Results 261 to 270 of about 987,528 (333)

Anti‐Inflammatory Mechanisms of Selenium Nanosheets in Ulcerative Colitis: Protein Corona, GP130 Interaction, and Transcriptomic Profile

Advanced Science, EarlyView.
SeNSs provide a biocompatible, anti‐inflammatory UC therapy. SeNSs form protein coronas enriched with AKT/PI3K/NF‐κB pathway proteins, suppress GP130 via hydrophobic interactions, and inhibit pro‐inflammatory cytokines. In DSS‐induced UC mice, SeNSs reduce inflammation, tissue damage, and disease activity by modulating cytokine, chemokine, and ...
Dingyi Shen, Li Gong, Wei Yang, Jiaqi Luo, Zhen Jin, Youzhi Tang   +5 more
wiley   +1 more source

Causal effects of brain subregion gene expression on inflammatory bowel diseases revealed by Mendelian randomization and single cell analysis. [PDF]

Sci Rep
Li Y, Wang Y, Chen S, Liu L.
europepmc   +1 more source

Peripheral Blood Mononuclear Cells From Patients With Inflammatory Bowel Disease Exhibit Normal Function in the Allogeneic and Autologous Mixed Leukocyte Reaction and Cell-Mediated Lympholysis

, 1984
Richard P. MacDermott, M. Janice Bragdon, R. Donogene Thurmond   +2 more
openalex   +1 more source

The Molecular Basis of Amino Acids Sensing

Advanced Science, EarlyView.
Amino acids are essential as protein building blocks and signaling molecules, enabling metabolic regulation. Cells sense amino acid levels to control protein synthesis, maintain homeostasis, and adapt to nutritional changes. This review explores recent advances in amino acid sensing mechanisms across organisms, highlighting their roles in cellular ...
Cong Jiang, Xiao Tan, Jiali Jin, Ping Wang   +3 more
wiley   +1 more source

Telocytes in inflammatory bowel diseases: contributions to pathology and therapeutic potentials. [PDF]

Front Cell Dev Biol
Panganiban RP, McAninch C, Chulkina M, Pinchuk IV.   +3 more
europepmc   +1 more source

Kinsenoside‐Loaded Microneedle Accelerates Diabetic Wound Healing by Reprogramming Macrophage Metabolism via Inhibiting IRE1α/XBP1 Signaling Axis

Advanced Science, EarlyView.
Gut metabolite trimethylamine N‐oxide accumulates in the diabetic wound area to amplify macrophage inflammation via enhancing glycolysis activities. Kinsenoside induces macrophage repolarization from M1 to M2 phenotype through inhibiting IRE1α/XBP1 pathway, followed by HIF‐1α‐glycolysis axis repression and mitophagy‐oxidative phosphorylation axis ...
Li Lu, Jiewen Liao, Chao Xu, Yuan Xiong, Juan Zhou, Guangji Wang, Ze Lin, Kangkang Zha, Chuanlu Lin, Ruiyin Zeng, Guandong Dai, Qian Feng, Bobin Mi, Guohui Liu   +13 more
wiley   +1 more source

Probiotic Microorganisms in Inflammatory Bowel Diseases: Live Biotherapeutics as Food. [PDF]

Foods
Santos EN, Magalhães-Guedes KT, Borges FEM, Ferreira DD, da Silva DF, Conceição PCG, Lima AKC, Cardoso LG, Umsza-Guez MA, Ramos CL.   +9 more
europepmc   +1 more source

A Possible mechanism of action of sulfasalazine and 5-aminosalicylic acid in inflammatory bowel diseases: Interaction with oxygen free radicals

, 1985
Piero Del Soldato, Massimo Campieri, C. Brignola, Gabriele Bazzocchi, Paolo Gionchetti, Giorgio Assuero Lanfranchi, Michiko Tamba   +6 more
openalex   +1 more source

Gasdermin D‐Mediated Pyroptosis Exerts Two Opposite Effects of Resisting Enzymatic Digestion and Expanding Inflammatory Response in Acute Pancreatitis

Advanced Science, EarlyView.
Gasdermin D (GSDMD) does not only reduce pancreatic enzyme synthesis but also induces pancreatic acinar cells to express mucin 1 (MUC1), which forms a barrier to prevent digestive enzyme‐mediated digestion. However, GSDMD can promote the secretion of inflammatory cytokines by macrophages and aggravate pancreatic histological injury by expanding ...
Chaoxu Liu, Ning Liang, Chen Wu, Zhaoyan Qiu, Qian Huang, Xiaolong Wei, Shurong Zhang, Shuanghong Lei, Tao Yang, Gang Wang, Qian Wang   +10 more
wiley   +1 more source

Prevalence, Clinical Features, and Extraintestinal Manifestations in Patients with Familial Inflammatory Bowel Diseases. [PDF]

Dig Dis Sci
Liava C, Chourmouzi D, Sinakos E, Dimitroulas T, Navrozidou C, Akriviadis E.   +5 more
europepmc   +1 more source