cover image. It shows a whole‐mount fluorescent image of lymphatic vessels (red) in the heart of an adult Cdh5‐Dre; Prox1‐RSR‐CreER; Rosa26‐tdT mouse. Image courtesy of Ximeng Han. Abstract Cell fate determination is a fundamental process in multicellular development.
Hui Chen, Zhicong Liu, Qiang Shu, Bin Zhou   +3 more
wiley   +1 more source

Cerebral Vein Sinus Thrombosis, An Unusual Complication of Inflammatory Bowel Disease. [PDF]

Eur J Case Rep Intern Med
Yehia A, Mudege T, Hoque S.
europepmc   +1 more source

Succinic Acid‐Induced Macrophage Endocytosis Promotes Extracellular Vesicle‐Based Integrin Beta1 Transfer Accelerating Fibroblast Activation and Sepsis‐Associated Pulmonary Fibrosis

Advanced Science, EarlyView.
Lipopolysaccharide (LPS) stimulates the production of succinic acid in lung tissue, which promotes macrophages endocytosis and the formation of multivesicular bodies (MVBs). These MVBs release profibrotic extracellular vesicles (EVs), facilitating the transfer of integrin beta1 (ITGβ1) transfer and subsequently activating fibroblasts, thereby ...
Wenyu Yang, Ri Tang, Yang Zhou, Jinquan Zhang, Shuya Mei, Yawen Peng, Xi Huang, Shunpeng Xing, Yuan Gao, Qiaoyi Xu, Zhengyu He   +10 more
wiley   +1 more source

Self-management experiences of Chinese patients with inflammatory bowel disease: Patients' perspective. [PDF]

Medicine (Baltimore)
Zheng Y, Zhu T, Zhu D, Zhou Y.
europepmc   +1 more source

Big Data and AI‐Powered Modeling: A Pathway to Sustainable Precision Animal Nutrition

Advanced Science, EarlyView.
This review summarizes the current landscape of big data and AI‐powered modeling in animal nutrition, covering techniques including intelligent data acquisition, data augmentation, explainable machine learning, heuristic algorithms, and life cycle assessment‐based sustainability evaluation.
Shuai Zhang, Changhua Lai, Jinbiao Zhao, Junjun Wang   +3 more
wiley   +1 more source