Results 321 to 330 of about 1,342,022 (369)

Chronic PET‐Microplastic Exposure: Disruption of Gut–Liver Homeostasis and Risk of Hepatic Steatosis

Advanced Science, EarlyView.
Chronic exposure to environmentally relevant PET microplastics disrupts gut–liver homeostasis, leading to hepatic steatosis, early fibrosis, and altered gut microbiota. These effects signal metabolic imbalance and gut–liver axis impairment, emphasizing chronic microplastic ingestion as an emerging environmental health risk linked to non‐communicable ...
Surye Park, Min‐Ji Kim, Jae‐Ho Shin, Eunsoo Kim, Myeongjoo Son, Seungjun Lee   +5 more
wiley   +1 more source

Targeting pyroptosis in inflammatory bowel disease: A potentially effective therapeutic approach. [PDF]

World J Gastroenterol
Dong WW, Liu T, He LX, He WT.
europepmc   +1 more source

Programmable Hydrogels: Frontiers in Dynamic Closed‐Loop Systems, Biomimetic Synergy, and Clinical Translation

Advanced Science, EarlyView.
This review summarizes the design principles and key features of programmable hydrogels that respond to multiple stimuli. It then delves into the cutting‐edge mechanisms of self‐executing systems, highlighting their role as the cornerstone of next‐generation programmable hydrogels (NGPHs).
Guangli Xiang, Bohan Yin, Behzad Shiroud Heidari, George Youssef, Monika Gosecka, Mateusz Gosecki, Fernando G. Torres, Siu Hong Dexter Wong, Jagan Mohan Dodda   +8 more
wiley   +1 more source

Editorial: Advancing inflammatory bowel disease treatment through nutritional interventions. [PDF]

Front Nutr
Bueno-Hernández N, Vivanco Karlsson N, Mendoza-Martínez VM, Serralde-Zúñiga AE.   +3 more
europepmc   +1 more source

Inflammatory Bowel Diseases and Nephropathies: Exploring the Gut–Kidney Axis

Roberto de Sire, Alessia La Mantia, Livio Bonacci, Anna Testa, Alessia Dalila Guarino, Antonio Rispo, Olga Maria Nardone, Fabiana Castiglione   +7 more
openalex   +1 more source

Tubule‐Derived IFN‐α Promotes GSDMD‐Mediated Macrophage Pyroptosis to Drive Renal Inflammation and Fibrosis Through JAK2/STAT2 Activation

Advanced Science, EarlyView.
Mao and colleagues uncover a STAT2/IRF9‐dependent signaling axis through which tubular epithelial cell (TEC)‐derived IFN‐α induces gasdermin D (GSDMD)‐mediated pyroptosis in macrophages. This TEC‐macrophage feedback loop amplifies renal inflammation and fibrosis, providing mechanistic insight into the progression of chronic kidney disease and revealing
Yiping Xu, Yating Wang, Siming Jiang, Yi Li, Guanglan Li, Yuchu Liu, Siyuan Li, Yiming Zhou, Qinghua Liu, Yi Zhou, Wei Chen, Hongyu Li, Haiping Mao   +12 more
wiley   +1 more source

Emerging Therapies in Inflammatory Bowel Disease: A Comprehensive Review. [PDF]

J Clin Med
Appiah JK, Hayat U, Garg N, Asante R, Donneyong E, Haider MU, Patel P, Khan Z, Siddiqui AA.   +8 more
europepmc   +1 more source

Structure‐Tailoring Cerium Nanozymes with Self‐Cascade ROS Scavenging Catalysis Modulate the Microbiota‐Gut‐Joint Axis for Rheumatoid Arthritis Therapy

Advanced Science, EarlyView.
A valence‐engineered CeOX nanozyme, with its Ce3+/Ce4+ ratio precisely controlled within the range of 0.27 to 0.93 through Au deposition, performs a self‐cascade oxidase‐superoxide dismutase‐peroxidase reaction, enabling continuous reactive oxygen species scavenging while minimizing oxygen generation.
Ge Wang, Xueqing Zhang, Boyuan Zhu, Suyue Ding, Dong Yan, Jing Ma, Yafang Xiao, Yafu Wang, Tianjun Ni, Hua Zhang, Weisheng Guo   +10 more
wiley   +1 more source

Gut virome and its emerging role in inflammatory bowel disease. [PDF]

World J Methodol
Khokhar RK, Nashwan AJ.
europepmc   +1 more source