Results 291 to 300 of about 1,342,022 (369)

Therapeutic Reprogramming of Glioblastoma Phenotypic States Using Multifunctional Heparin Nanoparticles

Advanced Science, EarlyView.
This study presents heparin‐derived nanoparticles (HP‐NPs) as a novel precision medicine platform that combines therapeutic and delivery functions. HP‐NPs target drug‐resistant glioblastoma stem cells, reprogramming them into a drug‐sensitive phenotype and significantly reducing tumor progression.
Vadim Le Joncour, Austin D. Evans, Camilla Karoliina Bergström, Vignesh Kumar Rangasami, Sumanta Samanta, Nithiyanandan Krishnan, Yuji Teramura, Bo Nilsson, Patricia Hedenqvist, Elin Manell, Jons Hilborn, Marianne‐Jensen Waern, Oommen P. Varghese, Pirjo Laakkonen, Oommen P. Oommen   +14 more
wiley   +1 more source

Asian-Pacific perspectives on the management of very early-onset inflammatory bowel disease. [PDF]

Intest Res
Takeuchi I, Arai K, Tanpowpong P, Lai MW, Day AS, Lee WS, Huang JG, Calixto-Mercado KS, Sum Wong RM, Alvi MA, Grover Z, Shim JO, Poddar U.   +12 more
europepmc   +1 more source

Stress‐Induced Activation of Prolactin‐NR4A1‐Midkine Axis Exacerbates Skin Inflammation

Advanced Science, EarlyView.
Chronic psychological stress activates prolactin signaling to reprogram dermal fibroblasts into APCDD1+ inflammatory effectors via NR4A1, driving midkine secretion. This paracrine hub amplifies keratinocyte proliferation and immune recruitment, thus exacerbating skin inflammation.
Zhiguo Li, Huiyi Quan, Wanting Liu, Jiaoling Chen, Mengyang Chu, Xin Tang, Ke Xue, Xuan Liu, Jingyi Ma, Yaxing Bai, Ruina Dong, Bing Li, Junfeng Hao, Wei Guo, Qingyang Li, Erle Dang, Johann E Gudjonsson, Gang Wang, Shuai Shao   +18 more
wiley   +1 more source

Correction to: Novel outcomes in inflammatory bowel disease. [PDF]

J Crohns Colitis
europepmc   +1 more source

Mucinous adenocarcinoma of the rectum masquerading as inflammatory bowel disease-a case report. [PDF]

J Surg Case Rep
Zhu JL, Gao HJ, Wang LH, Yin ZT.
europepmc   +1 more source

A Novel FGFR3‐Targeting Antibody‐Drug Conjugate Induces Tumor Cell Apoptosis through the cGAS–STING Pathway in Bladder Cancer

Advanced Science, EarlyView.
LZU‐WZLYCS01 is a novel FGFR3‐targeting ADC for bladder cancer with 7‐ethyl‐9‐fluorocamptothecin (A2) as its cytotoxic payload. LZU‐WZLYCS01 intracellularly releases A2, which targets MAD2L1 to activate the cGAS‐STING pathway and induce tumor cell apoptosis.
Shu Cui, Xiongfei Luo, Guangrui Fan, Jingqi Jiang, Yingru Wang, Enguang Yang, Jinpeng Ma, Ze Zhang, Yuhan Wang, Juan Wang, Dengtuo Wang, Hanzhang Wang, Liang Cheng, Junqiang Tian, Zhilong Dong, Yingqian Liu, Zhiping Wang   +16 more
wiley   +1 more source

Effectiveness and safety of the recombinant zoster vaccine in adults aged ≥50 years with inflammatory bowel disease. [PDF]

Hum Vaccin Immunother
Tseng HF, Sy LS, Rayens E, Ackerson BK, Ku JH, Wu J, Luo Y, Cheng Y, Patel AR, Solano Z, De Jesus J, Amundsen B, Florea A, Chmielewski-Yee E, Oraichi D, Seifert H, Yun H, Qian L.   +17 more
europepmc   +1 more source

Wearable and Implantable Devices for Continuous Monitoring of Muscle Physiological Activity: A Review

Advanced Science, EarlyView.
Recent advances in materials and device engineering enable continuous, real‐time monitoring of muscle activity via wearable and implantable systems. This review critically summarizes emerging technologies for tracking electrophysiological, biomechanical, and oxygenation signals, outlines fundamental principles, and highlights key challenges and ...
Zhengwei Liao, Ata Golparvar, Mohammad Javad Bathaei, Filipe Arroyo Cardoso, Clementine M. Boutry   +4 more
wiley   +1 more source

Symptom clusters in inflammatory bowel disease: a scoping review. [PDF]

Front Med (Lausanne)
Xu K, Li M, Jiang P.
europepmc   +1 more source

26 Opportunistic infections in inflammatory bowel disease: are we adhering to the ecco guidelines?

, 2017
Oliver Reed, N. J. Bradley, Rebecca Hall, G. Subraya Bhat   +3 more
openalex   +1 more source