Results 291 to 300 of about 1,254,762 (395)

Thrombosis as a Complication of Inflammatory Bowel Disease in Children

, 1985
Khazal Paradis, Mark L. Bernstein, Joel W. Adelson   +2 more
openalex   +1 more source

Kinsenoside‐Loaded Microneedle Accelerates Diabetic Wound Healing by Reprogramming Macrophage Metabolism via Inhibiting IRE1α/XBP1 Signaling Axis

Advanced Science, EarlyView.
Gut metabolite trimethylamine N‐oxide accumulates in the diabetic wound area to amplify macrophage inflammation via enhancing glycolysis activities. Kinsenoside induces macrophage repolarization from M1 to M2 phenotype through inhibiting IRE1α/XBP1 pathway, followed by HIF‐1α‐glycolysis axis repression and mitophagy‐oxidative phosphorylation axis ...
Li Lu, Jiewen Liao, Chao Xu, Yuan Xiong, Juan Zhou, Guangji Wang, Ze Lin, Kangkang Zha, Chuanlu Lin, Ruiyin Zeng, Guandong Dai, Qian Feng, Bobin Mi, Guohui Liu   +13 more
wiley   +1 more source

Cardiotonic Steroids as a Potential Novel Approach for Immunomodulation in Inflammatory Bowel Disease. [PDF]

J Clin Med
Cavalcante-Silva LHA, Sales-Neto JM, Soares MM, Ferreira DA, Medeiros ABA, Rodrigues-Mascarenhas S.   +5 more
europepmc   +1 more source

Gasdermin D‐Mediated Pyroptosis Exerts Two Opposite Effects of Resisting Enzymatic Digestion and Expanding Inflammatory Response in Acute Pancreatitis

Advanced Science, EarlyView.
Gasdermin D (GSDMD) does not only reduce pancreatic enzyme synthesis but also induces pancreatic acinar cells to express mucin 1 (MUC1), which forms a barrier to prevent digestive enzyme‐mediated digestion. However, GSDMD can promote the secretion of inflammatory cytokines by macrophages and aggravate pancreatic histological injury by expanding ...
Chaoxu Liu, Ning Liang, Chen Wu, Zhaoyan Qiu, Qian Huang, Xiaolong Wei, Shurong Zhang, Shuanghong Lei, Tao Yang, Gang Wang, Qian Wang   +10 more
wiley   +1 more source

Obesity and Clinical Characteristics of Inflammatory Bowel Disease. [PDF]

Obes Facts
Mancone R, Biancone L, Schiavone SC, Fiorillo M, Menna C, Migliozzi S, Neri B.   +6 more
europepmc   +1 more source

Hepatotoxic Effect of Bile Acids in Inflammatory Bowel Disease

, 1980
M. J. Dew, G. P. van Berge Henegouwen, A. W. M. Huybregts, R N Allan   +3 more
openalex   +1 more source

Gut Microbiota Modulates Obesity‐Associated Skeletal Deterioration Through Macrophage Aging and Grancalcin Secretion

Advanced Science, EarlyView.
Obese gut‐microbiota derived lipopolysaccharides (LPS) induce bone marrow macrophage senescence and GCA secretion via activating TLR4/NF‐κB/MAPKs pathway. Clinically, obese patients are associated with higher serum GCA levels. Mice with depletion of GCA gene show resistance to skeletal deterioration caused by obesity and LPS‐induced chronic ...
Min Huang, Mei Huang, Ling Liu, Fang Yang, Chen He, Yu‐Chen Sun, Yu‐Rui Jiao, Xiang Tang, Jing Hou, Kai‐Xuan Chen, Wen‐Zhen He, Jie Wei, Hui‐Ling Chen, Xia Li, Chao Zeng, Guang‐Hua Lei, Chang‐Jun Li   +16 more
wiley   +1 more source

Impact of Microbiota Diversity on Inflammatory Bowel Disease. [PDF]

Microorganisms
Alzahrani AJ, Al-Hebshi BM, Yahia ZA, Al-Judaibi EA, Alsaadi KH, Al-Judaibi AA.   +5 more
europepmc   +1 more source

Peripheral Blood Mononuclear Cells From Patients With Inflammatory Bowel Disease Exhibit Normal Function in the Allogeneic and Autologous Mixed Leukocyte Reaction and Cell-Mediated Lympholysis

, 1984
Richard P. MacDermott, M. Janice Bragdon, R. Donogene Thurmond   +2 more
openalex   +1 more source